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Advanced Cell Diagnostics
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Cardinal Health, Inc.
PDS Preclinical Data Systems, Inc.
New technique identifies 1st events in tumor development
Bioscience Technology    Share   Share on FacebookTwitterShare on LinkedinE-mail article
A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events. The technology focuses on chromosomal rearrangements known as translocations. Translocations occur when a broken strand of DNA from one chromosome is erroneously joined with that of another chromosome. Sometimes these irregularities can be beneficial in that they enable the immune system to respond to a vast number of microorganisms and viruses. However, translocations can also result in tumors. More

 NSH News

37th Annual NSH Symposium/Conference C.F.A. Culling Memorial Lecture
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This presentation is intended to engage participants in a manner that promotes cross species and environmental factor considerations as a daily habit. The outcomes of our communities' ability to add value to this collaboration — effectively communicating and implementing improvements — are enormous given the complexity of today's "Wicked Problems." More

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 In the News

High-performance simulation uncovers three classes of protein motion
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Molecular motion in proteins comes in three distinct classes, according to a collaboration by researchers. The research team combined high-performance computer simulation with neutron scattering experiments to understand atomic-level motions that underpin the operations of proteins. More

Antibody-based strategy suggests new therapeutic approach to diabetes, obesity
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The work of a team of scientists at New York's Cold Spring Harbor Laboratory suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes and obesity from being addressed successfully by novel drugs. The target is an enzyme called PTP1B, long known to be an important player in the signaling pathway within cells that regulates the response to insulin. More

CAP/NSH HistoQIP Specialty Series

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Aperio Digital Pathology

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Digital microfluidic platform for multiplexing enzyme assays: Implications for lysosomal storage disease screening in newborns
Clinical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Newborn screening for lysosomal storage diseases has been gaining considerable interest owing to the availability of enzyme replacement therapies. The researchers present a digital microfluidic platform to perform rapid, multiplexed enzymatic analysis of acid α-glucosidase and acid α-galactosidase to screen for Pompe and Fabry disorders. The results were compared with those obtained using standard fluorometric methods. More

Pennsylvania veterinary scientist to receive national medal
The Philadelphia Inquirer    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Ralph Brinster, a prominent veterinary scientist at the University of Pennsylvania, is to receive the National Medal of Science for his work on transgenic lab animals — research that helped lay the foundation for much of modern biomedicine. In the early 1980s, Brinster and colleagues made some of the first mice with foreign genes, a powerful technique for drug development because such mice can be tailored to have a particular disease. More

Total Cutting
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NanoLogix develops rapid, viable microorganism tests that return results in 4 hours
ADVANCE for Medical Laboratory Professionals    Share    Share on FacebookTwitterShare on LinkedinE-mail article
To slow the tide of antibiotic resistance, NanoLogix has developed a series of rapid, viable microorganism tests that return results in about 4 to 6 hours, compared to 24 to 72 hours or more. ADVANCE spoke with NanoLogix CEO, Bret Barnhizer, about the technology. More

Triple Staining Kits

GBI, Labs is a leading company who supplies high quality polymer HRP and AP IHC detection kits for mouse, rabbit, goat, rat, Armenia hamster, sheep, guinea pig and chicken primary antibodies. It is the only supplier who has more than 50 products for IHC double and triple staining for human and mouse (or other animal) tissues. MORE
New Microtome Blades from Sturkey!
C.L. Sturkey proudly introduces, Select microtome blades. Select is an ideal all-purpose blade that cuts any tissue (hard or soft, large or small) with precision to 3 microns. Proudly Made in the USA and backed by our Unconditional Guarantee. Support US manufacturing jobs and call today for free samples!
Slide & Tissue Index Markers

Immediately know when a slide or block has been removed from storage with these LabStorage Systems index markers. Replace it with one of these colorful markers and fill in the information. Index markers stand above slides/cassettes for easy visibility. Six distinctive colors for easy color coding. MORE

Research provides insight into fighting viruses
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers School have determined the structure of a protein that is the first line of defense in fighting viral infections including influenza, hepatitis C, and West Nile. The research is key in the development of broad-based drug therapies to combat viral infections. More

Noninflammatory pseudotumor simulating venous thrombosis after metal-on-metal hip resurfacing
Ortho SuperSite    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This article presents a case of a woman who underwent metal-on-metal resurfacing of the left hip for symptomatic osteoarthritis. Twelve months following implantation, the patient reported painless swelling of the left lower leg. Ultrasound and computed tomography showed a solid cystic lesion in the iliopsoas muscle, which communicated with the hip joint and compressed the external iliac vein. As a consequence, the cystic lesion was resected marginally. More

Scientists say conserved domain of enzyme represents target for autoimmune diseases
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail
Scientists say new insights into how an enzyme involved in T-cell activation binds to the co-receptor CD28 indicate that a conserved domain within the enzyme could represent a potential therapeutic target for autoimmune diseases. An international research team demonstrated that a proline-rich motif in the V3 domain of protein kinase C-θ binds with CD28 and that this interaction is essential for PKC-θ-mediated downstream signaling. More


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ERG Rabbit Monoclonal Antibodies
Epitomics’ Rabbit Monoclonal ERG is your choice for high quality immunohistochemistry. See details and review our full listing of antibodies for anatomical pathology use here. MORE

Survey to measure impact of urologists, GIs creating in-office anatomic pathology labs
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One trend reshaping the profession of anatomic pathology is the growth of in-clinic pathology laboratories by specialist physicians. As each office-based physician group builds its own in-clinic pathology laboratory, local pathology groups and medical laboratories lose access to the tissue specimens these doctors now process in their own pathology lab. A national survey of pathology groups and clinical laboratories is taking place with the goal of identifying the scale and scope of this trend. More

Getting rid of clutter isn't about cleaning up space but rethinking it
ADVANCE for Medical Laboratory Professionals    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Architects and designers create space for people and equipment to work together. Over time technology, clutter and new demands for services and energy efficiency turn once pristine bench tops into cramped work surfaces measured in square inches. If this has happened in your lab, it's time to reclaim your space. More


NanoAndMore USA provides DHMs from Lyncée tec and Resolution Optics. They sense the change in the liquid content of cells and image in 3D.
Milestone was founded in 1988 as a company specializing in advanced microwave instrumentation for analytical and organic chemistry labs. MORE

The many faces of gas chromatography mass spectrometry
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the wake of the recent dioxin poisoning scare in Europe that sparked import bans on some German farm products, GCMS is emerging as the perfect analytical tool for forensic analysis. In fact, its simplicity, sensitivity and effectiveness in separating and identifying components, has made GCMS one of the most important tools in analytical chemistry. More

Transglutaminase 2 facilitates the distant hematogenous metastasis of breast cancer by modulating interleukin-6 in cancer cells
7th Space Interactive    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Inflammation has been implicated in cancer aggressiveness. As transglutaminase 2, which has been associated with inflammatory signaling, has been suggested to play a role in tumor behavior, the researchers propose that TG2 may be an important linker inducing interleukin-6-mediated cancer cell aggressiveness, including distant hematogenous metastasis. More

The Ultimate Histology Tool.
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Paperless Histology Tracking from PDS
Efficient paperless histology tracking for preclinical studies is here! See how the PathData System can bring smart, flexible solutions to your lab. Click PDS eTissueBase.
Stop by and visit us at Booth 210.
Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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