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The great success and enduring dilemma of cervical cancer screening
Cervical cancer, which still kills about 4,000 American women every year, is almost entirely preventable. Proper screening can catch early warning signs that could lead to cancer without the right treatment. But how often women should get screened and which tests should be used has been hotly debated by women, doctors and medical researchers for the past decade. Recently, the American College of Physicians weighed in with guidelines, endorsed by the American College of Obstetricians and Gynecologists, that aim to reduce unnecessary screening.
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SGO palliative care statement in May 2015 Gynecologic Oncology
The May 2015 issue of Gynecologic Oncology features the SGO Statement, “Comprehensive care in gynecologic oncology: The importance of palliative care.” According to the statement: “A collaborative team approach is most effective in addressing the physical, psychosocial, and existential needs of patients, with support beginning for patients at time of initial diagnosis transitioning through effective management of treatment associated-toxicity, and ultimately for some moving to hospice at the end of life.”
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Investigational personalized cellular therapy tolerated well by patients (Phase 1 trial)
Oncology Nurse Advisor
Genetically modified versions of patients' own immune cells successfully traveled to tumors they were designed to attack in an early stage trial for mesothelioma and pancreatic and ovarian cancers. The interim results were presented at the American Association for Cancer Research (AACR) Annual Meeting 2015 in Philadelphia, Pennsylvania. The data adds to a growing body of research showing the promise of chimeric antigen receptor (CAR) T cell technology.
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  ChemoFx Improves Ovarian Cancer Outcomes
ChemoFx® provides invaluable information to physicians choosing from 20+ equivalent treatment recommendations without prior knowledge of how individual patients may respond. ChemoFx determines platinum resistance in primary ovarian cancer and demonstrates longer overall survival by 14 months in recurrent ovarian cancer, making it instrumental in improving patient outcomes.


Raplixa approved to help control surgical bleeding
HealthDay News via The Clinical Advisor
The FDA has approved a spray-dried fibrin sealant (Raplixa) to help control bleeding during surgery, the agency said in a news release. Raplixa's use is sanctioned when standard surgical techniques — such as suture, ligature, or cautery — are "ineffective or impractical," the FDA said. The spray-dried fibrin sealant is dissolved in the blood and triggers a reaction that promotes clotting.
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Factors affecting women's election to undergo bilateral mastectomy identified
Oncology Nurse Advisor
Physicians and cancer survivors are the primary and secondary sources of information, respectively, influencing women to undergo a bilateral mastectomy as their treatment for breast cancer when there is only known cancer in one breast, according to a study presented at the ONS 40th Annual Congress. In this retrospective study, researchers, including oncology nurse navigators and a nurse scientist, surveyed 156 women who elected to have a contralateral prophylactic mastectomy (CPM).
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Uncover Hereditary Cancer Risk for Your Patients
The average OB/GYN has 400 patients who meet criteria for further evaluation of hereditary cancer syndrome. Learn how to identify high-risk patients.


Two congressmen turn up heat on power morcellators
Medscape (Free login required)
Amy Reed, MD, PhD, and her husband, Hooman Noorchashm, MD, PhD, have waged an often lonely campaign to end the use of cancer-dispersing power morcellators in gynecologic procedures and subject all medical devices to tougher safety standards. Lately, however, the couple has gained some influential supporters in the form of two congressmen from their home state of Pennsylvania as well as America's Health Insurance Plans (AHIP), a trade association. The physicians hope that these allies will nudge Congress to hold hearings on medical-device safety.
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Changes in the blood can predict cancer years in advance
CBS News
A simple blood test may be able to predict cancer years before a diagnosis. According to new research from Northwestern Medicine in collaboration with Harvard University, scientists detected a distinct pattern in the changing lengths of telomeres, the protective end caps on our strands of DNA, which may act as a biomarker to predict cancer years before it develops. The study, which is the first to track telomere changes over years in people developing cancer, was published in EBioMedicine.
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A protein 'brake' in metabolic reprogramming that restrains senescent cells from becoming cancerous
Health Canal
In recent years, research has shown that cancerous cells have a different metabolism – essential chemical and nutritional changes needed for supporting the unlimited growth observed in cancer– than normal cells. Now, scientists at The Wistar Institute have identified a way that cells can reprogram their metabolism to overcome a tumor-suppressing mechanism known as senescence, solidifying the notion that altered metabolism is a hallmark of cancer progression. The findings were published online by the journal Cell Reports.
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Women's Cancer News
Colby Horton, Vice President of Publishing, 469.420.2601
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Jessica Taylor, Senior Medical Editor, 202-684-7169  
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