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Lab animal diet can foster inaccurate results
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The widespread practice of allowing laboratory rats and mice to eat as much as they want may be affecting the outcome of experiments in which scientists use these "test-tubes-on-four-feet" to test new drugs and other substances for toxicity and other effects. That's the conclusion of a new analysis published in ACS' journal Chemical Research in Toxicology. More

Patient data 'mega-registry' could bolster clinical research
InformationWeek    Share    Share on FacebookTwitterShare on LinkedinE-mail article
If the Office of Management and Budget approves, the Agency for Healthcare Research and Quality will soon establish a "registry of patient registries" to aid researchers doing comparative effectiveness research. The registries referenced in RoPR would include those related to clinical trials and might also encompass patient registries created by healthcare systems and accountable care organizations. More

Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE

HIV treatment results improving — But maybe not as much as thought
TIME    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nearly three-quarters of U.S. HIV patients now receive antiretroviral treatment and are keeping their viral loads in check, according to a large national study. The study shows dramatic improvements in therapy coverage over just the past decade — but not as large a gain as previously estimated, medical researchers say. More

High-quality data from intact tissue sections preserves morphological context
PerkinElmer's multi-modal systems for digital pathology and multi-label microscopy and image analysis let you capture previously undetected features and information by improving your overall quantitation.

Produce publication quality images and benefit from greater sensitivity, improved signal-to-noise ratio as well as reduced background with Abcam’s EXPOSE IHC biotin-free detection systems. MORE

 NSH News

Application & Practice of Hard Tissue histology forum
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Hard Tissue Committee of the National Society for Histotechnology is proud to present a one-day Hard Tissue Forum. Building on the success of the 2010 forum which focused on theory, this all-day event will be an interactive day focused on applications and new technologies. Join us and earn 7.5 contact hours as we seek to further our knowledge and understanding of the histology and analysis of bone, and how this information can better serve in the diagnosis of bone-related diseases and the efficacy and safety of therapeutic treatments. The cost is $139 for members and $159 for nonmembers. Click here for more information.

 In the News

Pathologists, researchers develop technology that predicts cancer relapse
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Over the past decade, clinical laboratory tests that can predict the occurrence or recurrence of breast cancer have opened up a profitable market for the companies that developed these technologies. Now, new research may become the basis of a useful medical laboratory test that could be predictive of prostate cancer relapse. More

Super-resolution microscopy highlights bacterial biofilms
The Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A multi-fluorescent labeling strategy combined with super-resolution light microscopy has allowed researchers to observe the development of a bacterial biofilm in real-time. The team watched the development of the Vibrio cholerae biofilm with "single-protein and single-polymer precision, revealing assembly principles and intermediates." More

Researchers use infant hair to study HIV drug exposure
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Researchers have used hair and blood samples from 3-month-old infants born to HIV-positive mothers to measure the uninfected babies' exposure — both in the womb and from breast-feeding — to antiretroviral medications their mothers were taking. More

Super Sensitive Nickel DAB

GBI Labs’ Nickel DAB kit demonstrates super sensitivity compared to leading companies’ nickel DAB kit. GBI’s Ni-DAB kit produces a sharp black image and perfect color contrast in double or triple staining. Pre-mix can be make 7-hours in advance to use on auto-stainer.
CA IX (MRQ-54) Now Available!
Carbonic Anhydrase IX is expressed in 85-100% of clear cell renal cell carcinomas and is useful in distinguishing clear cell RCC from chromophobe RCC. It is useful in a panel that includes PAX-2, Ksp-cadherin, and CD117. CA IX also can distinguish urothelial carcinoma from collecting duct carcinoma. Learn more here!
Mossberg Labs Launches Special Stains

Mossberg Labs introduces a system approach to Special Staining. A series of complete Special Stains and Rinses that function together as a system. Available as convenient, ready to use kits or as individual components.
When Quality, Consistency, Ease of Use, Economy and Detailed Instruction for Use are important... remember Mossberg Labs for your Special Stain needs.

Protein study brings muscle movement into sharper focus
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Muscle contraction and many other movement processes are controlled by the interplay between myosin and actin filaments. Two further proteins, tropomyosin and troponin, regulate how myosin binds to actin. While theoretical models have in fact described exactly how these muscle proteins interact, this interaction has never previously been observed in detail. More

Modular Micro-Slide & Tissue Shelving System

Lab Storage Systems offers efficient, customizable storage for up to 60 of their popular Micro-Slide and/or Tissue Storage Units. System features an optional, retractable workshelf for easy filing and retrieval. Heavy-duty steel construction allows for up to 675 lbs per shelf. Add-on units available for continuous shelving options.

Blood vessel-forming potential of stem cells from placenta, cord blood
Medical Express    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A study comparing whether endothelial colony-forming cells derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic. More

To test or not to test?
Journal of the American Academy of Physician Assistants    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Ordering tests is a critical part of physician assistant work. Tests help us diagnose and treat patients. We use procedures to further define diseases and ease our patients' symptoms. CT scans aid us in our search for brain tumors and bleeds. Colonoscopies assist us in our fight against cancer. Lab work is perhaps the most common type of test we order. Labs help us find and treat pathology. Lab ordering is quick and easy, especially with the advent of EMR. More

Sensitive and specific 2-plex RNA-ISH assay

Affymetrix’ QuantiGene® ViewRNA Assays enable single-copy RNA sensitivity with exceptional specificity in FFPE tissue sections. From sequence to assay in 1 week. View recent publications.
Medite, Inc.
The Medite® Group is an experienced growing business specializing in high-quality equipment for histology, pathology and cytology labs. MORE

Leukemia mutations linked to aging, not cancer
Science 2.0    Share    Share on FacebookTwitterShare on LinkedinE-mail article
At the time of diagnosis, hundreds of mutations already exist in leukemia cells but new research has found they are a part of normal aging and are not related to cancer. Even in healthy people, stem cells in the blood routinely accumulate new mutations over the course of a person's lifetime. In many cases only two or three additional genetic changes are required to transform a normal blood cell already dotted with mutations into acute myeloid leukemia. More

Nanoscale scaffolds and stem cells show promise in cartilage repair
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Johns Hopkins tissue engineers have used tiny, artificial fiber scaffolds thousands of times smaller than a human hair to help coax stem cells into developing into cartilage, the shock-absorbing lining of elbows and knees that often wears thin from injury or age. While the findings are still years away from use in people, the researchers say the results hold promise for devising new techniques to help the millions who endure joint pain. More

3-D simulation of cold virus could improve drugs
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers are simulating in 3-D, the motion of the complete human rhinovirus, the most frequent cause of the common cold, on Australia's fastest supercomputer, paving the way for new drug development. A new antiviral drug to treat rhinovirus infections is being developed. A team of researchers is now using information on how the new drug works to create a 3-D simulation. More

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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