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Home   About   Scholarships   Meetings   Publications   Resources   Jun. 5, 2012

 


PD-1 agent 'breaks ceiling' in cancer immunotherapy
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new immune-targeted approach to cancer treatment is being heralded as the next big thing in oncology after two investigational agents produced unprecedented durable tumor response rates in three cancers in early trials. The approach uses monoclonal antibodies to neutralize the programmed death 1 protein and its partner molecule, elements of tumors that enable them to evade their nemesis — the immune system. More

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Needle-free hematology and clinical laboratory blood tests may
be coming to point-of-care settings

Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Israeli researchers developed a microscope with cellular resolution that uses a rainbow of light to image blood cells in vivo as they flow through a microvessel. Experts familiar with the research project say the technology has the potential to find a ready role in clinical diagnostics. More

Speeding up drug discovery with rapid 3-D mapping of proteins
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published in Nature Methods. The technique, developed by scientists at the Salk Institute for Biological Studies, provides a shortcut for determining the structure of human integral membrane proteins, molecules found on the surface of cells that serve as the targets for about half of all current drugs. More



Detecting cancers — from tiny bits of tumor DNA in blood
Los Angeles Times (blog)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When cancer blooms in the body, tiny bits of tumor DNA can be found in the blood. Cancer specialists would love it if these DNA fragments could one day be used in noninvasive diagnostic tests – "liquid biopsies" – that are relatively inexpensive and sensitive. More

Pharma companies, publishers agree on publishing guidelines
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pharmaceutical industry and publishing representatives have collaborated to develop 10 recommendations for closing the credibility gap in reporting industry-sponsored clinical research. The report was published in the May issue of the Mayo Clinic Proceedings. Despite earlier industry efforts to improve publishing standards, "a credibility gap remains: some observers, including some journal editors and academic reviewers, maintain a persistent negative view of industry-sponsored studies," they note. More


CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
Triturus - True Open Flexibility
As a leader in fully automated immunoassay testing systems, Grifols USA Diagnostic Division’s premier product, the TRITURUS® ELISA System is an open, fully automated, multi-test and multi-batch immunoassay system. Grifols USA is a major distributor of quality IVD ELISA tests for Infectious Disease, Autoimmune Diseases and many other disease states. Grifols’ Diagnostic products take the complexity out of clinical diagnostic testing.

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Trust in Cleveland Clinic Laboratories
Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit clevelandcliniclabs.com.


Preventing misdiagnosis of MS
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Misdiagnosis of multiple sclerosis is becoming an increasingly recognized problem in the field, one expert says. Misdiagnosis is, "under-recognized, under-appreciated and under-studied," said Brian G. Weinshenker, M.D., from the Department of Neurology at Mayo Clinic College of Medicine in Rochester, Minn. More

New class of cancer drugs may be less toxic
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new class of cancer drugs may be more effective and less toxic than many existing treatments. By harnessing antibodies to deliver toxic payloads to cancer cells, while largely sparing healthy cells, the drugs are a step toward the "magic bullets" against cancer first envisioned by Paul Ehrlich, a German Nobel laureate, about 100 years ago. More



$900 point-of-care DNA nanopore sequencer may hit market
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Is the profession of pathology and clinical laboratory medicine ready to deal with point-of-care DNA sequencing technologies? A company in the United Kingdom says that, as early as next year, it can bring a portable high-throughput unit to market that will sell for around $900. The miniaturized sensing instrument, called MinION, is about the size of a USB memory stick and works with a normal laptop computer. More

Study suggests expanding the genetic alphabet may be easier
than previously thought

PhysOrg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study led by scientists at The Scripps Research Institute suggests that the replication process for DNA—the genetic instructions for living organisms that is composed of four bases — is more open to unnatural letters than had previously been thought. An expanded "DNA alphabet" could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from precise molecular probes and nanomachines to useful new life forms. More


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Screening new drugs with stem cells
Forbes (blog)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Mass-producing stem cells to screen drugs and study the progress of disease is not the sexier side of the field. But it's getting more attention now – and it's about time. The costs savings for drug development are substantial, as stem cells can be used to expose drugs with dangerous side effects before they reach the market. More

Patients with CAP leave hospital sooner with 3-step approach
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A simple three-step plan for treating patients with community-acquired pneumonia was safe and dramatically reduced hospital length of stay compared with usual care, while having no adverse effects on readmissions, mortality or patient satisfaction, according to new research findings. The three steps of the critical pathway involved the early mobilization of patients, followed by the use of objective criteria for switching to oral antibiotic therapy, and the use of predefined criteria for deciding on hospital discharge. More



Study: 'Bloodletting' may be beneficial
UPI    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Bloodletting as a medical treatment was abandoned in the 19th century, but German researchers said blood donation is beneficial to the donor. Professor Andreas Michalsen of the Charite-University Medical Centre in Berlin and colleagues at the University Duisburg-Essen said donating blood can provide medical benefits for obese people with metabolic syndrome – which includes insulin resistance, glucose intolerance, dyslipidemia and hypertension and leads to an increased risk of diabetes and cardiovascular disease. More

Aspirin: The new anti-cancer wonder drug?
Forbes    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It's the season when we worry about skin cancer. (Not to mention the anti-aging effects of the sun.) But what if the best preventative is right there in your medicine cabinet? New research reported in the journal Cancer found that people taking aspirin regularly were much more likely not to get squamous cell carcinoma or malignant melanoma, two of the most common – and deadliest – skin cancers. More

Expand your career as a Clinical Lab Scientist at UCSF Medical Center.

Opportunities available in San Francisco, CA in various areas - Chemistry, Hematology, Blood Bank, Immunology, Microbiology, Molecular Diagnostics, Bone Marrow Transplant, and Cytogenetics. Apply online or contact Cheryl Hardin at Cheryl.Hardin@ucsfmedctr.org for more information. EOE.


IST-3: Thrombolysis benefits even oldest stroke patients
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the largest trial of a thrombolytic drug to date, patients with acute ischemic stroke who received recombinant tissue plasminogen activator up to six hours after a stroke benefited in terms of being alive and capable of independent living at six months compared with a control group, regardless of age. Peter Sandercock, professor of medical neurology and honorary consultant neurologist in the Centre for Clinical Brain Sciences at the University of Edinburgh in Edinburgh, United Kingdom, reported the results of the third International Stroke Trial showing that mortality was higher in the first week for the patients receiving tPA but was no different from controls at six months. More

Why genetic tests don't help doctors predict your risk of disease
TIME    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Your DNA may hold valuable information about your health, but current genetic tests can't improve doctors' ability to predict your risk of major disease. More



Testosterone: An overview of CDC's standardization initiative
Clinical Laboratory News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The androgen steroid hormone, testosterone, plays a significant physiological role in both men and women, so being able to measure it accurately and reliably has important clinical implications. The Centers for Disease Control and Prevention, with broad input from various professional societies, is leading a Hormone Standardization Program with an initial focus on standardizing testosterone measurements. More

Fertility on hold for child cancer patients
Chicago Tribune    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A burgeoning field of research allows parents of young children diagnosed with cancer to consider their pre-pubescent child's ability to someday bear children — and to take steps to protect that ability. Because the aggressive methods necessary to treat certain types of cancers can cause infertility — and because pediatric patients' bodies aren't physically prepared to bear children — doctors are exploring fertility treatments that go beyond freezing eggs or freezing sperm. More
 


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