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NSH 39th Annual Symposium/Convention wrapup
The National Society for Histotechnology would like to thank everyone for their participation at this year's Symposium/Convention in Providence, R.I. It was a great success and could not have been done without the amazing volunteers that helped through every step. We would also like to thank all of the support we received from our sponsors and sustaining members. This year we had a great time celebrating 40 years of the society and we can't wait to celebrate the 40th Symposium/Convention next year in the Live Music Capital of the World, Austin! Thank you to the NSH Historian Skip Brown and volunteer David Davis for taking great photos, view the Flickr Collection here. See you next year!
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Shutdown hits patients' hopes for federally funded cancer drug trials
The U.S. government shutdown is dashing the hopes of critically ill Americans like 30-year-old Michelle Langbehn after federally funded clinical trials of potentially life-saving drugs have been closed. The standoff between Republicans and the White House forced most government offices to close recently at the start of the new funding year. Republicans are insisting a government spending bill must carry a measure to rollback President Barack Obama's landmark healthcare reform law enacted in 2010. Obama is adamant that he will not accept that condition.
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Cell-culture transplant possible for neurological disorders
Health Newsline
Finally, there seems to be a ray of hope for the people suffering from Parkinson's and Alzheimer's disease. Experts say that a large number of cells can be successfully grown from the small brain biopsies. These cells can be then put back into the patient's brain by transplantation. This method of transplanting the brain cells grown by the biopsies into the patient's brain can be very helpful for the people who have fallen prey to dreaded medical conditions involving neurological disorders like Alzheimer's and Parkinson's disease.
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Preventing superbugs by deactivating antibiotics with a flash of light
Popular Science
The popularity of antibiotics has led to mutations in bacteria that make the little buggers stronger than ever. But what if we could shut down antibiotics as soon as they're no longer needed?
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Blood pressure drug may enhance cancer treatment
Medical News Today
A new study reveals that a common class of drug used to control high blood pressure could enhance cancer treatment by improving delivery of chemotherapy drugs and oxygen through tumors. A clinical trial is already in progress as a result of the study. Writing about their work in the online journal Nature Communications, researchers from Massachusetts General Hospital, an affiliate of Harvard Medical School, describe how the angiotensin inhibitor losartan increased blood flow and improved chemotherapy drug outcomes in mice with breast and pancreatic cancer.
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Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE
ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
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Mutated stem cells trigger pituitary tumors in children
Medical Xpress
A type of pituitary tumor known as craniopharyngioma appears to form via a different mechanism to that thought to occur in more common tumors, according to a paper in the journal Cell Stem Cell. The novel findings, generated by a team led by the UCL Institute of Child Health, will be further explored to better understand how cell signaling triggers the growth of such tumors — the third most common brain tumor in children — and whether new treatments could be devised to block these signals.
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Drug candidate prevents diabetes in animal model
Drug Discovery & Development
Compugen Ltd. announced that CGEN-15001, an Fc fusion protein drug candidate derived from a novel immune checkpoint protein discovered by Compugen, has been shown to be highly efficient in preventing the development of disease in a well-accepted animal model of autoimmune Type 1 diabetes, known also as juvenile diabetes. The study was performed as part of an ongoing collaboration with Stephen Miller, professor of microbiology-immunology at Northwestern University Feinberg School of Medicine.
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Frustrate with IHC? Rediscover RNA-ISH
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Amniotic stem cells show promise in helping to repair cardiac birth defects
Medical Xpress
Researchers at the University of Michigan Department of Surgery have begun testing an alternative to embryonic stem cells that could one day regenerate muscle tissue for babies with congenital heart defects. A research-in-progress report on this new approach, which uses amniotic stem cells, was presented at the 2013 Clinical Congress of the American College of Surgeons. Although this research is still in an early phase, this new approach has the potential to one day help thousands of babies born each year with congenital heart defects.
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Looking for similar articles? Search here, keyword BIRTH DEFECTS.

Business reviews now available on NSH Histology Marketplace
Nearly seven out of 10 people read online reviews before making a purchase. And in the business-to-business world, reviews are even more important in the decision-making process. To help in your purchasing decisions, we are pleased to announce that we've now incorporated business reviews into our NSH Histology Marketplace. Now you have the opportunity to share your experiences about a company's products or services with your fellow colleagues, or read what others have to say about a potential future vendor. And to help build our database of reviews, we're offering you a chance to win a trip to Hawaii just by writing a review! Visit to search for a company and write a review.
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Intelsint Vacuum Tissue Processors
A line of TPs capable to conveniently cover the needs of every Histology lab. Our attention is focused on reliability, flexibility, ease of usage, samples protection and user safety.

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Sakura Smart Automation
Our singular focus is to optimize histology workflow. Rapid tissue-processing, Automated Embedding, and real-time specimen review are just a few of our many innovations.

Unexpected similarities discovered between nonspecific, specific RNA binding proteins
R&D Magazine
Researchers from Case Western Reserve University School of Medicine have found unexpected similarities between proteins that were thought to be fundamentally different. The team studied how proteins bind to RNA, a process required for gene expression. It is known that some proteins only bind RNAs with certain sequences. Other proteins have been deemed "nonspecific" because they interact with RNAs at seemingly random places. But the Case Western Reserve team has published a study in Nature showing that nonspecific proteins actually do have the ability to be specific about where they bind to RNA — seeking out and binding with particular sequences of nucleotides.
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Missed last week's issue? See which articles your colleagues read most.

    Oncologists call for industry-led global fund to fight cancer (Reuters)
'Jekyll-and-Hyde' protein may be the key to stopping cancer metastasis (Fox News)
Stanford scientists build a microscope to spot the seeds of cancer (Standford Report)
New hope for treating cancer? Patterns seen in 12 types of tumors (Los Angeles Times)
Mexican scientists reveal aflatoxins relationship with cervical and liver cancer in humans (The Medical News)

Don't be left behind. Click here to see what else you missed.

Clot busting simulations test potential stroke treatment
R&D Magazine
Researchers are using computer simulations to investigate how ultrasound and tiny bubbles injected into the bloodstream might break up blood clots, limiting the damage caused by a stroke in its first hours. Strokes are the most common cause of long-term disability in the U.S. and the third most common cause of death. More than 795,000 Americans suffer a stroke every year, which happens when a clot blocks an artery or blood vessel and restricts blood flow to the brain.
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RNAscope: Visualize Single-Copy RNA

RNAscope FFPE Assay Kits make detecting single-copy RNA easy. RNAscope works for virtually any gene in any tissue!

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