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ASCLS eNewsBytes
June. 15, 2010
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FDA clears new ovarian cancer test
Medscape Medical News    Share   Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. Food and Drug Administration has cleared a chemiluminescent microparticle immunoassay (Architect human epididymis protein 4 [HE4] assay; Abbott Diagnostics) for the quantitative determination of HE4 antigen, an ovarian cancer marker, in serum samples. HE4 measurements are intended for use in combination with other clinical data to monitor recurrence or progression of epithelial ovarian cancer. Epithelial ovarian cancer is the most common form of the ovarian cancer, which affects an estimated 1-in-71 women in the United States during their lifetimes. More

Equitech


Raised HDL may be bad news if inflammation present
Heartwire via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study has suggested that a raised HDL-cholesterol level, if present in conjunction with a raised C-reactive-protein level, may confer increased cardiovascular risk. And that in these patients, reduced cholesteryl-ester-transfer-protein activity is associated with even higher risk, giving a potential explanation to the negative findings of the torcetrapib (Pfizer) studies. More

Prescription for pain relief
Clinical Laboratory News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Over the past decade, recognition of the deleterious effects pain can have on quality of life and healing has increased substantially. Physicians now are more attuned to the need to alleviate patients’ pain and are writing an ever-growing number of prescriptions for pain medications. Although this focus on pain management is positive, it has presented some challenges for clinicians in terms of balancing the legitimate benefits of prescription pain therapy with the potential for misuse of the drugs. More

Bosutinib effective as second- and third-line therapy in CML
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
Patients with chronic myeloid leukemia (CML) who are resistant to first-line therapy might soon have another option. The investigational agent bosutinib (Pfizer) has demonstrated clinical efficacy in chronic-phase CML patients who failed previous therapy with imatinib (Gleevec), the current front-line treatment for this disease. More
Beckman Coulter


Pathologists take note: C. Craig Venter just created the first synthetic life form
DarkDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Now science can create synthetic life forms and J. Craig Venter, Ph.D., is the first to do it. The landmark feat, which involved building the genome of a bacterium from scratch and incorporating it into a cell, "paves the way for designer organisms that are built rather than evolved," noted the author. J. Craig Venter, Ph.D., best known to pathologists and clinical laboratory scientists for his role in sequencing the first human genome, achieved the feat at the J. Craig Venter Institute in Rockville, Md. Venter and his team synthesized the 1.08 million base pair chromosome of a modified Mycoplasma mycoides genome. More

New strain of bacteria discovered that could aid in oil spill, other environmental cleanup
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have discovered a new strain of bacteria that can produce non-toxic, comparatively inexpensive "rhamnolipids," and effectively help degrade polycyclic aromatic hydrocarbons, or PAHs — environmental pollutants that are one of the most harmful aspects of oil spills. More

StatSpin® CytoFuge 12
The NEW StatSpin® CytoFuge 12 is a compact, low cost cytocentrifuge that concentrates 12 samples from 50 µL up to 800 µL onto microscope slides for a variety of cell preparations. Inside is a removable sealed autoclavable rotor that can be loaded in a hood to eliminate exposure to biohazards. The program key pad is easy to use; up to 24 programs can be stored. The unit operates from 200-2,000 rpm. More info



Researchers hope human blood stem cells can cure HIV
WNDU-TV    Share    Share on FacebookTwitterShare on LinkedinE-mail article
VideoBrief
Despite 30 years of research, there is still no cure for the 1 million people in the U.S. living with HIV and AIDS. 56,000 more will find out they're HIV positive this year, but now scientists are looking inside a patient's own body for the solution. This month, thousands of people will take the HIV test, and June 27 is National HIV Testing Day. Despite 30 years of research, there is still no cure for the 1 million people in the U.S. living with HIV and AIDS. 56,000 more will find out they're HIV positive this year, but now scientists are looking inside a patient's own body for the solution.
More

A decade later, gene map yields few new cures
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Ten years after President Bill Clinton announced that the first draft of the human genome was complete, medicine has yet to see any large part of the promised benefits. For biologists, the genome has yielded one insightful surprise after another. But the primary goal of the $3 billion Human Genome Project — to ferret out the genetic roots of common diseases like cancer and Alzheimer’s and then generate treatments — remains largely elusive. Indeed, after 10 years of effort, geneticists are almost back to square one in knowing where to look for the roots of common disease. More

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