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Thyroid surgery can reduce snoring, other sleep apnea symptoms
American Thyroid Association    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Obstructive sleep apnea, caused by narrowing or blockage of the airways when a person is asleep affects about 20 percent of the population. Typically a person with OSA will begin snoring loudly on falling asleep. If not treated, obstructive sleep apnea can increase a person's risk of death. It is not clear whether an enlarged thyroid gland, known as a goiter, can worsen cause or worsen symptoms of OSA by compressing the airway. More

Study: OTC thyroid supplements can be dangerous
CBS Money Watch    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A study of over-the-counter thyroid supplements found that several of the products could deliver high doses of thyroid hormones, and in some cases contained more than the human body needs in a day. Investigators in the study bought 10 different thyroid supplements from stores and websites and evaluated their chemical components. Analysis revealed that nine of the supplements contained a hormone called triiodothyronine, or T3, and five of those would deliver at least 50 percent of the total amount of the hormone that the human body produces in a day. Four of the 10 supplements contained a hormone called thyroxine, or T4. Some had twice as much T4 as an adult needs in a day. More

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Management of medullary thyroid cancer remains challenging
Endocrine Today (free registration)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Medullary thyroid cancer is a complex disease that presents unique challenges, speakers said here. Careful consideration of its molecular components and insight into management issues, however, can help clinicians overcome these hurdles. More

Gene mutation increases risk of recurrent papillary thyroid cancer in some patients
American Thyroid Association    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Individuals with advanced papillary thyroid cancer (PTC) that are associated with the BRAFV600E gene mutation have a higher risk of recurrent disease and progression to more advanced, poorly differentiated thyroid cancer, according to data presented at the 81st Annual Meeting of the American Thyroid Association. An understanding of the biological processes that underlie this progression could lead to the development of more effective therapies. More

Screening pregnant women for autoimmune thyroid disease is cost-effective
American Thyroid Association    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Reduced thyroid function during pregnancy can have adverse effects on both the mother and fetus, including increased risk of miscarriage and preterm labor. Thyroid autoimmunity also puts the mother at increased risk of developing postpartum thyroiditis and hypothyroidism in the future. While screening of high-risk women for thyroid dysfunction is recommended, universal screening of pregnant women remains controversial. More


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Treatment of subclinical hypothyroidism is beneficial in women undergoing in-vitro fertilization treatment
Clinical Thyroidology for Patients    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Subclinical hypothyroidism, where there is an increase in serum TSH but normal thyroid hormone levels, is common. However, since many patients with subclinical hypothyroidism do not have any symptoms, it is controversial who should be offered treatement. Pregnant women with hypothyroidism, either subclinical or overt hypothyroidism, are at increased risk of miscarriages and premature deliveries. This is true whether the pregnancy occurs naturally or as a result of in-vitro fertilization. Some studies have shown that treatment of subclinical hypothyroidism during pregnancy helps decrease the risk of miscarriage. The goal of this study was to determine if levothyroxine treatment of infertile women with subclinical hypothyroidism before undergoing in-vitro fertilization would decrease the risk of miscarriage. More

Glitazone pretreatment can boost efficacy of radioiodine therapy in metastatic thyroid cancer
American Thyroid Association    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Repeated radio-ablation therapy with iodine-131 to treat metastatic thyroid cancer can be less effective than the initial round of treatment due to de-differentiation of the cancer cells as the disease progresses, making them less sensitive to I-131. Glitazones, a class of PPARg drugs capable of re-differentiating the cancer cells, can enhance their I-131 uptake. Long-term use of these agents for treatment of diabetes has been linked to cardiovascular side effects. More

Enlarged cervical lymph nodes may signal thyroid cancer
Endocrine Today (free registration)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The appearance of enlarged cervical lymph nodes on ultrasound boosted the predictive value of diagnosing thyroid cancer in suspicious nodules, according to data presented at the 81st Annual Meeting of the American Thyroid Association. Although easy to spot during ultrasonographic assessment of thyroid nodules, the relationship between enlarged cervical lymph nodes and risk for thyroid cancer remains unknown, researchers at the Tulane University School of Medicine in New Orleans said. More

Can nodules with a benign sonographic appearance be left alone without biopsy?
Clinical Thyroidology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There are several published studies that show that a combination of sonographic features such as solid texture, hypoechogenicity, microcalcifications, macrocalcifications, and intranodular vascularity predict that a nodule is more likely to be malignant. Additional studies have shown that some sonographic patterns are associated with benign nodules. It is unclear whether these benign sonographic characteristics are sufficient to justify the decision not biopsying a nodule >1 cm. Bonavita et al. demonstrated that a nodule with four characteristic morphologic patterns (spongiform, cyst with colloid clot, "giraffe" pattern, and "white knight" pattern) were 100 percent specific for benignity. This study tests the reliability of the four sonographic patterns to identify benign thyroid nodules. More


 
ATA Thyroid Weekly News Briefs
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Colby Horton, Vice President of Publishing, 469.420.2601
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Julie Bernhard, Content Editor, 469.420.2647   
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