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TOP STORIES

Biologists find key to new anti-malarial drug
Deutsche Welle
Australian researchers say they have found the key to a new anti-malarial drug, which kills the parasite responsible with a salt overdose. It's the first new discovery in the fight against malaria in 20 years. Professor Kiaran Kirk and his team at the Australian National University worked with researchers from the United States and Singapore to discover the mechanism which makes the new drug work. He said that understanding this will enable researchers to track its long-term effectiveness and to detect whether the malaria parasite is able to develop resistance.
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11 scientists getting $33 million from Mark Zuckerberg, Sergey Brin, and the Silicon Valley elite
Fast Company
Recently, some of the fantastical predictions made by Silicon Valley at the FutureMed conference about what the future of healthcare will look like were reviewed — things like viruses that cure cancer, real-time brain monitoring and dogs that sniff out disease. Some of these predictions are tantalizingly close, if only scientists had the funding to explore them. So a large swath of the Silicon Valley elite — Art Levinson, Sergey Brin, Anne Wojcicki, Mark Zuckerberg, Priscilla Chan and Yuri Milner — are teaming up to give $3 million each to 11 scientists working on "research aimed at curing intractable diseases and extending human life."
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Sponsored Content


Brilliant X-rays light up dangerous viruses in detailed 3-D
Medical News Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Diamond Light Source, the U.K.'s national synchrotron facility, is launching a new lab to study the detailed atomic and molecular structures of dangerous viruses and bacteria, including those that cause serious diseases such as AIDS, hepatitis and some types of flu. Studying the detailed structures of pathogens in this way can help the development of new treatments and vaccines. More

Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE


Mini microscopes see inside the brains of mice
NBC News
Mini microscopes embedded into the brains of genetically engineered mice are providing researchers a window onto the inner workings of the mammalian mind. The tool provides an unprecedentedly wide field of view on the mouse brain — in one mouse, for example, the team recorded the firing of more than 1,000 individual neurons — and it can record for weeks on end, allowing scientists to study how brain activity evolves over time.
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Spring Bioscience - BRAF V600E


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IN THE NEWS


Treat sickle cell with an antidepressant?
Futurity
A drug used as an antidepressant since the 1960s can essentially reverse the effects of sickle cell disease, according to a new finding made in mice and human red blood cells. Scientists made the discovery about the drug tranylcypromine, or TCP, after more than three decades studying the basic biology of the condition. Their findings pave the way for a clinical trial now being planned for adult patients who have the life-threatening condition. The discovery also may lead to other treatments for the disease, which leads misshapen red blood cells to cause vascular damage and premature death.
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Biologists create 'zombie cells' in the lab ehich outperform living counterparts
The Huffington Post UK
Biological researchers have created dead "zombie" cells in the lab that outperform living cells. Seriously. A team at Sandia National Laboratories and the University of New Mexico have innovated a technique whereby mammalian cells are coated with silica to form a near-perfect replicas. The silica replicants can survive greater pressures and temperatures than flesh, and perform many functions better than the original cells did when alive.
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Molecules generated that can halt metastasis of colon cancer
Science Codex
A Basque research consortium has managed to halt the progress of colon cancer and its metastasis in the liver in an experimental model with mice. This advance, that may open a new path for the future treatment of such pathologies, has been achieved by creating molecules which interfere with the adhesion of tumor cells to other cells of the organism. In this way, the molecules halt both the growth of the tumor and the dissemination of the tumor to and its proliferation in other organs.
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Researchers gain insight into abnormally shaped cell nuclei of people with cancer
Northwestern University via Medical Xpress
Researchers at Northwestern University have recently developed a mathematical model that sheds light on the defect by clarifying the mechanisms that cause bulges known as "blebs" in cells' nuclear membranes. The research — a collaboration between experts at the McCormick School of Engineering and Applied Science and the Feinberg School of Medicine — could be a step toward bleb prevention, which may ultimately provide potential therapies for related diseases.
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  Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE
 


Researchers identify new role of Sp2 protein
Technician
From allowing us to breathe to helping fight infection, protein molecules keep us healthy, but research over the past several decades has shown that proteins only keep us healthy if produced in the right quantity. Protein, a special type of molecule found in food and produced by the human body, plays a key role in our biological processes, but any more or any less of the right amount of different proteins, and we get different diseases.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Combining synthetic and natural toxins could disarm cancer, drug-resistant bacteria (The Medical News)
Researchers identify taste stem cells (Sci-News.com)
New ways to fund science: Geneticist, panel discuss how research and public interest can intersect (Harvard University via PhysOrg)
How a mushroom can beat the illness of old age (Business Day)
Diabetes treatment: Stem cells show potential (The California Aggie)

Don't be left behind. Click here to see what else you missed.


From 3-D cell culture to DNA repairs
Lafayette Journal & Courier
A Purdue University scientist will continue his research with DNA repair after receiving a Howard Temin Pathway to Independence Award. The award provides two years of mentored support and up to three years to conduct research as an independent scientist. No other researcher has received this award while at Purdue. Vidi's research uses 3-D cell culture to reproduce mammary gland tissues and breast cancer to study DNA repair in relevant contexts. Vidi said that by understanding how DNA is repaired, one can potentially make cancer cells easier to treat, while allowing the normal tissue to repair itself and withstand cancer.
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Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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