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Happy holidays from NSH
The National Society for Histotechnology would like to wish everyone a wonderful holiday season. We are thankful for all of your support this year and we look forward to what 2015 brings. Check out our 2014 photo montage, starting from Histotechnology Professionals Day all the way through to our last event in Puerto Rico. Happy Holidays!
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Study shows how breast cancer cells break free to spread in the body
Medical Xpress
More than 90 percent of cancer-related deaths are caused by the spread of cancer cells from their primary tumor site to other areas of the body. A new study has identified how one important gene helps cancer cells break free from the primary tumor. A gene normally involved in the regulation of embryonic development can trigger the transition of cells into more mobile types that can spread without regard for the normal biological controls that restrict metastasis, the new study shows.
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Scientists find genetic wrinkle to block sun-induced skin aging
Medical Xpress
A scientific team at UBC and Providence Health Care have genetically engineered mice with less wrinkled skin, despite repeated exposure to wrinkle-inducing ultraviolet light. The youthful-looking mice were bred without the gene that produces Granzyme B, an enzyme that immune cells use to destroy harmful pathogens. The UBC-Providence team, led by Professor David Granville and postdoctoral fellow Leigh Parkinson, found that Granzyme B also does harm: When produced and released by skin cells in response to UV light, it triggers the breakdown of collagen, a structural protein that makes skin firm.
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Cheap, disposable biometric patch to monitor stress and fatigue in military personnel may be adapted to monitor biomarkers used by clinical pathology labs
Dark Daily
One potential disruptor of medical laboratory testing, as it exists today, are wearable biometric devices. These are already popular with athletes and health-conscious people. To meet this demand, a continual stream of innovative biometric gear is hitting the marketplace. Foremost among the consumers for this technology is the U.S. military. Military leaders recognize the importance of monitoring the physical condition and health of armed forces personnel in the field. Wearable biometric devices are a perfect solution to meet this need.
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Specialist physicians launch patient-centered medical homes, creating opportunities for clinical pathology labs to deliver value-added medical lab testing
Dark Daily
Increasing numbers of medical specialists are launching patient-centered specialty practices. This trend has implications for clinical laboratories and pathology groups because these office-based physicians will want tighter clinical and operational integration with other healthcare providers who treat the same patients. Specialist physicians are watching the growth of patient-centered medical homes and how PCMHs are organized to provide proactive clinical services and maintain access to patients. In adopting this care model for specialty medical practices, these specialists will typically utilize a more extensive menu of medical laboratory tests and anatomic pathology professional support from their laboratory providers.
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Ebola and the year of horrors and heroes
By Joan Spitrey
Time magazine recently announced its Person of the Year: the Ebola fighters. The runners-up included notable people such as Vladimir Putin and the Ferguson protestors. All of those considered where notable newsmakers this year, but nothing captivated the news — especially within healthcare — than Ebola and the brave souls fighting this enormous fight. This past year a small, microscopic virus showed the world its strength. It spotlighted our deficits in disease control and prevention.
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Cancer patients testing drugs on mouse avatars
The Associated Press via Bioscience Technology
Scientists often test drugs in mice. Now some cancer patients are doing the same — with the hope of curing their own disease. They are paying a private lab to breed mice that carry bits of their own tumors so treatments can be tried first on the customized rodents. The idea is to see which drugs might work best on a specific person's specific cancer.
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Molecular link discovered between prostate and breast cancer suggests new treatment approach for men's tumor
Weill Cornell Medical College
Prostate cancer can be driven by the same estrogen receptor responsible for the most common form of breast cancer, Weill Cornell Medical College researchers report. Their findings suggest why the most aggressive forms of prostate cancer do not respond to traditional therapy. The study also opens up potential for new prognostic biomarkers and treatments, researchers say.
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India computes new formula to compensate clinical trial deaths
The Economic Times
India has become the first country in the world to start giving out compensations to victims of clinical trials on the basis of a formula that computes the sum after considering the age and health risk of the deceased. About 21 compensations have been given out by pharmaceutical companies this year to kin of people who were found to have died "due to" clinical trials on experimental drugs since January 2013, an official at the Drug Controller General of India said.
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Automating your lab
Lab Manager
The concept of lab automation sounds almost magical, as if a sophisticated machine here or there makes a lab run by itself. Indeed, automation can improve the efficiency of a lab and more, but figuring out the best "here" or "there" creates the challenge.
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Missed last week's issue? See which articles your colleagues read most.

    What happens when results data from clinical trials goes missing? (The Wall Street Journal)
NSH webinar: Wednesday, Dec.17, 1 p.m. EST (NSH)
Blood, simpler (The New Yorker)
Engineers at Michigan Technological University create pocket-sized, multi-test medical lab-on-a chip using computer-aided design technology (Dark Daily)
Mechanical cues reprogram normal cell lines into stem-like cells (HealthCanal)

Don't be left behind. Click here to see what else you missed.


Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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