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Home   Join   Fellows' Corner Nov. 24, 2010

Thyroid hormone levels and bone density in men
Clinical Thyroidology for Patients    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It is well established that thyroid hormones affect bone metabolism. Bone turnover is increased in hyperthyroidism and decreased in hypothyroidism. This suggests that individuals with hyperthyroidism have a lower bone mineral density than people whose thyroid hormones are normal. This lower bone mineral density probably places hyperthyroid patients at a greater risk for osteoporotic fractures of the spine, hips and wrists. Conversely, individuals with hypothyroidism may have a higher bone density and thus be at lower risk for osteoporotic fractures. More

EPA to expand chemicals testing for endocrine disruption
US Environmental Protection Agency    Share    Share on FacebookTwitterShare on LinkedinE-mail
The U.S. Environmental Protection Agency has identified a list of 134 chemicals that will be screened for their potential to disrupt the endocrine system. Endocrine disruptors are chemicals that interact with and possibly disrupt the hormones produced or secreted by the human or animal endocrine system, which regulates growth, metabolism and reproduction. Administrator Lisa P. Jackson has made it a top priority to ensure the safety of chemicals, and this is another step in this process. More

Rehospitalization among elderly patients with thyroid cancer after thyroidectomy are prevalent and costly
Annals of Surgical Oncology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Thyroid cancer increases in incidence and aggressiveness with age. The elderly are the fastest growing segment of the U.S. population. Reducing rates of rehospitalization would lower cost and improve quality of care. This is the first study to report population-level information characterizing rehospitalization after thyroidectomy among the elderly. More

Thyrogen on track after fill/finish revalidation
FiercePharma Manufacturing    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Revalidation of fill/finish equipment caused the delay in Thyrogen shipping that was reported recently, not faulty equipment. The revalidation is standard within good manufacturing practices, says Genzyme spokesperson Erin Emlock. Fill/finish is the only part of Thyrogen production that takes place at Genzyme's Allston Landing site. The cancer treatment is manufactured at a plant in Framingham, Mass., some 20 miles west of the Boston-area facility. More

Managing and treating thyroid cancer
Irish Medical Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Thyroid nodules are quite common in the general population. Nodules may be detected by palpation in up to 5-10 percent of people and by ultra-sonography in up to 50 percent or more. The vast majority (>80 percent) are benign colloid nodules and most are part of a multinodular goiter. Around 15 percent of palpable nodules are benign follicular adenomas. Around 5 percent are thyroid cancers. More

Transient hypothyroxinemia may affect brain development in preterm infants
Clinical Thyroidology for Patients    Share    Share on
FacebookTwitterShare on LinkedinE-mail article
Thyroid hormone is very important for normal brain development. During the third trimester of pregnancy, the baby gets thyroid hormone from the mother as well as its' own thyroid. When a baby is born prematurely, thyroid hormone levels are frequently lower than normal for a period of time then increase back to the normal range (transient hypothyroxinemia). It is unclear whether the effect of this period of low thyroid hormone levels has any effect on the baby's brain development. More

How much does availability of iodized salt improve iodine nutrition?
IDD    Share    Share on FacebookTwitterShare on LinkedinE-mail article
We would expect broader distribution of iodized salt within countries would be associated with better iodine nutrition. A recent study shows that for both developed and developing countries, wider availability of iodized salt is associated with higher median urinary iodine excretion (UI) in school children (one of the more readily available indicators of iodine status). More

Misconceptions and new conceptions about thyroid cancer
Korea Herald    Share    Share on FacebookTwitterShare on LinkedinE-mail
Thyroid cancer is the most common and rapidly increasing cancer in females in Korea since 2007. The reason for the increased prevalence in recent years has not yet been verified. But the development of diagnostic technology is believed to be detecting more cases. About 40 percent of the total population is considered to have a mass in the thyroid gland but just 5 percent of them are thought to be cancerous. More

Utilization of total thyroidectomy for differentiated thyroid cancer in children
Annals of Surgical Oncology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Recent recommendations suggest that total thyroidectomy (TT) is the surgical management of choice for differentiated thyroid cancer in children. The objective of this study is to assess trends in extent of surgical resection for differentiated thyroid cancer in children over the past two decades and to identify patient, tumor or hospital factors associated with use of TT. More
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