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ASCLS eNewsBytes
June. 1, 2010
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Scientists: Breast cancer vaccine possible
HealthDay News    Share   Share on FacebookTwitterShare on LinkedinE-mail article
A study in mice suggests that a preventive breast cancer vaccine might be possible in humans, scientists say. Women may begin taking part in the next stage of research as soon as next year, they added. "We believe that this vaccine will someday be used to prevent breast cancer in adult women in the same way that vaccines have prevented many childhood diseases," principal investigator Vincent Tuohy, an immunologist in Cleveland Clinic's Lerner Research Institute, said in a news release. "If it works in humans the way it works in mice, this will be monumental. We could eliminate breast cancer." More

Equitech


New way bacterium spreads in hospital
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Health care workers and patients have yet another source of hospital-acquired infection to worry about, British researchers are reporting. Clostridium difficile, a germ that causes deadly intestinal infections in hospital patients, has long been thought to be spread only by contact with contaminated surfaces. But a new study finds that it can also travel through the air. The researchers emphasized that there is no evidence that C. difficile can be contracted by inhaling the germs. Rather, they float on the air, landing in places where more people can touch them. More

Gene variants increase susceptibility to malaria, tuberculosis and bacteremia
MedScape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study has shown that CISH variants are associated with increased susceptibility to severe malaria, tuberculosis and bacteremia. CISH (cytokine-inducible SRC homology 2 domain protein) mediates cytokine signaling, and specifically the proinflammatory response resulting from the cytokine interleukin 2. An excessive inflammatory response can harm the host, and normal CISH blocks cytokine receptors and inhibits cytokine signaling; the CISH variants reduce this modulation. More

Novel therapeutic approach shows promise against multiple bacterial pathogens
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team of scientists from government, academia and private industry has developed a novel treatment that protects mice from infection with the bacterium that causes tularemia, a highly infectious disease of rodents, sometimes transmitted to people, and also known as rabbit fever. More
Beckman Coulter


Array-based cytogenetic testing
Clinical Laboratory News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The gain or loss of genetic material causes many human genetic disorders. Today, we also know that most cancers acquire DNA copy number changes during the life of the patient or the tumor. These genomic gains and losses may result in congenital anomalies, dysmorphic features, developmental disabilities, or other neurological abnormalities, as well as tumor initiation or progression. Until recently, traditional chromosome analysis was the primary tool for the cytogenetic assessment of patients with these clinical concerns. More

Modified measles virus shows potential for treating childhood brain tumors
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The use of modified measles virus may represent a new treatment for a childhood brain tumor known as medulloblastoma, according to a new study appearing in Neuro-Oncology. Medulloblastoma is the most common malignant central nervous system tumor of childhood, accounting for about 20 percent of pediatric brain tumors. These tumors are located in the cerebellum, the area of the brain that controls balance and other complex motor functions. More

Researchers try new approaches to preventing HIV
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Tablets, insertable rings and dissolving films can effectively deliver drugs to help protect women and perhaps men from infection with the AIDS virus, researchers reported. They also found evidence that using such an approach -- called a microbicide -- may help overcome some of the risks of drug resistance that can come with taking pills to prevent infection. More

StatSpin® CytoFuge 12
The NEW StatSpin® CytoFuge 12 is a compact, low cost cytocentrifuge that concentrates 12 samples from 50 µL up to 800 µL onto microscope slides for a variety of cell preparations. Inside is a removable sealed autoclavable rotor that can be loaded in a hood to eliminate exposure to biohazards. The program key pad is easy to use; up to 24 programs can be stored. The unit operates from 200-2,000 rpm. More info



Stanford study shows how pathologists may eventually use the whole human genome for diagnostic purposes
Dark Daily via Google News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For pathologists, the day draws ever closer when they will use a patient's whole genome sequence for diagnostic purposes. That's the implication from research being done at the University of Stanford Medical School where scientists recently made a leap forward in advancing practical application of the human genome to patient care. More

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