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Bioengineers '3-D print' living human embryonic stem cells for 1st time
3-D printing technology is achieving remarkable things of late — most especially in the fields of biomedicine and cell biology. And while bioengineers have succeeded in printing embryonic (mouse) cells via similar technology, the "holy grail" of cell printing — the printing of living embryonic stem cells from human cells — has remained unfulfilled... until now.
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Scientists build harness for powerful radiation cancer therapy
R&D Magazine
Low-energy radiation particles, known as beta particles, are often used in radiation treatments for cancer patients. For years, scientists have been studying how to use alpha particles, which are far higher in energy, for the same treatments. The challenge has been finding ways to focus these powerful particles on target cancers without hurting other tissues. A collaboration of scientists have recently created a gold nanoparticle that can transport powerful alpha particles directly to tumors for treatment.
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Sponsored Content

New study shows bio-electric signals can nip cancer in the bud
A bio-electric signal can identify cancer prone cells and potentially suppress their growth by the manipulation of the electrical charge across their membranes, according to a study. "The discovery helps establish a bio-electric basis for the early detection of cancer," said Brook Chernet, doctoral student who co-authored the study with Michael Levin, professor of biology and director of the Centre for Regenerative and Developmental Biology at the Tufts University.
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Printed organs may eliminate transplant problems
Heriot-Watt University via Laboratory Equipment
A specialized 3-D printing process, using human stem cells, could pave the way to purpose-built replacement organs for patients, eliminating the need for organ donation, immune suppression and the problem of transplant rejection. The process, developed at Heriot-Watt University, in partnership with Roslin Cellab, takes advantage of the fact that stem cells can now be grown in laboratory conditions from established cell lines, could also speed up and improve the process of drug testing by growing 3-D human tissues and structures for pharmaceuticals to be tested on.
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Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE

NSH News

Histotechnology Professionals Day
Histotechnology Professionals Day is only a month away. Visit the NSH website to participate in this year's contest to win great prizes.

We also have fun things for sale to help promote the profession. Visit the NSH store or download HPD form.

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In the News

Blood vessel cells coax colorectal cancer cells into more dangerous state
Bioscience Technology
Blood vessels that supply oxygen and nutrients to tumors can also deliver something else — a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at The University of Texas MD Anderson Cancer Center reported. Working in human colorectal cancer cell lines and tumor samples, as well as mouse models, the researchers found that endothelial cells, which line the inside of blood vessels, can trigger changes in cancer cells without even coming into direct contact with them.
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New SOX-11 (MRQ-58) for MCL!
SOX-11 expression is specific for the identification of cyclin D1 negative mantle cell lymphoma. SOX-11 is useful due to its high expression in cyclin D1 positive and negative MCL. Many B-cell lymphomas can mimic MCL; therefore, it’s important to have additional antibodies to detect cyclin D1 negative MCL. Learn More.
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
StatClick™ Specimen Transport Vials
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Cells lose ability to defend against transposons as they age
The Medical News
Even in our DNA there is no refuge from rogues that prey on the elderly. Parasitic strands of genetic material called transposable elements — transposons — lurk in our chromosomes, poised to wreak genomic havoc. Cells have evolved ways to defend themselves, but in a new study, Brown University researchers describe how cells lose this ability as they age, possibly resulting in a decline in their function and health.
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Japanese scientists develop new method for intracellular temperature mapping
The team exploring the functions of mRNA — a molecule that encodes the chemical blueprint for protein synthesis — has been able to show the actual temperature inside living cells. The breakthrough may lead to a better understanding of diseases, such as cancer, which generate extraordinary intracellular heat. Conventional temperature imaging methods lack spatial resolution and sensitivity, which means these methods are incapable of imaging extremely tiny temperature differences inside living cells.
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Sensitive and specific 2-plex RNA-ISH assay

Affymetrix’ QuantiGene® ViewRNA Assays enable single-copy RNA sensitivity with exceptional specificity in FFPE tissue sections. From sequence to assay in 1 week. View recent publications.
Milestone was founded in 1988 as a company specializing in advanced microwave instrumentation for analytical and organic chemistry labs. MORE

Quantum physics sheds light on cells
ABC Science
For the first time, Australian scientists have explored the inner workings of a living cell using a new kind of laser microscopy that harnesses the laws of quantum physics. The technique could shed light on new biological processes, the motion of microscopic particles, and even allow quantum mechanics to be studied at a scale visible to the naked eye, says the study's lead author, physicist Dr. Warwick Bowen from the University of Queensland.
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Cells 'flock' to heal wounds: Research team analyzes physics of epithelial cell cooperation
Rice University via PhysOrg
Researchers once thought only the cells at the edge of a growing patch of wounded skin were actively moving while dividing cells passively filled in the middle. But that's only part of the picture. Rice University physicist Herbert Levine and his colleagues have discovered that the process works much more efficiently if highly activated cells in every part of the patch exert force as they pull their neighbors along.
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Missed last week's issue? See which articles your colleagues read most.

    Cancer researchers find progress in glowing mice (The Daily Tar Heel)
SLU researchers: Vitamin D holds promise in battling a deadly breast cancer (
High-tech images show how viruses infect cells (Voice of America)
Computer-assisted diagnostics systems may help improve utilization of clinical pathology laboratory tests (Dark Daily)
Opening a new avenue in neurobiology, scientists turn 1 form of neuron into another in the brain (Harvard University via PhysOrg)

Don't be left behind. Click here to see what else you missed.

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Stellaris RNA FISH Probes

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Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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