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Human brain cells developed in lab, grow in mice
University of California, San Francisco via Medical Xpress
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat people with Parkinson's disease, epilepsy and possibly even Alzheimer's disease, as well as complications of spinal cord injury such as chronic pain and spasticity.
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Looking for similar articles? Search here, keyword STEM CELL RESEARCH.

Health insurers spending big dollars to be players in 'big data,' trend has implications for clinical pathology laboratories
Dark Daily
Faced with swift changes in healthcare, many of which are not favorable to the traditional business model of private health insurers, the nation's largest payers are positioning themselves to be major players in the management of "big data." That may have interesting implications for clinical laboratories and anatomic pathology groups, which typically generate large quantities of medical laboratory test data.
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Scientists discover a brain region that controls aging
Bloomberg Businessweek
Scientists at the Albert Einstein School of Medicine say they've discovered a brain region that may control aging throughout the entire body. By manipulating that region, they were able to extend the lives of mice by 20 percent. The finding, detailed in a paper published in Nature on May 1, may lead to new ways of warding off age-related diseases and increasing life spans.
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Discovery helps show how breast cancer spreads
Washington University in St. Louis
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis.
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  Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.

Researchers develop new technique to track cell interactions in living bodies
Researchers at Stanford University School of Medicine have developed a new technique to see how different types of cells interact in a living mouse. The process uses light-emitting proteins that glow when two types of cells come close together. Using the technique, the team was able to pinpoint where in the body metastatic cancer cells ended up after they broke off from an initial tumor site, using readily available lab reagents.
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Awards and scholarships
Celebrate the value, leadership and influence of your peers in the histology profession. NSH scholarships are available for members to further their education. Most scholarships are available for those working in general histology, however the program does offer some specialized scholarships for those working in niche areas of the science. The money can be used for tuition, event registration fees, books and more.
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The NAACLS board of directors is requesting public comment for a proposed change to 2012 HTL Standard 7A1B and 2012 HTL Standard 7B1B (Click here to download). This change will allow both HTL(ASCP) and HT(ASCP) certifications to be acceptable for program directors and education coordinators of NAACLS Accredited HTL programs, as recommended by the Review Committee for Accredited Programs. This period of public comment has been made available for 30 days. Responses may be directed to Edward Rotchford.
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RNAscope: Visualize Single-Copy RNA

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StatClick™ Specimen Transport Vials

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Research discovery may lead to effective new treatments for neurodegenerative disease
The Medical News
UCLA researchers led by Drs. Peiyee Lee and Richard Gatti at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have used induced pluripotent stem cells to advance disease-in-a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia. Their discovery shows the positive effects of drugs that may lead to effective new treatments for the neurodegenerative disease.
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5 keys to successful research collaborations
By Mike Wokasch
Goals, objectives and circumstances often dictate whether competition or collaboration will produce better results, faster. At the same time, academic groups working in the same disease or therapeutic area would benefit from collaboration rather than competition. Funding is competitive process and, obviously, the rewards for success don't have to be shared. On the other hand, many of these types of research programs are trying to figure out the same thing, answer the same questions and develop the same type of products.
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Industry Pulse: Which is a more effective research strategy?

Visualize ANY RNA in situ
QuantiGene® ViewRNA Assays enable single-molecule RNA detection in cells, CTCs, tissues and TMAs. Same slide can be visualized under bright field and fluorescence. Learn more.
Milestone was founded in 1988 as a company specializing in advanced microwave instrumentation for analytical and organic chemistry labs. MORE

Czech scientists make mice cells glow different colors to advance genetic research
Deutsche Welle
Beyond some well-protected doors, in sterile conditions off limits to casual visitors, laboratory mice and rats have been injected with stem cells and other genetic material to induce tiny genetic modifications. Using colored proteins obtained from sea organisms like coral, Dr. Radislav Sedlacek and his team can literally light up the mice under a special camera and observe how a cell is developing with a particular gene switched off — without having to kill the animal first.
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  Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE

Scientists make human bone from skin cells
Medical Daily
Human bone grown in a laboratory dish has been successfully transplanted into living mice, according to a study published in the Proceedings of the National Academy of Sciences. The successful transplant represents an important step in the effort to repair human bones. In the past, scientists have approached the problem of repairing human bones by using synthetic materials or bone transplants, techniques that so far have produced limited results.
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  Hu-on-Hu & Ms-on-Ms Ab Detection

Klear Human
(D103) for Clinical or Pharmaceutical screens of Humanized or Hu-Antibody on human tissues and Klear Mouse (D52) for screening mouse models (transgenic or xenografts) using Ms-Antibody on mouse tissues. Both kits give the highest specificity with no background. More…

Untangled neurons promising for cell growth
Brown University via Bioscience Technology
Two wrongs don't make a right, they say, but here's how one tangle can straighten out another. Diane Hoffman-Kim, is an associate professor of medicine in the Department of Molecular Pharmacology, Physiology, and Biotechnology. Every thread of expertise woven through those multidisciplinary titles mattered in the Hoffman-Kim lab's most recent paper, led by graduate student Cristina Lopez-Fagundo. In research published online in Acta Biomaterialia, Hoffman-Kim and Lopez-Fagundo employed their neurophysiological knowledge and technological ingenuity to unravel a tangle of branching, tendrilous nerve cells, or neurons.
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Missed last week's issue? See which articles your colleagues read most.

    Youngest patient ever gets lab-made windpipe (Bioscience Technology)
Dogs detect cancer cells in petri dish (Green Prophet)
Diabetes breakthrough: Newly discovered hormone betatrophin could eliminate insulin injections (International Business Times)
Important microscopic technique advanced for biomedical research (TU Delft via R&D Magazine)
Jackson Lab, Children's Medical Center, Hartford Hospital collaborate on new cancer treatment (Hartford Courant)

Don't be left behind. Click here to see what else you missed.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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