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CAP-NSH uniform labeling of slides and blocks in surgical pathology 1st round of comments
CAP and the NSH convened an expert panel to address the scope question of "What are the essential elements for the proper labeling of paraffin blocks and microscopic slides in the routine practice of surgical pathology?" The first group of comments have been submitted and you can view them by clicking here. The open comment will close Dec. 6 and it is very important that we receive feedback from everyone. For more details and to complete the survey click here.
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2014 Histology Leader Webinars
The National Society for Histotechnology is happy to bring you a new Histology Leaders Webinar Series for 2014. This series is filled with management, education and quality management topics designed for the laboratory supervisor/manager or an educator in a classroom. Choose a topic series or design your own to meet your specific needs. To view all discount packages and schedule of webinars click here.
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Researchers study how excess fat cells interfere with organ function, metabolism
The Wall Street Journal
Why are some obese people healthy, apparently protected from the damaging effects of excess fat on the liver and other organs? Scientists are investigating this question as they look to understand how obesity disrupts normal organ function and causes inflammation, insulin resistance, diabetes and other metabolic abnormalities.
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Merck trial shows more melanoma cancer patients respond to drug
Early data from a small trial of Merck & Co. Inc's experimental immunotherapy cancer drug, known as MK-3475, show that about half of advanced melanoma patients treated with the highest dose of the drug experienced tumor shrinkage. Updated results from the early-stage trial are set to be presented on Nov. 18 at the International Congress of the Society for Melanoma Research in Philadelphia.
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Looking for similar articles? Search here, keyword CANCER TREATMENT.

Scientists create 'mini-kidneys' from human stem cells
Medical News Today
The US National Institute of Diabetes and Digestive Kidney Disease states that more than 20 million adults in the U.S. have some form of chronic kidney disease, showing the need for better knowledge and treatment of the condition. Now, scientists have created miniature 3-D kidney structures from human stem cells with the aim of providing just that.
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  Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE


New research gives clues of antibiotic use and resistance in US children's hospitals
Science Codex
Two studies published in the December issue of Infection Control and Hospital Epidemiology show antibiotic resistance patterns for children have held stable over a seven-year period and surgical patients in U.S. children's hospitals account for 43 percent of all antibiotic use in children's hospitals, presenting an opportunity for targeted intervention.
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What does cancer smell like?
The New York Times
On a lab bench in Philadelphia sits a tiny box lined with nearly invisible nanotubes and gold. A clear plastic pipe runs through it, and a thicket of pins, each sprouting a red or blue wire, protrudes from its end. As air from the pipe wafts over the nanotubes, electrical signals surge out of the box along the wire threads. The whole apparatus is situated near a vial of blood, “sniffing” the air above it through the pipe.
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Steady progress in chemotherapy treatment for biliary tract cancer
By Dr. Afsaneh Motamed-Khorasani
Chemotherapy is widely used for the treatment of advanced biliary tract cancer, or BTC, but the treatment methods are not fully developed in comparison with other types of cancers such as lung and colorectal cancers. Combination therapy, including cytotoxic agents and molecular-targeted agents, has been widely evaluated for advanced BTC for first-line settings. Second-line chemotherapy is found to be more effective for advanced BTC. However, more clinical trials are required to understand the effectiveness of the second-line chemotherapy.
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ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
Reduce Cost with Same Quality

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Study reveals how variant forms of APOE protein impact risk of Alzheimer's disease
Medical Xpress
Carrying a particular version of the gene for apolipoprotein E (APOE) is the major known genetic risk factor for the sporadic, late-onset form of Alzheimer's disease, but exactly how that variant confers increased risk has been controversial among researchers. Now an animal study led by Massachusetts General Hospital investigators shows that even low levels of the Alzheimer's-associated APOE4 protein can increase the number and density of amyloid beta (A-beta) brain plaques, characteristic neuronal damage, and the amount of toxic soluble A-beta within the brain in mouse models of the disease.
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Growing our cures cell by cell in the lab
The Columbus Dispatch
This is the kind of thing that makes Chandan Sen hit a conference room table with excitement: Imagine that a soldier loses a hand in battle and is fitted with a prosthesis, said the director of the Center for Regenerative Medicine and Cell-Based Therapies at Ohio State University's Wexner Medical Center. In some cases, the soldier can use the prosthetic hand to grip a glass. But he can't feel — he can't tell if the glass is hot or cold, or how tightly to hold on. But what if doctors could reprogram some of the soldier's cells to grow nerve cells?
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Bleach helps treat skin damage
San Francisco Chronicle
Bleach — the common household cleaning agent — could be the next big thing in treating skin damage caused by radiation therapy, sun exposure or plain old age, according to new research from Stanford. Researchers, conducting experiments on mice, found that a dilute bleach solution impeded processes that commonly age and damage skin.
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Missed last week's issue? See which articles your colleagues read most.

    Membership renewal and new members are now being accepted (NSH)
Tamoxifen resistance in breast cancer patients may have mutated gene to blame (The Plain Dealer)
CAP and NSH Uniform Labeling Survey (NSH)
With new study, scientists try to drag drug trials into DNA age (Forbes)

Don't be left behind. Click here to see what else you missed.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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