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Researchers: The placebo effect goes beyond humans
University of Florida via Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Rats and humans have at least one thing in common: They both react the same way to a placebo, according to a new University of Florida study. "That was the big finding — that the animals that expected pain relief actually got pain relief when you gave them an inert substance," said co-author John Neubert, a pain specialist and an associate professor with the UF College of Dentistry department of orthodontics. "It helps validate our model that what we do in the rats, we believe, is a good representation of what's being seen in humans." More

Introducing New RabMAbs for Lymphoma
Introducing new rabbit monoclonal antibodies (RabMAbs®) from Epitomics. Epitomics now has over 170 EP Clones, available in 16 Disease Panels including Lymphoma markers to the following antibodies: CD4, CD10, IgD, MUM1. For more information about these antibodies and the advantages of Rabbit Monoclonal antibodies, click here.


Signaling receptor may provide a target for reducing virulence without antibiotics
PhysOrg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For decades, microbiologists thought that bacteria act individually, unaware of their multitudinous counterparts involved in causing the same infection. In the past two decades, however, they have discovered that many species of bacteria "communicate." In fact, bacteria can signal to each other that their numbers are sufficient to launch a coordinated attack. More

Molecular diagnostics testing to remote places down under
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An Australian pathologist is pioneering a new approach for showcasing the role of pathology and demonstrating the dramatic potential of mobile medical laboratories. His technique: take a molecular diagnostics laboratory on the road — in a suitcase. The concept is a portable molecular microbiology lab, consisting of a series of modules. Timothy Inglis, B.M., D.M., Ph.D., Clinical Microbiology Fellow of the Royal College of Pathologists of Australasia and fellow scientist, Adam J. Merritt, are demonstrating high-tech clinical laboratory equipment in a fully mobile laboratory expedition. More

Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE


Strategic agreement between Agfa HealthCare and TRIBVN leads to 1st-of-its-kind pathology imaging solution
DOTmed    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Agfa HealthCare announced it signed a collaboration agreement with TRIBVN for the global distribution of a first-of-its-kind solution integrating digital pathology and radiology images. This strategic agreement brings together two leaders in their respective fields to offer a high-quality solution that will facilitate the exchange of information between clinicians, radiologists and pathologists, resulting in improved communications and a more streamlined workflow. More

Scientists identify calcium 'accelerator' to keep cell power supply going
PhysOrg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team of scientists from Temple University School of Medicine and the University of Pennsylvania has moved another step closer to solving a decades-long mystery of how the all-important flow of calcium into the cell's power source, the mitochondria, is controlled. By painstakingly shutting down the activity of 50 genes, one at a time, they have identified a protein, MCUR1, which hugs the inside of the mitochondrial membrane and is part of an elaborate mitochondrial channel pore system. MCUR1 acts as an accelerator to help regulate calcium coming into the mitochondria from the cell's large reservoir. More



DNA imaged with electron microscope for the 1st time
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It's the most famous corkscrew in history. Now an electron microscope has captured the famous Watson-Crick double helix in all its glory, by imaging threads of DNA resting on a silicon bed of nails. The technique will let researchers see how proteins, RNA and other biomolecules interact with DNA. More


 NSH News


2013 NSH teleconference/webinar series
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
NSH teleconferences (now available as webinars) are a great, inexpensive way to provide continuing education to a large number of employees. The cost for each session is the same regardless of the number of attendees. The one-hour session is usually held the fourth Wednesday of the month, beginning at 1 p.m. EST. Occasionally, due to holidays, it may be the third Wednesday of the month. More


DIGITAL HOLOGRAPHY FOR CELL STUDY

NanoAndMore USA provides DHMs from Lyncée tec and Resolution Optics. They sense the change in the liquid content of cells and image in 3D.
MORE
Sensitive and specific 2-plex RNA-ISH assay

Affymetrix’ QuantiGene® ViewRNA Assays enable single-copy RNA sensitivity with exceptional specificity in FFPE tissue sections. From sequence to assay in 1 week. View recent publications.



 In the News


Researchers uncover the molecular mechanisms leading to basal cell carcinoma initiation
Université libre de Bruxelles via Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One of the most outstanding and unresolved questions in cancer biology is the identification of cells at the origin of cancer and the understanding of the molecular changes that occur in tumor initiating cells from the first oncogenic mutation to the development of invasive cancer. Basal cell carcinoma is the most frequent cancer in humans with more than 1 million new patients diagnosed each year with BCC. Recently, Dr. Cedric Blanpain and his team uncovered the cells at the origin of BCC. More

Common canine virus may lead to new vaccines for deadly human diseases
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the University of Georgia have discovered that a virus commonly found in dogs may serve as the foundation for the next great breakthrough in human vaccine development. Although harmless in humans, parainfluenza virus 5, or PIV5, is thought to contribute to upper respiratory infections in dogs, and it is a common target for canine vaccines designed to prevent kennel cough. In a paper published recently in PLOS ONE, researchers describe how this virus could be used in humans to protect against diseases that have eluded vaccine efforts for decades. More



