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Suspicions about HPV vaccine explored in Preventive Medicine
Science Codex
Suspicions about sexual promiscuity and vaccine safety are explored in an article in the November issue of the journal Preventive Medicine, which dedicates a section of that issue to research concerning the human papillomavirus. "Beliefs, behaviors and HPV vaccine: Correcting the myths and the misinformation" is a review of journal articles and other medical and social science literature exploring beliefs held by the general public that have an impact on HPV vaccination acceptance.
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Nanotech system, cellular heating may improve treatment of ovarian cancer
R&D Magazine
The combination of heat, chemotherapeutic drugs, and an innovative delivery system based on nanotechnology may significantly improve the treatment of ovarian cancer while reducing side effects from toxic drugs, researchers at Oregon State University report in a new study. The findings, so far done only in a laboratory setting, show that this one-two punch of mild hyperthermia and chemotherapy can kill 95 percent of ovarian cancer cells, and scientists say they expect to improve on those results in continued research.
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Putting drug discovery back on target
Medical Xpress
"The world urgently needs new medicines for many diseases such as Alzheimer's, depression, diabetes and obesity," says Professor Chas Bountra. "Yet the pharmaceutical industry's success rate for generating truly novel medicines remains low, despite investing tens of billions of dollars." What's going wrong? Why can't we depend on the vast commercial pharma industry to deliver the new treatments we need?
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FDA sets up rare disease research fund
The US Food and Drug Administration is to support the research of treatment for rare diseases through a new $14 million fund. The money will support 15 research projects that are investigating new ways to tackle rare diseases, defined in the U.S. conditions that affect less than 200,000 people in the country.
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Looking for similar articles? Search here, keyword FDA.

Induced pluripotent stem cells reveal differences between humans and great apes
Science Codex
Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells, a type of cell that has the ability to form any other cell or tissue in the body. Mouse iPSCs were created in 2006 by Kazutoshi Takahashi and Shinya Yamanaka at Kyoto University in Japan, and human iPSCs soon followed — feats which earned Yamanaka the Nobel Prize in Physiology or Medicine last year.
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Stellaris RNA FISH Probes

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ergoCentric Laboratory Seating

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Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
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Targeting mitochondrial ROS: A novel therapy for a number of diseases
By Dr. Afsaneh Motamed-Khorasani
Reactive oxygen species, or ROS, are generated in a number of physiological reactions in our body. They are responsible for a number of diseases, such as cancer, inflammatory, autoimmune and neurodegenerative disorders. Currently, an effective antioxidant therapy is not available. Therefore, an in-depth knowledge of the mechanisms responsible for the production of ROS and their role in the inflammation pathways is critical for the development of new drugs. Recent publications have demonstrated that the ROS derived from mitochondria were responsible for the up-regulation of cytokines through a number of signal transduction pathways.
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Hormones in BRCA gene carriers 'explain cancer risk'
Medical News Today
A new study suggests that abnormal levels of female hormones in the bloodstream may be a reason why women with faulty BRCA1 and BRCA2 genes are more likely to develop breast and ovarian cancer over other cancers. Researchers from the Department of Women's Cancer at University College London in the U.K. say their findings have already led to further research looking at new ways to prevent the cancers in women who are at higher risk.
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New eye treatment effective in laboratory tests
Bioscience Technology
A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, Calif. The studies involved controlling the actions of microRNAs, tiny pieces of RNA that were once considered to be "junk" but are now known to fine-tune gene activation and expression. The researchers showed that treating mice with short RNA strands that precisely target and inhibit microRNAs can stop the aberrant growth of blood vessels.
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Compound derived from vegetables shields rodents from lethal radiation doses
Medical Xpress
Georgetown University Medical Center researchers say a compound derived from cruciferous vegetable such as cabbage, cauliflower, and broccoli protected rats and mice from lethal doses of radiation. Their study, published Oct. 14 in the Proceedings of the National Academy of Sciences suggests the compound, already shown to be safe for humans, may protect normal tissues during radiation therapy for cancer treatment and prevent or mitigate sickness caused by radiation exposure.
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Research: Old cancer drug may help prevent rejection after transplantation
By Joy Burgess
According to new transplant research in Sweden, an old cancer drug, Zebularine, may help to prevent rejection after transplantation. Rejection of the new tissue or organ has long been a problem for patients after receiving a transplant from an organ donor. However, this new discovery may help scientists to develop new anti-rejection treatments that will provide excellent results for transplant patients.
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Missed last week's issue? See which articles your colleagues read most.

    Breaking through cancer's shield (The New York Times)
Only 3 NSH webinars left for 2013 — register today! (NSH)
Doctors search for vaccine to prevent breast cancer (USA Today)
Experiment reveals the ugly side of open-source journal industry (By Pamela Lewis Dolan)

Don't be left behind. Click here to see what else you missed.

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