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Happy Lab Week!
This week is an annual celebration of what you do each and every day. We want to thank you all for your hard work and for playing a vital role in every aspect of healthcare. We know you work behind the scenes, but make sure this week you set aside some time to celebrate you and let people know how proud you are to be a laboratory professional. Click here for full information about Lab Week from ASCP.
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The NSH IHC/Molecular Forum is coming out west to Las Vegas
In its sixth year the IHC/Molecular Forum program team has created a two-day slate of general sessions and workshops for the intermediate to advanced attendee. Each day features a track of workshops dedicated to both the clinical and research arenas. The forum is a great value for your training dollars featuring 12 expert speakers, offering 12 continuing education credits for one low price. Spend your Monday and Tuesday choosing workshops that fit your needs, and enjoy your nights at the Las Vegas casinos and shows! Click here to register online or view the PDF registration form here.
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Is there a link between prostate cancer and chronic inflammation?
Based on data from a new study at the Johns Hopkins Kimmel Cancer Center, men who demonstrate evidence of chronic inflammation seen in prostate biopsies stemming from chronic prostatitis may have close to twice the risk of developing prostate cancer compared to those without inflammation. Prostate cancer is the second most common cancer in men in the US.
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Stem cell culture growth improved by Silly Putty
Liberty Voice
Who would have thought? By experimenting with an ingredient in Silly Putty, a popular children's toy, researchers have improved on the substrate media normally used for growing embryonic stem cells in culture. In addition to a number of other factors, growth of human embryonic stem cells is affected by the texture of the surface on which they are growing.
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  New Rabbit Monoclonals from Epitomics

Introducing our recently launched EP clones developed specifically for anatomical pathology. Epitomics has the largest catalogue of diagnostic grade rabbit monoclonals, with over 230 unique targets. Some of our recently launched EP clones include ARG-1, PAX-2, SOX-10, CD2, TBX21 and more. Our recent 2014 Catalogue is available here.

Standard drugs for Huntington's may be detrimental
San Diego Jewish World
People diagnosed with Huntington's disease, most in their mid-30s and 40s, face a devastating prognosis: complete mental, physical, and behavioral decline within two decades. "Mutant" protein clusters, long blamed for the progression of the genetic disease, have been the primary focus of therapies in development by pharmaceutical companies. But according to new research from professor Gerardo Lederkremer and Dr. Julia Leitman of Tel Aviv University's Department of Cell Research and Immunology, in collaboration with professor Ulrich Hartl of the Max Planck Institute for Biochemistry, these drugs may not only be ineffective — they may pose a serious threat to patients.
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Penn Vet researcher makes progress toward controlling viral diseases
Penn Current
The Ebola outbreak in West Africa has claimed more than 140 lives in recent months. The disease is a frightening one, with fatality rates that can approach 90 percent and no effective vaccine or cure. A pair of recent studies by the School of Veterinary Medicine's Ronald Harty, an associate professor of microbiology, offer hope that Ebola and other viral diseases, including HIV and rabies, may one day be treatable by broad-spectrum antiviral drugs.
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Empowering Science with Color Integrity

Datacolor CHROMACAL™ standardizes color reproduction in digital brightfield images.

• Delivers a consistent, reliable basis for evaluation, communication, quantification, documentation and publication
• Includes image and monitor calibration software, along with a proprietary color calibration slide
• Integrates into existing imaging workflow
• Compatible with most microscopes, scientific cameras and acquisition software

NanoMolds™ Save Time, Energy & Money

NanoMolds produce paraffin blocks much quicker and release easier than traditional methods – without the use of messy chemical mold release.

  • Requires less cleaning
  • Easier & Faster block
  •     release
  • Faster creation of the block
  • Available in 5 popular sizes

  • Call Sakura at 800-725-8723 for more information
    ergoCentric Laboratory Seating

    Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more


    Adult stem cell research shows promise
    U.S. Food and Drug Administration
    Scientists sporting white coats and safety gloves are working in a bright Food and Drug Administration lab on an incredible project. They are part of FDA's MSC Consortium, a large team of FDA scientists studying adult mesenchymal stem cells — cells that could eventually be used to repair, replace, restore or regenerate cells in the body, including those needed for heart and bone repair.
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    Genes may predict the need for further cancer treatments
    Oncology Nurse Advisor
    A new predictive tool is being developed that could help patients with breast cancer and certain lung cancers decide whether follow-up treatments are likely to help. Jerry Shay, Ph.D., vice chairman and professor of cell biology at University of Texas Southwestern in Dallas, led a three-year study on the effects of irradiation in a lung cancer-susceptible mouse model. When his team looked at gene expression changes in the mice, then applied them to humans with early stage cancer, the results revealed a breakdown of which patients have a high or low chance of survival.
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    From liability to viability: Genes on the Y chromosome prove essential for male survival
    Despite a well-documented history of dramatic genetic decay, the human Y chromosome has over the course of millions of years of evolution managed to preserve a small set of genes that has ensured not only its own survival but also the survival of men. Moreover, the vast majority of these tenacious genes appear to have little if any role in sex determination or sperm production. Taken together, these remarkable findings suggest that because these Y-linked genes are active across the body, they may actually be contributing to differences in disease susceptibility and severity observed between men and women.
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    Missed last week's issue? See which articles your colleagues read most.

        NSH Laboratory Webinar: Immunohistochemistry Staining for Orphan Metastic Tumors (Metastasis from Unknown Primary) (NSH)
    7th Annual Summer Symposium — Baltimore (NSH)
    Study examines biomarkers in HPV negative squamous-cell carcinomas of the head and neck (redOrbit)
    Sharpening microscope images: New technique takes cues from astronomy, ophthalmology (Fars News Agency)
    Excluding drug companies from drug information dissemination (By Mike Wokasch)

    Don't be left behind. Click here to see what else you missed.

    Protein expression gets the heart pumping
    Baylor College of Medicine
    Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, researchers at Baylor College of Medicine have now been able to categorize the alternative splicing (the process in which genes code proteins, determining their role) that takes place during these changes and what mechanisms they affect.
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    Looking for similar articles? Search here, keyword PROTEINS.

    More sensitive testing may better define prognosis and treatment
    for leukemia

    Oncology Nurse Advisor
    Nearly half of patients with the most common form of adult leukemia are said to have normal chromosomes but appear instead to have a distinct pattern of genetic abnormalities that could better define their prognosis and treatment. These findings were presented during the American College of Medical Genetics and Genomics Annual Clinical Genetics Meeting in Nashville, Tenn. Using microarray technology that probes millions of genes within chromosomes, researchers found the unique pattern in the leukemia cells of 22 patients with cytogenetically normal acute myelogenous leukemia, said Ravindra Kolhe, MD, PhD, molecular pathologist at the Medical College of Georgia at Georgia Regents University in Augusta.
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    Cultured red blood cells: There's nothing artificial about it
    By Rosemary Sparacio
    Blood transfusions play a critical role in clinical practice. Over 90 million transfusions take place each year. Transfusions are made possible throughout the U.S by donations from individuals, blood-donor programs, blood banks and the American Red Cross. However, in order to get the supplies they need, all venues must participate. Unfortunately, that is not always the case. The relatively short lifespan of donated blood, which is 120 days, demands that there is always a constant fresh supply. And even though there are testing parameters in place, there is always the risk of transmitting infections and the potential for incompatibility issues between donor and recipient.
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    Under the Microscope
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