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Membership renewal and new members are now being accepted
NSH shapes the future of histotechnology through a global community of laboratory professionals committed to continuous learning and high standards of practice. That is our vision. Our vision is 20/20 with you as a part of it. You are part of a community of peers who work together to support the same core values of professionalism, responsibility, respect, integrity and service through collaboration, education and innovation.
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CAP and NSH Uniform Labeling Survey
The College of American Pathologists and the National Society for Histotechnology have partnered to produce guidelines for Uniform Labeling of Slides and Blocks in Surgical Pathology. We invite CAP and NSH members to participate in the open comment period beginning Nov. 8 through Dec. 6 to provide feedback about the draft recommendations. Click here to view complete details.
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With new study, scientists try to drag drug trials into DNA age
At a Nov. 7 meeting in Washington, D.C., researchers from academia, the Food and Drug Administration, the National Cancer Institute, a leading patient advocacy group, and several drug companies are describing a new clinical trial in lung cancer that could fundamentally change the way cancer drugs are studied and approved, speeding medicines that target specific genetic mutations in cancer toward the market and patients.
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Cost-effective method accurately orders DNA sequencing along entire chromosomes
R&D Magazine
A new computational method has been shown to quickly assign, order and orient DNA sequencing information along entire chromosomes. The method may help overcome a major obstacle that has delayed progress in designing rapid, low-cost — but still accurate — ways to assemble genomes from scratch. Data gleaned through this new method can also validate certain types of chromosomal abnormalities in cancer, research findings indicate.
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  Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE

Researchers apply new technique to manipulate virus, make it a possible cancer treatment
Medical Xpress
Purdue University researchers successfully eliminated the native infection preferences of a Sindbis virus engineered to target and kill cancer cells, a milestone in the manipulation of this promising viral vector. "This virus had been known to be a good vector for delivering therapeutic cargo; however it naturally infected all kinds of cells, and these diversions would compete with what we were instructing it to target," said Richard Kuhn, the Gerald and Edna Mann director of Purdue's Bindley Biosciences Center.
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Looking for similar articles? Search here, keyword CANCER TREATMENT.

Oxygen levels in tumors affect response to treatment
Medical Xpress
The genetic make-up of a patient's tumor could be used to personalize his or her treatment and help decide whether he or she would benefit from receiving additional drugs as part of a radiotherapy program, according to a recent study involving scientists from the Manchester Cancer Research Centre.
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Diabetic flies can speed up disease-fighting research
R&D Magazine
In a finding that has the potential to significantly speed up diabetes research, scientists at the University of Maryland have discovered that fruit flies respond to insulin at the cellular level much like humans do, making these common, easily bred insects good subjects for laboratory experiments in new treatments for diabetes.
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ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
Reduce Cost with Same Quality

GBI Labs produces the largest selection of secondary detection kits. We provide free samples to 1st time users. Staining with our kits results in similar or better sensitivity than other detection kits on the market. Some 110mL kits cost as little as $700.00 and 18 ml kit > $300.00.

Stem cells can self-repair some gene damage
U-T San Diego
Artificial embryonic stem cells called induced pluripotent stem cells spontaneously correct certain genetic defects, according to scientists speaking at a discussion recently on new findings in stem cells. During creation of the IPS cells, a few of them manage to repair themselves, said Marina Bershteyn, a researcher in the lab of Arnold Kriegstein of UC San Francisco. These cells grow faster, so with each generation the proportion of these cells increase.
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Understanding integration inhibitors for the treatment of HIV
By Dr. Afsaneh Motamed-Khorasani
Integration of the retroviral genome into the host cell chromatin is the key step in the development of HIV disease. Blocking the integration of viral genome by integrase inhibitors is an attractive therapeutic strategy. Many integrase inhibitors — including peptides, nucleotides, DNA complexes and natural products — were developed by rational drug design strategies. And many of these compounds proceeded for preclinical trials, but further clinical development was halted due to in vivo toxicity and nonspecificity of the drugs towards the target. Better understanding of structure and function of the viral integrase could lead to the development of new integrase inhibitors.
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Business reviews now available on NSH Histology Marketplace
Nearly seven out of 10 people read online reviews before making a purchase. And in the business-to-business world, reviews are even more important in the decision-making process. To help in your purchasing decisions, we are pleased to announce that we've now incorporated business reviews into our NSH Histology Marketplace. Now you have the opportunity to share your experiences about a company's products or services with your fellow colleagues, or read what others have to say about a potential future vendor. And to help build our database of reviews, we're offering you a chance to win a trip to Hawaii just by writing a review! Visit to search for a company and write a review.
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Tamoxifen resistance in breast cancer patients may have mutated gene to blame
The Plain Dealer
Researchers have discovered a mutated version of the estrogen receptor, the presence of which may explain why the drug tamoxifen (brand names: Novaldex and Soltamox) is no longer effective in some patients being treated for ER-positive breast cancer. The findings were published online Nov. 11 in Cancer Research, a journal of the American Association for Cancer Research.
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Missed last week's issue? See which articles your colleagues read most.

    Rare childhood disease may clarify Alzheimer's (Futurity)
Decoding breast cancer drug resistance (The Scientist)
Brain tumor drug IDs cancer cells from healthy ones (Drug Discovery & Development)
Why tumor cells go on dangerous tours (Science Codex)
BRAF status not associated with negative predictors for papillary thyroid cancer (Healio)

Don't be left behind. Click here to see what else you missed.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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