Researchers explore social media as preventative method for infectious diseases
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When it comes to stopping illness, social media posts and tweets may be just what the doctor ordered. A Kansas State University-led research team is looking at social media as a tool to reduce and prevent diseases from spreading. Researchers are studying whether a well-timed post from a public authority or trustworthy person could be as beneficial as flu shots, hand-washing or sneezing into an elbow. More


New SOX-11 (MRQ-58) for MCL!
SOX-11 expression is specific for the identification of cyclin D1 negative mantle cell lymphoma. SOX-11 is useful due to its high expression in cyclin D1 positive and negative MCL. Many B-cell lymphomas can mimic MCL; therefore, it’s important to have additional antibodies to detect cyclin D1 negative MCL. Learn More.
Slimsette™ Recessed Cover Tissue Cassettes
Available in slotted, biopsy and four compartment versions, the Slimsette™ recessed cover allows for use with lids attached during labeling in cassette printers. Part of the full line of cassettes from LabStorage Systems, Slimsette™ comes in convenient dispenser boxes or preloaded in plastic sleeves for automatic printers. MORE
StatClick™ Specimen Transport Vials
We’ve added a click and removed the leak. Turn the lid until it clicks. Ship with confidence that your samples and your reputation will stay perfectly preserved. To learn more, please visit us at: www.statlab.com/statclick or contact us at 800-442-3573.


Protein 'partner' helps breast cancer spread
Futurity    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The discovery, published online in the Proceedings of the National Academy of Sciences, may also have implications for understanding the metastasis of other forms of cancer and may also light a path to a new treatment strategy. "We've identified a protein that wasn't known before to be involved in breast cancer progression," says Gregg Semenza, professor at the Johns Hopkins University School of Medicine and vascular program director at the university's Institute for Cell Engineering. More

FEI unveils broad correlative microscopy solution set for cell biologists
Globe Newswire via Nasdaq    Share    Share on FacebookTwitterShare on LinkedinE-mail article
FEI announced a suite of solutions for correlative light and electron microscopy. New methods in correlative microscopy from FEI bring data from different imaging techniques together automatically in minutes, giving cell biologists the precise information they need, when they need it. More



FDA approves new flu vaccine by Novartis
HealthAim    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Novartis AG, the Swiss drug maker, won approval on for a flu vaccine that is the first of its kind from the U.S. Food and Drug Administration. The vaccine uses cell cultures from animals and not eggs. The Vaccines and Diagnostics division of the company is headquartered in Cambridge, Mass., and a clinical program and toxicology work were coordinated there with the government of the U.S., said Elizabeth Power a spokeswoman for Novartis. More


Digital Pathology Tools for Biomarker Research
PerkinElmer offers a range of solutions including streamlined TMA & whole slide scanners, patented multispectral imaging and analysis and automated quantitation of biomarkers in tissue. www.perkinelmer.com/tissueimaging
Earn CE with CAP/NSH HistoQIP
Join more than 1,000 laboratories using the CAP’s HistoQIP (HQIP) to make a good laboratory even better. Submit slides to assess your histologists’ technique.


Induced pluripotent stem cell analysis points to mosaic CNV patterns in human skin
GenomeWeb Daily News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Subsets of human skin cells from the same individual can contain slightly different copy number variant profiles in their genomes, according to a new study. As they reported online in Nature, researchers from Yale and Stanford Universities generated multiple iPSC lines per person for seven individuals using skin fibroblast cells as the source of somatic cells for iPSC reprogramming. From genome sequence data on these reprogrammed stem cells, investigators uncovered cell line-specific deletion and duplication patterns, with two validated CNVs occurring per iPSC line, on average. More

Avantik Pre-Filled Formalin Containers

These convenient pre-filled formalin containers are designed with a proprietary patented closure… 100% Leak-proof…guaranteed! 95 kPa compliant. Each container is half filled with 10% neutral buffered formalin. Available in the following sizes: 20, 40, 60, 90, 120mL. Call for your free sample. Volume discounts available.


Massively expanding stem cell suspensions
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Human pluripotent stem cells and their derivatives have gained increased importance for industrial applications in recent years. They have a great potential for therapeutic applications as well. In vitro assays and novel regenerative therapies will require large cell quantities produced under defined conditions. In conventional mammalian cell culture, the utilization of bioreactors is well established, e.g., for the production of recombinant therapeutic proteins, vaccines and antibodies. More


Get your histology CE from MediaLab

Explore our online interactive histology courses, and discover the latest secrets for creating flawless IHC, FISH, special, and routine stains. Complete your annual safety and compliance training hassle free. Document training and get P.A.C.E credits with the included Learning Management System. Get it all with our unlimited annual subscription, available for both individuals and institutions.
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
EndNote X6
EndNote® enables you to move seamlessly through your research process with flexible tools for searching, organizing and sharing your research, creating your bibliography and writing your paper. New in X6: Access your research from anywhere and manage your EndNote library from multiple computers with the new EndNoteSync.
 

Under the Microscope
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