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Moving toward personalizing MELD exceptions in liver transplantation for hepatocellular carcinoma

from American Journal of Transplantation

Hepatocellular carcinoma (HCC) has become a leading indication for liver transplantation (LT) in the U.S. over the past two decades, accounting for nearly 25% of all LTs conducted yearly. Access to HCC‐related LT has been accomplished primarily through granting Model for End‐Stage Liver Disease (MELD) exception points, which aim to balance the risk of death and waitlist dropout with post‐LT HCC recurrence. Given the finite number of organs, this increase in HCC‐related LT has come at the expense of patients with end‐stage liver disease. more

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