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TOP STORIES

Supreme Court invalidates patents on breast and ovarian cancer genes
ACLU
The U.S. Supreme Court unanimously invalidated patents on two genes associated with hereditary breast and ovarian cancer in response to a lawsuit filed by the American Civil Liberties Union and the Public Patent Foundation on behalf of researchers, genetic counselors, patients, breast cancer and women's health groups, and medical professional associations representing 150,000 geneticists, pathologists, and laboratory professionals.
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Biomarker could predict HPV-related oropharyngeal cancer early on
Genetic Engineering & Biotechnology News
A team led by investigators at the U.S. National Cancer Institute has found that antibodies against human papillomavirus could be useful biomarkers for detecting individuals who are at greatly heightened risk of HPV-related oropharyngeal cancer.
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Big drugmakers think small with nanomedicine deals
Reuters
Is nanomedicine the next big thing? A growing number of top drug companies seem to think so. The ability to encapsulate potent drugs in tiny particles measuring billionths of a meter in diameter is opening up new options for super-accurate drug delivery, increasing precision hits at the site of disease with, hopefully, fewer side effects.
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SPONSORED CONTENT


Magnetic field triggers nanoparticle cancer drug release in controlled manner
Nanowerk News
Scientists at CIC bioGUNE and the Laboratoire de Chimie des Polymères Organiques in Bordeaux have undertaken a project for developing "intelligent" nanoparticles. These polymeric particles act as "nanomissiles" against determined targets and enable the controlled release in space and time of pharmaceutical drugs, releasing their "load" only when and where required. This release of medication is controlled by applying a local magnetic field.
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HIV trial to create new immune systems
Bioscience Technology
People living with HIV will soon be treated with genetically engineered stem cells by the team of Nobel Prize-winning immunologist David Baltimore. The goal: to create, in patients, new immune systems resistant to HIV. "We are very hopeful we can use that as a way of effectively curing patients, and allowing them to live drug-free lives," Baltimore recently told the World Science Festival in New York.
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NSH NEWS


Hawaii Symposium features troubleshooting, IHC/molecular concepts and new GHS training requirements
NSH
The National Society for Histotechnology is happy to announce the first Hawaii Symposium sponsored by both the members of Hawaii & NSH. Join us in beautiful Honolulu, Aug. 18 and 19 for a fantastic program including general sessions and workshops featuring NSH's top rated presenters. This symposium is a great value for your training dollars offering a chance to earn up to 12 continuing education credits! Do you have three or more from your office attending? Contact NSH for discount options — 443-535-4060. Learn more.
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  PRODUCT SHOWCASES
Spring Bioscience - BRAF V600E


Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
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RNAscope: Visualize Single-Copy RNA

RNAscope FFPE Assay Kits make detecting single-copy RNA easy. RNAscope works for virtually any gene in any tissue!

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Slimsette™ Recessed Cover Tissue Cassettes

Available in slotted, biopsy and four compartment versions, the Slimsette™ recessed cover allows for use with lids attached during labeling in cassette printers. Part of the full line of cassettes from LabStorage Systems, Slimsette™ comes in convenient dispenser boxes or preloaded in plastic sleeves for automatic printers. MORE


IN THE NEWS


2 gene variants may predict who will benefit from breast cancer prevention drugs
National Institutes of Health
In women at high risk for breast cancer, a long-term drug treatment can cut the risk of developing the disease in half. Researchers supported by the National Institutes of Health have now identified two gene variants that may predict which women are most likely to benefit from this therapy — and which should avoid it.
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NUS team creates realistic 3-D tumor model
Channel NewsAsia
Researchers from the National University of Singapore's bioengineering and orthopaedic surgery departments have developed a highly realistic three-dimensional tumor model. The model replicates conditions in the body and can be used to track the effectiveness and progress of drug therapy. In a news release, NUS said the model is potentially a more effective method for studying tumors than existing in-vitro and even in-vivo methods.
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Reflectance confocal microscopy enhanced treatment of patients with lentigo maligna
Healio
In vivo reflectance confocal microscopy provided valuable details in supporting optimal diagnoses and management of patients with lentigo maligna, according to study results. Researchers studied 37 patients (mean age, 71 years; 26 women) with lentigo maligna from two tertiary referral melanoma centers in Sydney, Australia.
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  FEATURED COMPANIES
Intelsint Vacuum Tissue Processors
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To find out how to feature your company in the NSH eNewsletter and other advertising opportunities, Contact James DeBois at 469-420-2618.
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Osteoporosis and cancer no more, all thanks to a single drug
iTech Post
According to a study from Duke Cancer Institute, a drug, originally approved to help treat patients suffering from osteoporosis, may also aid in reducing the growth of breast cancer cells, even those cells that have become resistant after application of many therapies. This drug — bazedoxifene — prevents growth of breast cancer cells by lowering down estrogen levels and aiding the production of estrogen receptor that is meant for the destruction of breast cancer cells.
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Cancer researchers find therapeutic potential in 'undruggable' target
Harvard Gazette
Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal and are beginning a creative search for a drug that can block its activity.
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  PRODUCT SHOWCASES
StatClick™ Specimen Transport Vials

We’ve added a click and removed the leak. Turn the lid until it clicks. Ship with confidence that your samples and your reputation will stay perfectly preserved. To learn more, please visit us at: www.statlab.com/statclick or contact us at 800-442-3573.
Hu-on-Hu & Ms-on-Ms Ab Detection


Klear Human
(D103) for Clinical or Pharmaceutical screens of Humanized or Hu-Antibody on human tissues and Klear Mouse (D52) for screening mouse models (transgenic or xenografts) using Ms-Antibody on mouse tissues. Both kits give the highest specificity with no background. More…
Stellaris RNA FISH Probes


Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE
 

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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