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ASCLS eNewsBytes
May 25, 2010
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New mutant genes linked to rheumatoid arthritis
Reuters via Medscape Today    Share   Share on FacebookTwitterShare on LinkedinE-mail article
A large study of European populations has uncovered seven new clusters of defective genes that may be responsible for rheumatoid arthritis. The paper was published online in Nature Genetics, together with findings of a separate study in Japan, which identified one of the seven genetic clusters as possibly causing the chronic inflammatory disease among Japanese. "The findings leverage us to better understand the basic biology of rheumatoid arthritis, with the goals of developing new targets for therapy and new biomarkers for diagnosis and prognosis," wrote Dr. Eli Ayumi Stahl at the Brigham and Women's Hospital in Boston in the United States, who led the study on European populations. More

Equitech


Markers of microbial translocation and immune function in chronic HIV infection
Medscape Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A decline in CD4 count is central to the immune deficiency associated with HIV infection, but the cause of CD4 cell depletion is not completely understood. HIV replicates within CD4 cells and can destroy them, but this does not entirely explain the CD4 cell depletion. Furthermore, chronic immune activation seems to correlate with disease progression and CD4 cell loss. More

University of Arkansas research will accelerate development of clinical laboratory blood test for breast cancer
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A simple clinical pathology laboratory blood test for early detection of breast cancer may be just around the corner. At the University of Arkansas, researchers are building a library of synthetic antibodies called affitoids that can be used to detect breast cancer in its earliest stage. Researchers believe they are closing in on the creation of an assay that can rapidly validate proteins secreted by microscopic breast cancer cells. More

Diagnosis and Management of H pylori Infection
MedscapeCME Clinical    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
A clinical review in the New England Journal of Medicine provides information on how to detect, diagnose, treat, and manage Helicobacter pylori infection. "Infection with H. pylori is a cofactor in the development of three important upper gastrointestinal diseases: duodenal or gastric ulcers, gastric cancer, and gastric mucosa-associated lymphoid-tissue lymphoma ," writes Kenneth E. L. McColl, MD, from the Division of Cardiovascular and Medical Sciences, University of Glasgow in theUnited Kingdom. "The risk of these disease outcomes in infected patients varies widely among populations. The great majority of patients with H. pylori infection will not have any clinically significant complications." More
Beckman Coulter


Salmonella outbreak prompts alfalfa sprout recall
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Caldwell Fresh Foods voluntarily recalled alfalfa sprouts manufactured under the Caldwell Fresh Foods, Nature's Choice, and California Exotics brands. Salmonella can cause serious and possibly fatal infections in young children, the elderly, and others with weakened immune systems. Healthy persons infected with salmonella can experience fever, diarrhea, nausea and abdominal pain. More

Simple electronic gadget could speed up HIV/AIDS diagnostics
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
A relatively simple electronic gadget could speed up HIV/AIDS diagnostics and improve accuracy particularly in parts of the world with very limited access to health care workers. The device is described in the International Journal of Biomedical Engineering and Technology. More

CDC: 1 in 8 pools may pose infection risk
ABC News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Before plunging into your local public pool, you might want to stop and think about what you might be plunging into. The pool might not be as sanitary as it should be, according to a report by the Centers for Disease Control and Prevention. Researchers found that 1 out of 8 pools had to be closed immediately for serious code violations. More

StatSpin® CytoFuge 12
The NEW StatSpin® CytoFuge 12 is a compact, low cost cytocentrifuge that concentrates 12 samples from 50 µL up to 800 µL onto microscope slides for a variety of cell preparations. Inside is a removable sealed autoclavable rotor that can be loaded in a hood to eliminate exposure to biohazards. The program key pad is easy to use; up to 24 programs can be stored. The unit operates from 200-2,000 rpm. More info



Microalbuminuria may predict renal, cardiovascular disease in hypertensive patients
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail
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Microalbuminuria may predict renal and cardiovascular disease in patients with hypertension but without diabetes, according to the results of a study reported online April 29 in the Clinical Journal of the American Society of Nephrology. "Our findings emphasize the usefulness of a more widespread evaluation of microalbuminuria in an effort to guide the management of hypertension," said senior author Roberto Pontremoli, MD, PhD, from the University of Genoa in Genoa, Italy, in a news release. More

WHO says measles making 'rapid comeback'
The Associated Press via Google News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Measles is making a rapid comeback in African, Asian and even some European countries despite being easily avoided through vaccination, the World Health Organizations said as countries pledged to sharply cut infections and deaths worldwide by 2015. Since 2008, funding cuts for vaccination campaigns have allowed measles to spread again where previously it was close to being eradicated, the global body said. More

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