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The NSH Convention Committee wants you!
The NSH Convention Committee is now accepting abstracts for the 40th Annual Symposium/Convention taking place Aug. 22-27, 2014 in Austin, and WE WANT YOU! Is there a topic or technique you teach in your lab? Is there someone you know who has a great presentation that needs to be shared? Please submit your idea for this year's National Symposium/Convention. The committee is always looking for first time and returning presenters to complete the program. The finished program will include 90-minute, three-hour and six-hour workshops covering both clinical, veterinary and research histology topics. Need help? Review Presenter Policies here and what exactly you need to submit here.
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New NSH Histology Leader Webinars
The National Society for Histotechnology is happy to bring you a new Histology Leaders Webinar Series for 2014. This series is filled with management, education and quality management topics designed for the laboratory supervisor/manager or an educator in a classroom. Choose a topic series or design your own to meet your specific needs. Your registration fee includes course materials, one login for the webinar and an archived version of the webinar for later reference. Click here for a full schedule of 2014 webinars. Register today!
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Ugly sweaters and holiday cheer
Join other NSH members in the Ugly Christmas Sweater contest. The winner will be announced Dec. 23. Check out what members are posting, or join in the fun and post a photo of yourself in the NSH Facebook Group. Happy holidays everyone!
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New drug, study method show breast cancer promise
R&D Magazine
A novel and faster way to test cancer drugs has yielded its first big result: An experimental medicine that shows promise against a hard-to-treat form of breast cancer. The method involves studying drugs in small groups of people to quickly separate winners from duds.
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ALS toxicity reduced in animal models
Bioscience Technology
Amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, is a devastating illness that gradually robs sufferers of muscle strength and eventually causes a lethal, full-body paralysis. The only drug available to treat the disease extends life spans by a meager three months on average. In a new study published in Nature Genetics, University of Pennsylvania researchers and colleagues have made inroads into the mechanism by which ALS acts. Working with a powerful fruit fly model of the disease, they found a way of reducing disease toxicity that slows the dysfunction of neurons and showing that a parallel mechanism can reduce toxicity in mammalian cells.
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  Stellaris RNA FISH Probes

Stellaris RNA FISH is a new research technology that enables direct detection, localization and quantification of RNA. The low cost per assay, simple protocol, and the ability to localize mRNA and lncRNA to organelles and cellular structures provides obvious benefits for life science research. Custom and catalogued probes sets available. MORE

S'pore scientists: Zebrafish could be key to treating spinal muscular atrophy
Channel NewsAsia
Scientists in Singapore are a step closer to finding a way to treat a spinal disease that currently has no known cure. Spinal muscular atrophy attacks nerve cells, and affects one in every 6,000 births globally — and the clue to the treatment could lie in a small freshwater fish.
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A new gene target for fighting cancer
MIT Technology Review
About half of all cancer patients have a mutation in a gene called p53, which codes for a tumor-suppressing protein that controls cell division. That mutation allows tumors to continue growing even after chemotherapy damages their DNA. A new study from MIT biologists has found that tumor cells with mutated p53 can be made much more vulnerable to chemotherapy by blocking another gene, called MK2. In a study of mice, tumors lacking both p53 and MK2 shrank dramatically when treated with the drug Cisplatin, while tumors with functional MK2 kept growing.
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Cancer and immune cells merge
The Scientist
Macrophages are usually the body's protectors, engulfing pathogens and cleaning up dead cells and debris. But in some cases, cancer cells fuse with these immune cells to possibly become even more harmful, according to a poster presented recently at the American Society for Cell Biology Annual Meeting in New Orleans. The researchers demonstrated that macrophages and mouse colon cancer cells spontaneously fuse when cultured together and noted altered growth in the hybrid cells compared to ordinary cancer cells, prompting speculation that hybridization could spur cancer progression.
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ergoCentric Laboratory Seating

Visit LabStorage System’s updated website to view details about this new laboratory seating with specially formulated Infection Control coating. Non-porous and easily disinfected, this moisture proof coating is anti-bacterial, anti-fungal and stain resistant. more
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
Reduce Cost with Same Quality

GBI Labs produces the largest selection of secondary detection kits. We provide free samples to 1st time users. Staining with our kits results in similar or better sensitivity than other detection kits on the market. Some 110mL kits cost as little as $700.00 and 18 ml kit > $300.00.


Allergies increase risk of blood cancers in women
Oncology Nurse Advisor
A team of scientists looking into the interplay of the immune system and cancer have found a link between having a history of airborne allergies — in particular to plants, grass, and trees — with risk of blood cancers in women. Notably, the study did not find the same association in men, which suggests a possible gender-specific role in chronic stimulation of the immune system that may lead to the development of hematologic cancers.
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Potential malaria vaccine blocks parasite from blood cells
There is new hope for the billions of people exposed to malaria each year. Scientists from Nanyang Technological University in Singapore have discovered a way to block the malaria parasite from invading the blood cells. Using this new research, scientists from NTU are seeking to team up with the vaccine development industry to produce a malaria vaccine. If the process is accelerated by these companies, lead scientist Professor Peter Preiser says the vaccine could be ready in as soon as five years.
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A blood test that predicts suicide?
By Dorothy L. Tengler
Suicide is the 10th-leading cause of death for Americans. In 2010, someone in the United States died by suicide every 13.7 minutes. Alexander Niculescu, a psychiatrist at Indiana University in Indianapolis, has been looking for biological signs of suicide risk in an effort to prevent these tragedies. Because of the brain's complexity and inaccessibility, he has focused on molecular signs, such as biomarkers. Niculescu and colleagues recently identified six such biomarkers in the blood that may identify people at risk of committing suicide.
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'Nanobiopsy' allows scientists to operate on living cells
Imperial College London
Scientists have developed a device that can take a "biopsy" of a living cell, sampling minute volumes of its contents without killing it. Much research on molecular biology is carried out on populations of cells, giving an average result that ignores the fact that every cell is different. Techniques for studying single cells usually destroy them, making it impossible to look at changes over time.
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Missed last week's issue? See which articles your colleagues read most.

    Killing cancer like the common cold (CNN)
New approach may cures wide range of diseases (Fars News Agency)
Renew your NSH membership today (NSH)
New blood test may aid in early detection of breast cancer (Oncology Nurse Advisor)
1 protein, 2 personalities: Study identifies new mechanism of cancer spread (University of Pennsylvania via Medical Xpress)

Don't be left behind. Click here to see what else you missed.

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Senior Content Editor, 469.420.2642   
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