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 Top Stories

Pill-size camera may make cancer diagnosis easier
NHS Choices    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Recent news coverage has heralded the arrival of a new "camera you can swallow" that "could help detect early stages of cancer of the oesophagus." The high-tech device, about the size of a large vitamin pill, uses optical lasers to photograph the insides of the stomach and oesophagus in detail. It is hoped that this new investigative technique may help spot early signs of cancers of the digestive system. More

Pap test could help find cancers of uterus and ovaries
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Pap test, which has prevented countless deaths from cervical cancer, may eventually help to detect cancers of the uterus and ovaries as well, a new study suggests. For the first time, researchers have found genetic material from uterine or ovarian cancers in Pap smears, meaning that it may become possible to detect three diseases with just one routine test. More

Researchers at Stanford University and Intel develop silicon microarray chip capable of producing clinical pathology laboratory test results in minutes
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
At the heart of a new point-of-care technology is a prototype silicon chip that contains up to 9,000 peptides and allows real-time analysis in just minutes. Researchers say this technology can significantly reduce the time-to-answer when compared to existing clinical laboratory testing technologies. This new prototype silicon chip is an on silico peptide microarray. More
Sponsored Content

1st noninvasive test for chromosomal defects in unborn babies
The Inquisitr    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have revealed a new and safer method for detecting chromosomal abnormalities in developing fetuses. According to The American Journal of Human Genetics, a new study shows that the new method — which analyzes fetal DNA in the mother's blood — could even be more informative than more traditional methods, without the risk of miscarriage. More

Researchers identify new genetic mutation for ALS
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Western researchers have identified a new genetic mutation for amyotrophic lateral sclerosis, opening the door to future targeted therapies. Dr. Michael Strong, Schulich School of Medicine & Dentistry dean, and colleagues discovered mutations within the ARHGEF28 gene are present in ALS. When they looked across both familial and sporadic forms of the disease, they found virtually all cases of ALS demonstrated abnormal inclusions of the protein that arises from this gene. More

Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE

 NSH News

NSH launches new portal for tracking continuing education credits
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Over the past year, NSH staff has been working to develop a new portal for tracking continuing education credits (contact hours) that makes life easier for members and nonmembers. The new portal's user friendly design provides 24-hour access to an individual's education records. In addition, the new portal allows histotechnologists access to add hours to their records, eliminating the waiting period after attending a regional or state society sponsored event. Visit to register with the portal. Complete instructions on how to use it can be found on the NSH website.

2013 NSH teleconference/webinar series
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
NSH teleconferences (now available as webinars) are a great, inexpensive way to provide continuing education to a large number of employees. The cost for each session is the same regardless of the number of attendees. The one-hour session is usually held the fourth Wednesday of the month, beginning at 1 p.m. EST. Occasionally, due to holidays, it may be the third Wednesday of the month. More

 In the News

TSRI chemists develop new cell-marking method
The Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemists at The Scripps Research Institute have found an easier way to perform one of the most fundamental tasks in molecular biology. Their new method allows scientists to add a marker to certain cells, so that these cells may be easily located and/or selected out from a larger cell population. More

Cell communication protein may be key to better cancer drugs
University of Georgia via Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly policing the streets, making repairs, building new structures and delivering important cargo throughout the bustling organic society. For everything to work properly there must be something to organize and direct the various workers. Enter protein kinases. More

New SOX-11 (MRQ-58) for MCL!
SOX-11 expression is specific for the identification of cyclin D1 negative mantle cell lymphoma. SOX-11 is useful due to its high expression in cyclin D1 positive and negative MCL. Many B-cell lymphomas can mimic MCL; therefore, it’s important to have additional antibodies to detect cyclin D1 negative MCL. Learn More.
Slimsette™ Recessed Cover Tissue Cassettes
Available in slotted, biopsy and four compartment versions, the Slimsette™ recessed cover allows for use with lids attached during labeling in cassette printers. Part of the full line of cassettes from LabStorage Systems, Slimsette™ comes in convenient dispenser boxes or preloaded in plastic sleeves for automatic printers. MORE
StatClick™ Specimen Transport Vials
We’ve added a click and removed the leak. Turn the lid until it clicks. Ship with confidence that your samples and your reputation will stay perfectly preserved. To learn more, please visit us at: or contact us at 800-442-3573.

Call to contributors
MultiBriefs    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In an effort to enhance the overall content of Under the Microscope, we'd like to include peer-written articles in future editions. As a member of NSH, your knowledge of the industry lends itself to unprecedented expertise. And we're hoping you'll share this expertise with your peers through well-written commentary. Because of the digital format, there's no word or graphical limit and our group of talented editors can help with final edits. If you're interested in participating, please contact Colby Horton to discuss logistics and payment. More

Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE

Major step toward an Alzheimer's vaccine
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team of researchers from Université Laval, CHU de Québec, and pharmaceutical firm GlaxoSmithKline has discovered a way to stimulate the brain's natural defense mechanisms in people with Alzheimer's disease. This major breakthrough, details of which are presented in an early online edition of the Proceedings of the National Academy of Sciences, opens the door to the development of a treatment for Alzheimer's disease and a vaccine to prevent the illness. More

Cancer biology: Keeping bad company
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. Even worse, however, are the various "missense" mutations that change the amino acid sequence of p53: They warp its function to promote rather than prevent cancer. More

Cell biology researchers look to future
The Stanford Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the Stanford Covert System Biology Lab recently developed the world's first whole-cell model of all the biological processes in a cell, which can be used to educate medical decisions, such as allowing for more detailed prognoses delivered to patients. The team developed a model of Mycoplasma genitalium, a small bacterium. They will work on a similar whole-cell model for E. coli over the next year, which they expect to attract the attention of the biofuel community. More

Biomaterial improves knee cartilage repair
Johns Hopkins University via Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a hydrogel scaffolding into the wound to support and nourish the healing process. The squishy hydrogel material was implanted in 15 patients during standard microfracture surgery, in which tiny holes are punched in a bone near the injured cartilage. The holes stimulate patients' own specialized stem cells to emerge from bone marrow and grow new cartilage atop the bone. More

Get your histology CE from MediaLab

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Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
EndNote X6
EndNote® enables you to move seamlessly through your research process with flexible tools for searching, organizing and sharing your research, creating your bibliography and writing your paper. New in X6: Access your research from anywhere and manage your EndNote library from multiple computers with the new EndNoteSync.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Content Editor, 469.420.2642   
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