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Replace Messy Ice Baths

Cool to -60C. Heat to +150C. Designed for laboratory use, TECA cold/hot plates offer convenient thermal control of samples in histology and life sciences applications.



The 2014 Lab Webinar Series starts with NSH IHC Committee Chair, Joe Myers, CT(ASCP)QIHC
Register for next Wednesday's webinar, Jan. 22, titled "Immuno-Staining Cytologic Specimen Material: Practical Considerations and Potential Pitfalls" presented by NSH's very own IHC Committee Chair. This webinar is intended to provide participants with a comprehensive overview of the procedures involved in immune-staining cytologic (i.e., loosely cellular) specimen material — including smears, fine-needle aspirates, Cytospin™ preparations, "monolayer" preparations, and cell blocks prepared using traditional and newly developed methods/devices. Read more.
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The $1,000 genome arrives — for real, this time
Recently, Illumina, the leading maker of DNA sequencers, announced a milestone in biotechnology: it is introducing a new machine that can sequence the genetic code of a human cell for $1,000. The machine — actually a combination of 10 machines working together called the HiSeqX Ten — will cost $10 million. Already, three have been bought by Macrogen, The Harvard-MIT Broad Institute in Cambridge, and the Garvan Institute of Medical Research in Australia. Illumina forecasts that it will sell five of the systems this year.
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Custom-fit teatments for prostate cancer
The Wall Street Journal
In a bid to improve treatment for men with high-risk prostate cancer, some researchers want to take a page from the playbook for breast cancer. Medical scientists are working to develop strategies for treating prostate tumors that are tailored to individual patients, as is currently done for many women with breast cancer. Fresh advances in the understanding of prostate cancer suggest that some men with a high-risk form of the disease might benefit from more aggressive treatment.
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Smart gels deliver medicine on demand
R&D Magazine
Researchers at the University of Delaware have developed a "smart" hydrogel that can deliver medicine on demand, in response to mechanical force. Over the past few decades, smart hydrogels have been created that respond to pH, temperature, DNA, light and other stimuli. "The idea of a smart hydrogel that can release medicine over time is not new," said Xinqiao Jia, UD professor.
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  Reduce Cost with Same Quality

GBI Labs produces the largest selection of secondary detection kits. We provide free samples to 1st time users. Staining with our kits results in similar or better sensitivity than other detection kits on the market. Some 110mL kits cost as little as $700.00 and 18 ml kit > $300.00.

Understanding of epigenetics deepens
Genetic Engineering & Biotechnology News
As epigenetics is unveiling new layers of organization and regulation, it is becoming increasingly clear how little we knew about fundamental processes shaping biological systems. Many transformative changes from virtually every biomedical discipline owe their existence to epigenetics. The development of new technologies and the refinement of the existing ones are marking an era when, in addition to introducing new concepts, we are also revisiting, and often reshaping, many of the existing ones.
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Unwanted side effect becomes advantage in photoacoustic imaging
R&D Magazine
Biomedical engineer Lihong Wang, Ph.D., and researchers in his laboratory work with lasers used in photoacoustic imaging for early cancer detection and a close look at biological tissue. But sometimes there are limitations to what they can do; and as engineers, they work to find a way around those limitations.
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ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
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To find out how to feature your company in Under the Microscope and other advertising opportunities, Contact Geoffrey Forneret at 469.420.2629

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New aspirin-based prodrug may prevent damage caused by chemotherapy
Medical Xpress
Researchers at the University of Georgia have developed a new prodrug that promises to reduce many of the negative side effects caused by cisplatin, a commonly prescribed chemotherapy treatment. Cisplatin may be used to treat a variety of cancers, but it is most commonly prescribed for cancer of the bladder, ovaries, cervix, testicles, and lung. It is an effective drug, but it often causes severe and irreversible damage to a patient's kidneys, hearing, and sense of balance.
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Novel tomography system may help guide therapy in early breast cancer
Diffuse optical tomography is a novel, fast, safe and low-cost technique that uses near-infrared light to provide 3-D data on tissue vascularity without the use of radiation. Columbia University oncologists have been studying whether a system developed at the university can help guide physicians in evaluating chemotherapy and antiangiogenic treatment options for patients with early breast cancer. Andreas H. Hielscher, Ph.D., a professor of biomedical engineering, electrical engineering, and radiology at Columbia, has designed a digital continuous wave system that images both breasts at the same time at fast-frame rates, with a large number of sources and detectors.
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Caught in the act: microbes do have sex
The Conversation
There is no denying that humans think sex is important, but it also matters for microbes. Sex allows genes from two parents to be mixed, leading to new combinations of genes in the offspring. In the past, many disease-causing protozoa were thought to reproduce by splitting in half with no genetic exchange, which is the common way that most microbes reproduce. But new results show they also use sex to swap genes between strains.
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Systemic and comprehensive genomic study of cervical cancer completed
Medical Xpress
Chromosomes are heavily adorned with methyl chemical groups that alter the activity of nearby genes. The parental chromosomes, contributed by sperm and egg, display distinctly different methylation patterns and most modifications are stripped away shortly after fertilization. However, a subset of these 'imprints' are protected. Now, a sophisticated technique for single-cell analysis has broadened the understanding of this process.
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Want to get published?
In an effort to enhance the overall content of Under the Microscope, we'd like to include peer-written articles in future editions. As a member of NSH, your knowledge of the industry lends itself to unprecedented expertise. And we're hoping you'll share this expertise with your peers through well-written commentary. Because of the digital format, there's no word or graphical limit, and our group of talented editors can help with final edits. If you're interested in participating, please contact Ronnie Richard to discuss logistics.
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Missed last week's issue? See which articles your colleagues read most.

    Chemical imaging brings cancer tissue analysis into the digital age (R&D Magazine)
New finding has major implications for genetic testing as researchers learn that greater numbers of humans have multiple personal genomes (Dark Daily)
Israeli researchers create tiny, programmable, genetic test device that can roam the body and diagnose and treat diseases on the spot (Dark Daily)
Researcher explores link between flame retardants and thyroid cancer (Medical Xpress)
Leaked files slam stem-cell therapy (Scientific American)

Don't be left behind. Click here to see what else you missed.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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