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The importance of social support in organ transplantation outcomes
By Maria Frisch
Epidemiological studies have linked poor social support to negative health outcomes and higher mortality rates across a multitude of medical conditions. Social support appears to result in more positive biological profiles, and recent research on immune-mediated inflammatory processes shows how integrative physiological mechanisms directly link social support to physical health. And this asset has been shown to be a key variable in organ transplant success.
5-week-old baby's kidneys successfully used in organ transplant
The Daily Mirror
The kidneys of a five-week-old baby have been successfully transplanted into a woman dying of renal failure, making the infant the youngest organ donor in Britain.
The baby had suffered heart failure after an infection, the Sunday Times reported.
But doctors were able to transplant the tiny kidneys into 22-year-old healthcare assistant Samira Kauser from Halifax, West Yorkshire.
Crossing state lines for an organ transplant
In January 2011, Randy Rosiello, whose son Matthew was born with a rare liver disease, was "watching [her] child die," she told ABC News. "He went from 120 to 85 pounds in a three-month period."
Matthew Rosiello, now 23 and a D.J. in Staten Island, N.Y., was born with biliary atresia. The family, said his mother, spent "every holiday, birthday, anniversary in the hospital." Because Matthew spent so much time there, Rosiello became a nurse.
While biliary atresia often means that a child has a liver transplant before he or she enters kindergarten, Matthew had received no such transplant. One of the problems? He lived in New York state.
For Matthew to survive, figured his mother, they would have to move.
New method may improve face transplant matches
Face transplants — some with remarkable results — are increasingly becoming an option for people with devastating burns and other severe facial injuries. A new study finds that measuring five specific facial landmarks before the surgery may help better match donors and recipients.
"Although there have been many advances made in facial transplantation, reproducible methods of predicting donor-to-recipient match would be very useful, as it can take many months to locate an appropriate donor," study co-author Dr. Bohdan Pomahac said in an American Society of Plastic Surgeons news release.
Young transplant patients 'at higher risk of kidney disease'
Medical News Today
A new national study from U.S. researchers suggests that children who undergo solid organ transplants are at higher risk of developing advanced kidney disease. Researchers from the Children's Hospital of Philadelphia and the University of Pennsylvania say their findings emphasize the importance of continued kidney screening in pediatric transplant patients.
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Widely prescribed statin could help organ-transplant patients
A trawl of existing data has identified drugs that seem to stall organ rejection in patients who have undergone transplants.
By crunching through large, publicly available data sets, researchers pinpointed a suite of genes involved in organ rejection. They were then able to identify drugs that affect the activity of these genes — with candidates including a widely prescribed statin, a class of drug used to lower blood-cholesterol levels. A subsequent analysis of thousands of medical records indicated that statins do in fact help transplant patients.
Researchers create stem cell method that could benefit organ transplants
New healthcare research has developed a method that has enabled scientists to create stem cells for the human liver and pancreas. This could allow both cells to be created for clinical uses such as transplant therapies.
The technique developed within the study will allow researchers to grow original, self-renewing human stem-cells for the first time. These cells are specific to the the upper section of the digestive system known as the foregut.
Pretransplant sensitization against angiotensin II type 1 receptor is a riskfactor for acute rejection and graft loss
American Journal of Transplantation
The angiotensin II type 1 receptor is an emerging target of functional non-HLA antibodies. We examined the potential of determining the degree of presensitization against AT1R as a risk factor for graft survival and acute rejection. The study included 599 kidney recipients between 1998 and 2007. Serum samples were analyzed in a blinded fashion for anti-AT1R antibodies using a quantitative solid-phase assay.
Northern Ireland Assembly Bill on organ donation considered
An MLA is consulting on a private member's bill to give people the option to choose to become an organ donor on their driving licsenses.
Alastair Ross's bill would maintain the current system under which people have to voluntarily express their consent for organ donation.
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