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The American Federation for Medical Research (AFMR) has a rich history with the goal to foster excellence in training and successful development of young investigators. The multi-disciplinary nature of the AFMR allows our members and junior faculty to tap into the professional network of colleagues in other academic medical centers. We also have a well-established platform to promote education as well as mentoring opportunities for medical students, trainees, and junior faculty through our regional and national meetings. AFMR is also a great organization for junior faculty to take on several leadership roles at our regional sections or at the national level. Through these roles, members will have the opportunity to learn leadership skills, planning the meeting/symposium, and interact with colleagues or leaders from several medical specialties.
AFMR publications reflect our organization’s commitment to enhance the training and career development of the AFMR members. The Journal of Investigative Medicine (JIM) is a great platform for our members to disseminate their research work. The Journal of Investigative Medicine High Impact Case Reports (JIM-HICR), an open access journal, is a good forum for trainees to publish their unique and unusual cases.
It is my privilege and honor to serve as the President of the American Federation for Medical Research this year. Please join the AFMR to start your professional journey with us.
Suthat Liangpunsakul, MD, MPH
FASEB BioAdvances, a new peer-reviewed, open access journal, is accepting author submissions as of June 4, 2018. A partnership of the Federation of American Societies for Experimental Biology (FASEB) and John Wiley and Sons Inc., FASEB BioAdvances will be edited by Jasna Markovac, PhD. Dr. Markovac has an academic appointment at California Institute of Technology and will serve as the publication’s Founding Editor, publishing multi/transdisciplinary research from the international community.
On June 11, FASEB submitted comments in response to a Request for Information (RFI) from the National Institutes of Health, United States Department of Agriculture, and the U.S. Food and Drug Administration seeking input on reducing regulatory burden with respect to animal research. The RFI was in response to the 21st Century Cures Act requirement that these agencies “complete a review of applicable regulations and policies for the care and use of laboratory animals and make revisions, as appropriate, to reduce administrative burden on investigators while maintaining the integrity and credibility of research findings and protection of research animals.”
Regarding the article "Guests at ‘hotel influenza’ will help test flu shot" (June 6)(link is external):
The "hotel influenza" study could significantly advance research into the development of a universal flu vaccine and improve the effectiveness of vaccines.
The question is whether Americans recognize the value of vaccines in keeping diseases at bay. More than half of respondents (53 percent) in a survey commissioned by Research!America and the American Society for Microbiology say they did not get the flu vaccine during the last flu season. Among those who said no, 48 percent said they do not trust the flu vaccine, 40 percent said they do not feel they need it to prevent the flu and 26 percent said the flu vaccine is not effective and therefore not worth getting.
On May 17 FASEB submitted comments to the Department of Health and Human Services (HHS) in response to a Notice of Proposed Rulemaking (NPRM) seeking to delay the general compliance date for the revised Federal Policy for the Protection of Human Subjects, i.e., the Common Rule, while allowing implementation of three specific provisions from the revised Rule.
An overwhelming majority of Americans (95%) think infectious and emerging diseases facing other countries will pose a ‘major’ or ‘minor’ threat to the U.S. in the next few years, but more than half (61%) say they are confident the federal government can prevent a major infectious disease outbreak in the U.S., according to a new national public opinion survey(link is external) commissioned by Research!America and the American Society for Microbiology.
Children with allergic diseases have an increased subsequent risk of migraine upon reaching school age
Chang-Ching Wei, Cheng-Li Lin, Te-Chun Shen, An-Chyi Chen
Survival in B-cell primary ocular lymphoma 1997–2014: a population-based study
Deliang L Liu, Zhuojun J Zheng
The impact of low-dose glucocorticoids on disease activity, bone mineral density, fragility fractures, and 10-year probability of fractures in patients with rheumatoid arthritis
Tien-Tsai Cheng, Han-Ming Lai, Shan-Fu Yu, Wen-Chan Chiu, Chung-Yuan Hsu, Jia-Feng Chen, Ying-Chou Chen
Risk of dementia after charcoal-burning suicide attempts: a nationwide cohort study in Taiwan
Shan-Yueh Chang, Wu-Chien Chien, Chi-Hsiang Chung, Hsin-An Chang, Yu-Chen Kao, Hui-Wen Yeh, Yu-Ching Chou, Chung-Kan Peng, Chih-Hao Shen, Nian-Sheng Tzeng
Pilot study on the occurrence of multiple cancers following cancer-related therapy at the University of Florida, Jacksonville (2011–2016)
Karan Seegobin, Estela Staggs, Robina Khawaja, Satish Maharaj, Shiva Gautam, Carmen Smotherman, Fauzia Rana
Recombinant tissue plasminogen activator treatment of pulmonary embolism also improves deep venous thrombosis
Stay informed about JIM and register for e-alerts.
