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2014 revisions to 2013 ASHI Standards — public comment deadline — Sept. 5
The Quality Assurance and Standards Committee (QAS) has been working on updates to the 2013 ASHI Standards. There have been a variety of revisions recommended, but we wish to draw your particular attention to the following:
  • D.5.2.11 - "Laboratories Performing RFLP methods" has been deleted and in its place a new section on Next Generation Sequencing (NGS) has been added.
  • A number of new definitions pertaining to NGS have been added to the glossary.
  • D.5.3.8 - A new section on Virtual Crossmatching has been added.
  • All of the guidance sections now have reference numbers.
These proposed changes to the Standards have been submitted to the ASHI Board and the Accreditation Review Board (ARB) for review and comment. Now we seek your comments and suggestions.

Click here to view a redline version of the proposed 2014 Standards. Please carefully consider these proposed changes to the current standards and send your comments to Leslie Clark at ASHI Headquarters no later than Sept. 5.

QAS will respond to all comments received during the public comment period. Implementation of revisions to the standards will be on Jan. 1, 2015, following CMS review.
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ASHI University — exciting things are coming!
The ASHI Education Committee is excited to announce that ASHI University is about to launch a newly redesigned website for web-based learning. Along with the new website, there are newly designed modules. The “classic” ASHI modules are now being reformatted and provided with a new ASHI Procedure Manual chapter for each module. All new ASHI-U modules are being written with a procedure manual chapter as well.

The goal is to eventually update the entire procedure manual as a web-based resource. Look for the launch of the new ASHI-U website and new look coming soon, along with the first procedure manual chapters. In addition, ASHI will hold a “free day” later this year so that everyone can experience ASHI-U web-based learning for a day and see what a great value it is for ASHI members.

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Reminder: ASHI Quarterly quiz deadline is Sept. 1
Please note that the ASHI Quarterly quiz deadline and identification number were inadvertently left off the second quarter issue that was recently mailed out. The deadline to submit your quiz answers is Sept. 1, and the identification number is 38-2-2014. We apologize for any confusion.
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Annual meeting registration is open!
Click here to register now.

New this year! Join ASHI while registering for the meeting and save up to $135 on registration fees. Members who join now are paid through December 2015.

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Minor histocompatibility antigens as risk factor for poor prognosis in kidney transplantation
Transplantation Proceedings (subscription required)
Progress in transplantation has relied on similar human leukocyte antigen (HLA) matching between the donor and the patient, while the role of other immunologic factors like non-HLA markers including minor histocompatibility antigens (miHA) are currently in the forefront. miHA are polymorphic proteins that vary even in monozygotic twins. The best known is the H-Y antigen, but there are also other autosomal miHA and MICA. miHA have been extensively studied in transplantation of hematopoietic precursors, but not in solid organ transplantation.
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KIR diversity in Maori and Polynesians: Populations in which HLA-B is not a significant KIR ligand
Springer (subscription required)
HLA class I molecules and killer cell immunoglobulin-like receptors (KIR) form a diverse system of ligands and receptors that individualize human immune systems in ways that improve the survival of individuals and populations. Human settlement of Oceania by island-hopping East and Southeast Asian migrants started approximately 3,500 years ago. Subsequently, New Zealand was reached roughly 750 years ago by ancestral Māori. To examine how this history impacted KIR and HLA diversity and their functional interaction, scientists defined at high resolution the allelic and haplotype diversity of the 13 expressed KIR genes in 49 Māori and 34 Polynesians.
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ASHI Insights
Colby Horton, Vice President of Publishing, 469.420.2601
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