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Smartphone holograms can diagnose cervical cancer
New Scientist
Diagnosing disease is costly and time-consuming, especially in countries with limited resources. Ralph Weissleder of Massachusetts General Hospital, Boston, reckons digital holography – the construction of 3-D images of cells using a smartphone-compatible device – could help. To turn holography into a diagnostic tool, Weissleder's team first had to make different molecules, such as those collected during a smear or pap test, diffract light differently. They did this by adding microbeads, which bind to specific molecules – such as cancer markers or HPV DNA – and change their diffraction pattern.
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ASCT
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INDUSTRY NEWS


Study backs co-testing for cervical cancer
MedPage Today
Cervical cancer screening with a test for human papillomavirus (HPV) resulted in a 50 percent higher rate of false-negative results versus Pap testing and three times greater versus co-testing, a large retrospective study showed. Data encompassing more than 250,000 women showed a false-negative rate of 18.6 percent compared with 12.2 percent for Pap testing. With a false-negative rate of 5.5 percent, screening women with the HPV test and Pap test missed the fewest cancers.
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HPV-targeted T-cell therapy may induce cervical cancer regression
2 Minute Medicine
In a small, prospective trial of nine patients with metastatic cervical cancer, three patients demonstrated complete or partial response after a single infusion of T-cells reactive to HPV oncoproteins.
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Roche nabs EU approval for Avastin for cervical cancer
FiercePharma
Roche's Avastin has been on the market for more than a decade and boasts a long list of valuable approvals. But Roche is not sitting back the status quo, and continues to submit the drug for new uses. Now, the company racked up yet another OK for Avastin, scoring European approval for the drug in combination with chemotherapy to treat women with advanced cervical cancer months after the company got a similar decision from stateside regulators.
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HPV vaccination of adolescent boys may be cost-effective for preventing oropharyngeal cancer
Health Canal
A new study indicates that vaccinating 12-year-old boys against the humanpapilloma virus (HPV) may be a cost-effective strategy for preventing oropharyngeal squamous cell cancer, a cancer that starts at the back of the throat and mouth, and involves the tonsils and base of the tongue. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides important information about HPV vaccination, which has proven effective against HPV-related disease in both sexes but remains controversial, especially in males.
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MORE NEWS


Personalizing cancer treatment with genetic tests can be tricky
NPR
It's becoming routine for cancer doctors to order a detailed genetic test of a patient's tumor to help guide treatment, but often those results are ambiguous. Researchers writing in Science Translational Medicine say there's a way to make these expensive tests more useful. Here's the issue: These genomic tests scan hundreds or even thousands of genes looking for mutations that cause or promote cancer growth. In the process, they uncover many mutations that scientists simply don't know how to interpret — some may be harmless.
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MRI-based screening effective for pancreatic cancer detection
Healio
MRI screening effectively detected pancreatic lesions in patients at an elevated risk for pancreatic cancer, according to results of a prospective observational study. A specific pancreatic screening protocol has not been determined for individuals at higher risk due to genetics and/or family history, according to study background.
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ASCT Viewpoint
Colby Horton, Vice President of Publishing, 469.420.2601
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