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A novel organ donor facility: A decade of experience with liver donors
American Journal of Transplantation (login required)
Transplant surgeons have historically traveled to donor hospitals, performing complex, time-sensitive procedures with unfamiliar personnel. This often involves air travel, significant delays and frequently occurs overnight. In 2001, the nation's first organ recovery center was established. The goal was to increase efficiency, reduce costs and reduce surgeon travel. Liver donors and recipients, donor costs, surgeon hours and travel time, from April 1, 2001 through Dec. 31, 2011 were analyzed.
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SOCIETY NEWS


RAPID software available free to ASTS members
ASTS
RAPID (Real-time Analysis and Process Improvement Dashboard) is a free and open-source software originally developed at Northwestern Medicine Comprehensive Transplant Center and distributed through ASTS at no charge to its members. RAPID provides outcomes and quality dashboards to individual transplant centers relevant to UNOS and SRTR reporting.
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ASTS Officer and Councilor ballot available
ASTS
The ballot for the 2014 Officer and Councilor Elections is now online at ASTS.org. In early April, all eligible voting members will receive a link to vote via a secure online system. Election results will be formally announced at the annual ASTS business meeting at WTC in July.
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Get the member rate at WTC
ASTS
Registration for the 2014 World Transplant Congress is now open, but you must be current on your ASTS dues to register at the member rate. 2014 ASTS membership dues invoices were sent out late last year and dues payments were due December 31, 2013.
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TOP NEWS


PRODUCT SHOWCASE
  SRTR Monitoring in Real-Time
XynManagement provides an integrated solution for transplant centers to identify SRTR risk, track outcomes and improve performance. XynManagement’s HIPPA-compliant, cloud-based software platform improves data capture, ensuring your data reflect the true risk of transplants performed. Using simple, effective graphics, the system predicts risk at the individual patient level and assesses program-wide risk on future SRTR reports.
 


Study: Uremic toxin development in living kidney donors
Transplantation (login required)
Emerging evidence suggests that uremic toxins, in particular indoxyl sulfate and p-cresyl sulfate, may be involved in the pathogenesis of cardiovascular disease. Despite a significant increase in IS and PCS in patients with established kidney damage, the effect of a nephrectomy in non–chronic kidney disease patients is not yet known.
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Dapsone-induced methemoglobinemia in renal transplant recipients: more prevalent than previously thought
Transplant Infectious Disease (login required)
After an outbreak of Pneumocystis pneumonia in our nephrology unit, dapsone was used as the second-line chemoprophylactic agent. Dapsone is the most common cause of drug-induced methemoglobinemia. Its prevalence is poorly described in the renal transplant population. Because dapsone is excreted by the kidneys, it has been hypothesized that the rate of MHb in these patients would be higher than previously reported. Authors aimed to describe the demographics, risk factors and presenting features of MHb in these renal transplant patients.
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Glutathione s-transferase iso-enzymes in perfusate from pumped kidneys are associated with delayed graft function
American Journal of Transplantation (login required)
Accurate and reliable assessment tools are needed in transplantation. The objective of this prospective, multi-center study was to determine the associations of the alpha and pi iso-enzymes of glutathione S-transferase, measured from perfusate solution at the start and end (base and post) of kidney allograft machine perfusion, with subsequent delayed graft function.
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Intermediate-term graft loss after renal transplantation is associated with both donor-specific antibody and acute rejection
Transplantation (login required)
Renal transplant recipients with de novo DSA experience higher rates of rejection and worse graft survival than dDSA-free recipients. This study presents a single-center review of dDSA monitoring in a large, multi-ethnic cohort of renal transplant recipients.
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Risk factors for nontuberculous mycobacterial infections in solid organ transplant recipients
Transplant Infectious Disease
The epidemiology of nontuberculous mycobacteria disease in solid organ transplant recipients is poorly defined. Authors conducted a case–control study to identify risk factors for disease, matching three control patients to each case patient by date of transplantation.
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Peritransplant absolute lymphocyte count as a predictive factor for advanced recurrence of hepatitis C after liver transplantation
Hepatology
Lymphocytes play an active role in natural immunity against hepatitis C virus (HCV). Authors hypothesized that a lower absolute lymphocyte count (ALC) may alter HCV outcome after liver transplantation (LT). The aim of this study was to investigate the impact of peritransplant ALC on HCV recurrence following LT. A total of 289 LT patients between 2005 and 2011 were evaluated. Peritransplant ALC (pre-LT, two-week, and one-month post-LT) and immunosuppression were analyzed along with recipient and donor factors in order to determine risk factors for HCV recurrence based on METAVIR fibrosis score.
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Additive effect of pretransplant obesity, diabetes and cardiovascular risk factors on outcomes after liver transplantation
Liver Transplantation (login required)
The effects of pretransplant obesity, diabetes mellitus coronary artery disease, and hypertension on outcomes after liver transplantation are controversial. Questions have also been raised about the appropriateness of the body mass index for assessing obesity in patients with end-stage liver disease.
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TRENDING ARTICLES
Missed our previous issues? See which articles your colleagues read most.

    Some receive unnecessary prioritization for liver transplantation, study says (Medical Xpress)
Donor hemodynamic profile presages graft survival in donation after cardiac death liver transplantation (Liver Transplantation (login required))
Study: Prerecovery liver biopsy in the brain-dead donor (Liver Transplantation (login required))
Obese patients with diabetes face higher liver transplant morbidity (Healio)

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ASTS NewsBrief
Colby Horton, Vice President of Publishing, 469.420.2601
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