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Patients share DNA for cures
The Wall Street Journal
Patients with rare and deadly diseases are getting a powerful new boost. Cancer foundations and other nonprofit patient groups are investing tens of millions of dollars to build genetic databases in an effort to speed drug development and jumpstart clinical trials. The databases are designed to collect DNA and other information from patients with hard-to-treat diseases. The material can be analyzed for certain genetic mutations and made available to scholars and pharmaceutical companies.
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New pancreatic stem cell research could transform treatment
Stem cell research is of huge importance because it could lead to dramatic changes in the way we treat certain diseases. These cells, which can differentiate into specialised cells and also divide to produce more stem cells, are already used in a number of medical cases, such as bone marrow transplants and the treatment of leukemia.
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Nanodiamonds improve chemo delivery to brain tumors
Drug Discovery & Development
Researchers at the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles have developed a new drug delivery system using nanodiamonds that allows for direct application of chemotherapy to brain tumors with fewer harmful side effects and better cancer-killing efficiency than existing treatments.
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Looking for similar articles? Search here, keyword BRAIN TUMORS.

New method to combat antibiotic resistant bacteria
Science World Report
There may be a new tool to help combat antibiotic resistant bacteria. Scientists have developed a revolutionary method to identify and characterize antibiotics. The new discovery could help researchers create new antibiotics to treat bacteria. Antibiotic resistant bacteria are a huge issue. In fact, antibiotic-resistant strains of Carbapenem-Resistant Enterobacteriaceae were found to cause infections in patients in nearly 200 hospitals in the U.S. alone this March. These outbreaks are often difficult to contain and can be deadly; nearly one-half of patients die from CRE infections since there are no antibiotics to properly treat them.
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Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
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ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE


FDA panel approves drug to shrink breast-cancer tumors presurgery
CBS News
Doctors are calling the approval of a drug called Perjeta by a Food and Drug Administration advisory panel a historic moment in breast cancer treatment. The panel is approving the medication to shrink tumors before surgery in early-stage patients. The move comes more than a year after Perjeta was approved for late-stage patients. In 40 percent of the cases, it worked so well that surgeons couldn't find the tumor they planned to remove, according to the FDA.
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Microfluidic systems for screening of aptamers
Dr. Afsaneh Motamed-Khorasani
Systematic evolution of ligands by exponential enrichment, or SELEX, is a method to screen the nucleotide ligands from a large library of nucleotide sequences. Aptamers are the nucleotide ligands selected by SELEX method and can be easily and inexpensively produced. Microfluidic devices could provide accurate clinical analysis in less time and could be used for the development of point-of-care devices in the near future.
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Automated RNA-ISH Assays
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Cells reprogrammed in living mice
VideoBriefResearchers have discovered a surprisingly effective way to "reprogram" mature mouse cells into an embryolike state, able to become any of the body's cell types. Their recipe: Let the transformation happen in a living animal instead of a petri dish. The finding could help scientists better understand how reprogramming works and it may one day help breed replacement tissues or organs in the lab — or in patients.
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Virus-derived particles target leukemia
Oncology Nurse Advisor
Unique virus-derived particles have been developed that can kill human blood cancer cells in the laboratory and eradicate the disease in mice with few side effects.
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New organism sheds light on origins of multicellular life
Laboratory Equipment
Researchers have discovered and characterized a new organism that will help scientists understand the molecular mechanisms and ancestral genetic toolkit that enabled animals and fungi to evolve into diverse, multicellular life forms.
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Intelsint Vacuum Tissue Processors
A line of TPs capable to conveniently cover the needs of every Histology lab. Our attention is focused on reliability, flexibility, ease of usage, samples protection and user safety.

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Our singular focus is to optimize histology workflow. Rapid tissue-processing, Automated Embedding, and real-time specimen review are just a few of our many innovations.

A single protein affects susceptibility of cancer cells to chemotherapy
Oncology Nurse Advisor
A newly discovered weakness in cancer cells may make them more susceptible to chemotherapy and other treatments. The HDAC5 protein has been identified as essential for the maintenance of telomeres, which are structures within cancer cells that promote their longevity. Cancer cells with longer telomeres tend to be more resistant to therapies, and those with shorter telomeres tend to be more susceptible. By targeting the mechanism used by cancer cells to maintain telomeres, existing therapies could become far more effective at eradicating cancer than they are today.
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Missed last week's issue? See which articles your colleagues read most.

    New hope for ovarian cancer (By Dorothy L. Tengler)
Research points to promising treatment for macular degeneration (Medical Xpress)
Anthony Pawson, biologist in cell-protein breakthrough, dies at 60 (The New York Times)
Cost effective training at the NSH Symposium/Convention (NSH)
More types of flu shots available this year than ever (USA Today)

Don't be left behind. Click here to see what else you missed.

RNAscope: Visualize Single-Copy RNA

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Colby Horton, Vice President of Publishing, 469.420.2601
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