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ASCLS eNewsBytes
March 23, 2010
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NCCN guideline on occult cancer show immunohistochemistry is "rapidly changing"
Medscape Medical News    Share   Share on FacebookTwitterShare on LinkedinE-mail article
The addition of new markers that add "a lot more breadth and depth" to immunohistochemical microscopy for the attempted diagnosis of cancer of an unknown primary origin is the major change in the National Comprehensive Cancer Network (NCCN)'s guideline for these occult tumors. Immunohistochemical microscopy is "rapidly changing" because of the introduction of new markers, said Charles Handorf, MD, PhD, from the University of Tennessee Cancer Institute in Chattanooga. More

Equitech


House democrats approve health care reform bill
HealthDay News via U.S.News & World Report    Share    Share on FacebookTwitterShare on LinkedinE-mail article
After a year of fierce partisan debate, the Democrat-controlled House of Representatives passed the landmark $940 billion health care reform bill, which would extend health insurance coverage to 32 million uninsured Americans, prevent insurance companies from denying coverage to people with preexisting medical conditions and cut the federal deficit by an estimated $138 billion over the next decade. More

FDA approves carglumic acid therapy for rare genetic disorder
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. Food and Drug Administration has approved carglumic acid dispersible tablets (Carbaglu, Orphan Europe, a Recordati company) for treatment of a rare genetic disoder N-acetylglutamate synthase deficiency, which causes hyperammonemia. This deficiency is a rare autosomal genetic disorder characterized by extremely high ammonia plasma levels that can cause permanent and irreversible central nervous system damage. Symptoms start shortly after birth, leading to cerebral edema, coma, and death if immediate detection and treatment do not take place. More

'Super mosquitoes' could fight malaria with a bite
CNN    Share    Share on FacebookTwitterShare on LinkedinE-mail article
They are normally transmitters of the disease, but mosquitoes could one day be used to tackle malaria after scientists developed a genetically engineered version of the species that can deliver a vaccine. Researchers altered the salivary glands of the Anopheles stephensi mosquito, dubbed a "flying vaccinator," so that it carried the Leishmania vaccine within its saliva. More
Beckman Coulter


Nanotech robots deliver gene therapy through blood
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
U.S. researchers have developed tiny nanoparticle robots that can travel through a patient's blood and into tumors where they deliver a therapy that turns off an important cancer gene. More

How bananas could help prevent the spread of HIV
TIME magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In laboratory tests, a chemical derived from bananas proved as effective against HIV as two currently used pharmaceuticals, according to new research published in the March 19 issue of the Journal of Biological Chemistry. Dr. David Markovitz and colleagues at the University of Michigan found that a lectin, or protein, in bananas may be able to interrupt the chain reaction that leads to HIV transmission. The chemical, called BanLec, limits the spread of HIV by binding to a protein in the virus and blocking its ability to spread infection to the body. More

Stem cell creation enhanced with geometry
UPI    Share    Share on FacebookTwitterShare on LinkedinE-mail article
University of Chicago scientists say they have used geometrically patterned surfaces in a new approach to influence the development of stem cells. Researchers said their procedure is a departure from that of many stem-cell biologists, who focus instead on uncovering the role of proteins in controlling the fate of stem cells. More

StatSpin® CytoFuge 12
The NEW StatSpin® CytoFuge 12 is a compact, low cost cytocentrifuge that concentrates 12 samples from 50 µL up to 800 µL onto microscope slides for a variety of cell preparations. Inside is a removable sealed autoclavable rotor that can be loaded in a hood to eliminate exposure to biohazards. The program key pad is easy to use; up to 24 programs can be stored. The unit operates from 200-2,000 rpm. More info



Infectious disease physicians call for 10 new antibiotics by 2020
Infection Control Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
As the deaths and suffering caused by antibiotic-resistant bacterial infections continue to rise around the world, the Infectious Diseases Society of America is urging a global commitment to develop 10 new antibiotics by 2020, known as the 10 x '20 initiative, to address this public health crisis and safeguard patients' health. The plea for U.S. and global action comes in a statement-published in the Clinical Infectious Diseases that outlines the dangers and recommends how to address what the World Health Organization has identified as one of the three greatest threats to human health. More

Scientists find key genes which control blood-clotting
BBC    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Edinburgh scientists in the U.K., have identified key genes which could help shed light on the causes of deep vein thrombosis and some types of stroke. The Edinburgh University team has discovered three genes which control how long it takes blood to clot. More

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