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Treatment for hypothyroidism during pregnancy may not improve cognitive function in children
Endocrine Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Children of women who were treated for hypothyroidism during pregnancy had similar IQ results at age 3 years as children of women who were not treated, according to recent results. The trial was conducted to build on previous evidence that children born to women with low thyroid hormone levels have decreased cognitive function. More

Use of radioiodine ablation for thyroid cancer has increased and varies inexplicably among hospitals
Clinical Thyroidology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Radioactive iodine-131 has been administered after thyroidectomy for differentiated thyroid cancer for half a century to eliminate residual thyroid tissue and possible metastatic disease. After initial surgery, the indications for radioiodine ablation have not been rigidly defined, leading to considerable variability in its use. The purpose of this study was to determine possible change in practice patterns and the degree to which hospitals in the United States vary in their use of radioactive iodine ablation and the factors that contribute to these variations. More

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Determining which thyroid cancer patients are at low risk for cancer recurrence
Clinical Thyroidology for Patients    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Patients with thyroid cancer initially undergo surgery to remove the thyroid. This may be followed by radioactive iodine therapy. Because only a relatively few patients will die of thyroid cancer, the main risk is for cancer recurrence. Identification of patients at high risk for cancer recurrence would allow more aggressive follow up and treatment. Identification of those patients at low risk would decrease the need for close follow up. The aim of this study was to find out how well testing of patients with thyroid cancer at 8 to 12 months following initial surgery could identify high and low risk patients for cancer recurrence. More

2 commonly available 'third generation' assays for antibodies to the TSH receptor are similar in sensitivity and specificity, but differ in their response to sera containing TSHR-blocking IgGs
Clinical Thyroidology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
How antibodies activate the thyroid-stimulating hormone receptor remains controversial, but it is clear that immunoglobulins that bind to the TSHR and that stimulate adenylate cyclase can be found in the serum of most patients with untreated Graves' disease. This article compared two widely available "third generation" assays for measuring TSHR antibodies. The first assay measures the ability of a patient's serum to stimulate cyclic adenosine monophosphate production in cells transfected to express a synthetic mutant of the human TSHR (two authors are affiliated with the company that markets this assay). The other assay measures the ability of a patient's serum to inhibit the binding of a TSHR-stimulating antibody to an extract of porcine thyroid membranes. More


 
ATA Thyroid Weekly News Briefs
ATA does not develop, exert any editorial or other control, or guarantee the accuracy, completeness, efficacy, or timeliness, of the materials, information, advertising or promotional activities ("Content") in this publication. Inclusion of Content in this publication does not constitute or imply endorsement, agreement, recommendation, or favoring by ATA of such information or the entities mentioned or promoted herein. Use of any Content appearing or referenced in this publication or obtained from advertisers is voluntary, and reliance on it should only be undertaken after an independent review by qualified experts. ATA is not responsible for, and expressly disclaims all liability for, damages of any kind arising out of use of, reference to, reliance on, or performance pursuant to such Content.

Colby Horton, Vice President of Publishing, 469.420.2601
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Julie Bernhard, Sr. Content Editor, 469.420.2647   
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