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Stem cells used to produce blood platelets
Reuters    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have for the first time created blood platelet cells by reprogramming stem cells derived from adult cells, offering the potential for a renewable supply of the fragile blood component. Researchers from Japan's Kyoto University presented data at a meeting of the American Society of Hematology showing they were able to create the cells in the laboratory and confirm they had the same life span as normal human platelets when infused in mice. Induced pluripotent stem cells, or iPS cells, are produced by manipulating ordinary human skin or blood cells back to a state in which they are able to differentiate into a number of different cell types. More

Experts: Breast cancer drugs show big promise
The Associated Press via CBS News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Breast cancer experts are tickled pink by two new medicines that could mark the biggest advances in more than a decade. The drugs significantly delay the time until women with very advanced cases get worse. A new study of 808 women showed one drug held cancer at bay for a median of 18 months when given with standard treatment — versus 12 months for others given just the usual treatment. More

 NSH News

2012 NSH Teleconference Series
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
NSH teleconferences are a great, inexpensive way to provide continuing education to a large number of employees. The cost for each teleconference is the same regardless of the number of attendees. Teleconference packets include a set of instructions, handout materials, evaluation form and an attendee sign-in sheet for contact hours. The one-hour teleconference is usually held the fourth Wednesday of the month, beginning at 1 PM EST. More

Gynecologists unfazed as birth control clot concerns resurface
Bloomberg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Undeterred by evidence that newer birth control pills such as Bayer AG's Yasmin may carry more risk of dangerous blood clots, top doctors say they still plan to prescribe them. Yasmin and other contraceptives containing the hormone drospirenone have been the focus of lawsuits and studies that differ in conclusions about the risk. Since the 2001 debut of Yasmin, federal regulators have compiled enough statistics to start raising more questions and have asked advisers to review the science. More

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Teens discover potentially game-changing medical breakthroughs
U.S. News and World Report    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Why leave the scientific breakthroughs to research professors? The teen winner of the 2011 Siemens Competition in Math, Science, and Technology may have created a nanoparticle that could revolutionize cancer treatment. The particle California senior Angela Zhang created can target cancer stem cells, which are notoriously difficult to kill. Zhang, who won a $100,000 college scholarship for her work, tested her method on lab mice and lab-grown cancer cells. More

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Researchers look to immune therapy to treat Alzheimer's
The Globe and Mail    Share    Share on FacebookTwitterShare on LinkedinE-mail article
VideoBriefCanadian scientists are working on an intravenous treatment for Alzheimer's that could halt the progression of the disease and improve cognitive functions. Vancouver researcher Neil Cashman and colleagues have discovered a biomarker on toxic molecules called amyloid-beta oligomers, which are catalysts in the brain degeneration of Alzheimer's. The scientists' industry partner, biopharmaceutical company Cangene Corp., is developing antibodies designed to attack the toxic molecules without harming healthy ones. More

Drug dearth: Worst in oncology, emergency medicine, anesthesia, cardiology
Becker's ASC Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Drug shortages in the United States are felt most strongly in oncology, emergency medicine, anesthesia and cardiology, according to a Cardiology Today report. The number of drug shortages has tripled from 2005-2010, increasing from 61 to 178 in just five years. Drug shortages reached record highs in 2010, and experts say the scarcity has continued in 2011. More

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New Microtome Blades from Sturkey!
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Study unlocks origins of blood stem cells
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A University of Pennsylvania-led research team has discovered a molecular marker for the immediate precursors of hematopoietic stem cells in the developing embryo, which provides much-needed insights for making these cells from engineered precursors. Because HSCs, found in the bone marrow of adult mammals, generate all of the blood cell types of the body, unlocking the secrets of their origin may help researchers to better manipulate embryonic stem cells to generate new blood cells for therapy. More

Breast reconstruction surgery to become safer, more realistic
News-Medical.Net    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Breast reconstruction surgery will become both safer and more realistic thanks to research led by Queensland University of Technology in Australia. The school's Institute of Health and Biomedical Innovation recently conducted a multi-partner research project which used computer-aided design to produce molds modeled on a laser scan of a patient's healthy breast. While these molds have proven to be useful in surgery where tissue is taken from a patient's body, scientists now are developing the technology so that it can allow for breast tissue engineering. More

FDA panel backs Pfizer's kidney cancer drug
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pfizer Inc. won unanimous expert backing for its Inlyta experimental drug for patients with advanced kidney cancer. A Food and Drug Administration advisory committee voted that the drug, also called axitinib, had a favorable benefit-risk profile for such patients after initial treatment has failed. The FDA, which usually approves products that win support from its advisory panels, is due to make a final decision in the first half of 2012. More


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Scar findings could lead to new therapies
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the Stanford University School of Medicine have identified the molecular pathway through which physical force contributes to scarring in mice. Mice genetically engineered to lack an enzyme that is activated by mechanical force demonstrated less inflammation and fibrosis in their incisions than mice in a control group, researchers found. The researchers say they hope their work will pave the way for new treatments of fibrotic diseases as well as inflammatory diseases, such as rheumatoid arthritis. More

Tomosynthesis shines in dense breast cases
Family Practice News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Adding tomosynthesis to full-field digital mammography improved cancer detection and reduced recall rates in women with dense breasts in a study of 293 patients. Dr. Elizabeth Rafferty, of Massachusetts General Hospital, reported on an enriched case set of 69 biopsy-proven cancers, 74 benign biopsies, 50 recalled screening cases, and 100 negative screening cases, all with heterogeneously dense, or extremely dense scores. Calcification was present in 25 percent and non-calcification in 75 percent of cases. More


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FDA drops safety program for potentially risky drugs
Medical Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Food and Drug Administration has stopped applying a safety program for two drugs — Nplate and Promacta — because the program's data was not useful for determining and distinguishing between the effects of the drugs and underlying medical conditions in patients using them. The agency has monitored the safety of Nplate and Promacta since 2008 using the Risk Evaluation and Management Strategy. More

False alarm can spark autoimmune disease
Futurity    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An unchecked signaling mechanism could be the reason the immune system sometimes goes off track to attack the body's own cells. The problem lies in what are called innate immune cells, the first responders to infection, says Cynthia Leifer, assistant professor of microbiology and immunology at Cornell University. The findings may open the door for new therapies for diseases like lupus and arthritis. More

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Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Christine Kraly, Content Editor, 469.420.2685   
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