Endoscopic Retrograde Cholangiopancreatography–Induced Splenic Injury in a Patient With Sleeve Gastrectomy
Michael McPhaul, MD,
Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure with significant complications. Splenic hematoma is an extremely rare but known complication following ERCP that has been increasingly reported in the past several years. We report the case of a 44-year-old patient with a history of sleeve gastrectomy who underwent an ERCP that was complicated by both acute pancreatitis and splenic hematoma. She was managed conservatively under close monitoring in the intensive care unit. Clinicians should be aware of this potentially life-threatening complication to make a prompt diagnosis and begin early appropriate management.
An Unusual Cause of Failure to Ventilate
We report an unusual case of endotracheal tube failure. It was due to a manufacturing defect in the internal white plastic piece that is normally depressed by the luer-lock syringe within the blue pilot balloon. Prior to use, the endotracheal tube was tested and functioned normally. A 64-year-old patient in the intensive care unit with a history of hypertension was being mechanically ventilated after uneventful abdominal surgery. After several hours in the intensive care unit, he was noted to be suddenly no longer receiving adequate tidal volumes from the ventilator. It was found that the cuff on the endotracheal tube was not retaining air when it was filled with air from a syringe. This lead to a large “leak” around the endotracheal tube such that the intended tidal volumes set on the ventilator were not delivered to the patient. The patient was uneventfully reintubated and did well. Subsequent investigation revealed the cause to be a manufacturing defect in the internal white plastic piece that is normally depressed by the luer-lock syringe within the blue pilot balloon. Other mechanisms of cuff failure are reviewed in this case report. This case is an unusual reason for cuff failure. Illustrations supplied alert the reader how to identify the appearance of this manufacturing defect in a pilot balloon. This case illustrates the potential device malfunctions that can develop during a procedure, even when the equipment has been tested and previously functioned well. Even small defects developing in well-engineered products can lead to critical patient care emergencies.
A Rare Case of Raoultella planticola Urinary Tract Infection in a Patient With Immunoglobulin A Nephropathy
Raoultella planticola is a gram-negative, aerobic, nonmotile mostly found in environments with high prevalence in soil and water. This organism is a very rare human pathogen as only 29 cases of Raoultella planticola–related infections have been reported until 2017, with only 7 cases in the United States. Only 3 cases of urinary tract infection secondary to R planticola have been reported, 1 in a pediatric patient and 2 in adults. In this article, we present a case of R planticolaurinary tract infection in a 65-year-old male with immunoglobulin A nephropathy. On investigation, the patient was found to be septic and empirical antibiotic was started for gram-negative coverage. The patient showed remarkable improvement and discharged on oral antibiotic for 7 days. R planticola rarely cause infection in humans, with overall good prognosis.
|January 24-26, 2019
||Western Medical Research Conference
|February 21-23 2019
||Southern Regional Meeting
||New Orleans, LA
|March 6-8, 2019
||AFMR Eastern Regional Meeting
|April 4-5, 2019
||Midwestern AFMR Meeting with CSCTR
|April 6-10, 2019
On May 16, 2018, NCATS announced new findings from a collaborative study indicating that an identified compound, named metarrestin, can block the spread of pancreatic and other cancers in various animal models. The team, comprised of researchers from NCATS, the National Cancer Institute and Northwestern University, also observed that mice treated with metarrestin had fewer tumors and lived longer than mice that did not receive treatment. The results are published in Science Translational Medicine.
Millennials already have it tough. Their wages are stagnating, they are unlikely to own homes, and they're often told they are entitled and lazy.
And according to a new report by the Health Foundation think tank, millennials may be the first generation to have poorer health in middle age than their parents.
Medical News Today
Vitamin D is hailed as a wonder nutrient, capable of lowering a person's risk of different forms of cancer. Recent research now confirms that people with high enough levels of this vitamin in their blood have a significantly lower risk of breast cancer.
The controversy surrounding a study of whether moderate drinking might prevent cardiovascular disease isn’t over: If one interpretation of federal regulations is correct, the study may be in violation of Food and Drug Administration requirements meant to protect the health of research volunteers.
STAT has learned that the study’s leaders failed to seek a form of regulatory approval intended to protect study participants and ensure they understand the possible health risks of the research.
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