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National Medical Laboratory Professionals Week
Congratulations to all histotechnologists, pathologists and other laboratory professionals. NSH wants to thank you for your dedication to the vital role you play in every aspect of healthcare. NMLPW is a time to celebrate your professionalism and to inform and educate medical colleagues and the public about the impact your role has on the overall patient care. Have a great week of celebration!
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CAP and NSH release new guideline to improve patient safety
Today, the College of American Pathologists and the National Society for Histotechnology released the first evidence-based guideline to ensure patient safety through the uniform labeling of paraffin blocks and slides. The guideline, "Uniform Labeling of Blocks and Slides in Surgical Pathology," is now available in the online edition of Archives of Pathology & Laboratory Medicine.
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May 27 laboratory webinar
Presented by Ada Feldman, MS, HT/HTL(ASCP), Anatech, Ltd., Battle Creek, Michigan
"Why Does the H&E Staining Look Different Today?"

Register now.

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How wearables and mobile health tech are reshaping clinical trials
Life science companies are continuously looking for ways to advance clinical research while simultaneously improving the understanding of drugs they are developing. One of the biggest issues for researchers is the high failure rate of new drugs during clinical development. The stakes are high in a global pharma market that is expected to exceed $1.2 trillion by 2018.
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Studies show how clinical whole-exome sequencing may forever change the future practice of medicine while giving pathologists a new opportunity to deliver value
Dark Daily
In recent years, pathologists and other clinical laboratory professionals have seen increasing evidence of the benefits of using exome sequencing for clinical diagnostic purposes. Confirming their initial published findings of a 25 percent molecular diagnostic rate, researchers from Baylor College of Medicine, Baylor Human Genome Center, and the University of Texas Health Science Center at Houston have released results of a large sampling of 2,000 consecutive patients.
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Wisconsin researcher predicts cancer will be chronic disease in 10-15 years
Grand Forks Herald
The world of cancer research is changing, according to University of Wisconsin-River Falls professor Tim Lyden. "There's a real revolution happening in cancer biology right now," Lyden said. "I think in 10 or 15 years, cancer is going to be a very different disease. Probably a lot of cancers will be changed to chronic disease rather than the life-threatening kind of diseases that he yare today. It doesn't mean that we're going to cure all of them or necessarily cure any of them outright, but I think we are going to develop much better understandings."
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New kidney disease findings may lead to test for early diagnosis
Medical News Today
New findings from scientists at The University of Manchester in the U.K. may provide the basis for an early test for kidney disease. The researchers were investigating why some groups are more susceptible to kidney disease than others. For instance, impaired kidney function is more common among men than women and among black people than white people.
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    Are CLIA inspections of clinical pathology labs getting tougher? Why it pays to achieve 'inspection readiness'
    Dark Daily
    Recent reports indicate that regulatory inspections of clinical laboratories are getting tougher. Some pathologists and medical lab managers acknowledge that they've had to scramble in response to the unexpected deficiencies identified by Clinical Laboratory Improvement Amendments inspectors following inspections of their labs.
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    Pre-clinical model reveals pathology behind mitochondrial disease
    Science Network WA via Medical Xpress
    A lack of a particular mitochondrial protein in genetically manipulated mice has shown to trigger events in the body that causes mild heart hypertrophy (enlargement) and severe fatty liver disease. Mitochondria are organelles found in every cell of the body. They have their own set of genes and are responsible for energy production. Mitochondrial disease is complex, most often caused by a defect in mitochondrial protein formation which impairs the energy generating machinery and makes patients suffer from a shortage of energy.
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    Team shows how blood-brain barrier is maintained
    University of Pennsylvania via Medical Xpress
    The brain is a privileged organ in the body. So vital to life, the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected molecules to pass through. In certain diseases, however, such as multiple sclerosis, the barrier can be improperly breached. These "leaks" can allow immune cells and inflammatory molecules to pass through, causing inflammation that leads to neuronal damage.
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    Could a nonprescription antifungal become a major advance for multiple sclerosis?
    Scientific American (blog)
    In 2011, Paul Tesar, a professor at Case Western Reserve School of Medicine, worked with collaborators to come up with a method of producing massive numbers of mouse stem cells that are capable of turning into oligodendrocytes, the cells that produce myelin, the protective coating on nerve cells. One thing you can do with such a technique, assuming you can do the same thing with human cells, is to use biochemical legerdemain to restore the myelin lost in multiple sclerosis, cerebral palsy and other disorders. But cell replacement therapies are still a work in progress—and may continue to be so for a long time
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    Missed last week's issue? See which articles your colleagues read most.

        NSH webinar IHC for Leukemia/Lymphomas presented by Dr. Madhu Menon, PhD, Henry Ford Hospital, Detroit (NSH)
    Registration for Annual Symposium/Convention open (NSH)
    Peer-review scandals shake up scholarly journal community (By Cait Harrison)
    Clinical labs and research organizations are racing to get low-cost, handheld DNA analyzers to market (Dark Daily)
    Managing millennials — it's their generation now (Lab Manager)

    Don't be left behind. Click here to see what else you missed.

    Under the Microscope
    Colby Horton, Vice President of Publishing, 469.420.2601
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