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Apr. 3, 2012
eNewsBytes
Apr. 3, 2012
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Finding multiple mutations in cancer:
science vs the media

Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nationally renowned oncologist Dr. Maurie Markman, national director for medical oncology at Cancer Treatment Centers of America, discusses a paper found in the New England Journal of Medicine, titled: "Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing." According to Markman, "The paper demonstrated ... that within an individual cancer — and even an individual mass in that cancer — one can see multiple patterns, mutations, and pathways that are arranged in an abnormal manner. Of course, we must be concerned about the impact of this heterogeneity on outcome." More




FDA approves additional blood test for viruses linked to leukemia, neurologic diseases
U.S. Food and Drug Administration    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Avioq HTLV-I/II Microelisa System, a test designed to detect antibodies to viruses in donors of human blood and blood components that are associated with several diseases, including some forms of leukemia and neurologic diseases, was approved by the U.S. Food and Drug Administration. Avioq HTLV-I/II Microelisa System, is the only test now available that can be used to both screen the blood supply for antibodies to Human T-Lymphotropic Virus Type I (HTLV-I) and Human T-Lymphotropic Virus Type II (HTLV-II), and help diagnose infection with these viruses. More

New breast cancer susceptibility gene
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Mutations in a gene called XRCC2 cause increased breast cancer risk, according to a study published in the American Journal of Human Genetics. The study looked at families that have a history of the disease but do not have mutations in the currently known breast cancer susceptibility genes. More

Tiny reader makes fast, cheap DNA sequencing feasible
Lab Manager Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available. The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes or addiction. More

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House passes budget plan shaking up Medicare, Medicaid
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the wake of the Supreme Court hearings on the Affordable Care Act that left its survival in doubt, the GOP-controlled House yesterday approved a budget that would repeal healthcare reform and partially privatize Medicare. The measure comfortably passed in a 228-191 vote, but it faces impossible odds in a Democrat-controlled Senate, and a veto-wielding White House already has given it a failing grade. More

HEDIS data provides evidence that physicians are more effective in using clinical pathology laboratory tests improve patient care
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For almost a decade now, clinical laboratories and pathology groups have been asked by many private payers to provide laboratory test data for a number of clinical services. In turn, these private health insurers annually submit this data to the Healthcare Effectiveness Data and Information Set (HEDIS) program managed by the National Committee for Quality Assurance. More

Legos helps build synthetic bones
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Engineering isn't all glamor. In the course of devising and producing the stuff that improves all our lives, the lab often becomes home to laborious procedures that can start to sap the strength of even the hardiest engineers. More




Lab and pathologist collaboration
Advance for Administrators of the Laboratory    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Financial incentives alone won't create collaboration. Laboratory management and pathologists must build trust and the ability to collaborate before entering into new contractual arrangements. Good partners create good partnerships, not the other way around. More

Trends in salary, compensation, and benefits is nation's oldest for medical laboratory CEOs, executives and administrators
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For the fourth consecutive year, a reliable national survey of compensation trends for clinical laboratory executives, administrators, directors, pathologists and managers was conducted. The first findings of this survey will be presented on May 1 at the Executive War College on Laboratory and Pathology Management in New Orleans. More

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Hepatitis E infected more than 20 million worldwide annually
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An estimated 20.1 million people in 9 regions of Africa and Asia were infected with hepatitis E virus (HEV) in 2005, according to a study published in Hepatology. HEV is an enterically transmitted RNA virus that can cause outbreaks or sporadic disease, and large outbreaks are typical in developing countries with contaminated water. More

11 telemedicine tools transforming healthcare
InformationWeek    Share    Share on FacebookTwitterShare on LinkedinE-mail article
What's fueling the healthcare industry's interest in telemedicine? Better mobile technologies and more mature electronic health records (EHRs) and clinical decision support systems lead the list. Also, as the baby boomer generation ages, medical expert shortages arise in many specialties. More




US requires new dual-use biological research reviews
ScienceInsider    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. government released a new policy that will require federal agencies to systematically review the potential risks associated with federally funded studies involving 15 "high consequence" pathogens and toxins, including the H5N1 avian influenza virus. The reviews are designed to reduce the risks associated with "dual use research of concern" that could be used for good or evil. More

A blood test without bleeding
medGadget via The Atlantic    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In this video news brief, from TED2012, TED fellow Myshkin Ingawale gave a talk on how he helped to develop a prick-free blood hemoglobin measurement device. His technology, conceived after 32 tries, seems to focus specifically on the developing world where cost and access are serious problems. More

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In cancer science, many 'discoveries' don't hold up
Reuters via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A former researcher at Amgen Inc says many basic studies on cancer -- a high proportion of them from university labs -- are unreliable, with grim consequences for producing new medicines in the future. More

Key enzyme involved in protecting nerves from degeneration identified
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new animal model of nerve injury has brought to light a critical role of an enzyme called Nmnat in nerve fiber maintenance and neuroprotection. Understanding biological pathways involved in maintaining healthy nerves and clearing away damaged ones may offer scientists targets for drugs to mitigate neurodegenerative diseases such as Huntington's and Parkinson's, as well as aid in situations of acute nerve damage, such as spinal cord injury. More




Robots will be able to feel sooner than you think
SmartPlanet    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a recent paper published in Advanced Functional Materials, a team of researchers from the University of Pittsburgh and the Massachusetts Institute of Technology have demonstrated the use of a nonoscillating gel that can be resuscitated in a similar manner to medical cardiopulmonary resuscitation. In the same way that human skin provides signals to the brain when there is an external pressure, pain or environmental change, the Belousov-Zhabotinsky gel (first developed in the 1990s) could become the "holy grail" of robotics — by functioning as a sensory, artificial skin. More

Collecting cancer data
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Broad Institute and Sanger Institute announced details from their separate cancer cell line databases, the largest such repositories of genomic and drug profiling data to date. With preliminary results published in two Nature papers, the databases should help researchers identify which drugs to use against which cancers to streamline drug development efforts. More
CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
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Trust in Cleveland Clinic Laboratories
Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit clevelandcliniclabs.com.
Structured data capture for non-interfaced labs

Learn how Aurora Advanced Healthcare is using LabDE to improve lab data entry workflow and increase data interoperability. LabDE automatically recognizes and highlights blocks of crucial text, including test name, code, value units, reference range and flags, and incorporates these fields as structured data into the EHR/LIS. Watch the video.
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