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ASCLS eNewsBytes
April 14, 2009
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VA Looking Into Possible Contamination at Medical Facilities
from CNN
The Department of Veterans Affairs has launched an investigation into whether there is a connection between improperly sterilized endoscopy equipment and a veteran's positive HIV test. This comes after more than 10,000 veterans were possibly exposed to HIV and hepatitis at three VA facilities while undergoing colonoscopies and other procedures with equipment that had not been properly cleaned. The VA sent letters to those veterans offering free testing for hepatitis B, hepatitis C and HIV. More    E-mail article

Beckman Coulter

Distinguishing Single Cells with Nothing But Light
from Science Daily
Researchers at the University of Rochester have developed a novel optical technique that permits rapid analysis of single human immune cells using only light. Availability of such a technique means that immunologists and other cellular researchers may soon be able to observe the responses of individual cells to various stimuli, rather than relying on aggregate statistical data from large cell populations. Until now scientists have not had a non-invasive way to see how human cells, like T cells or cancer cells, activate individually and evolve over time. More    E-mail article

Doctor Possibly Exposed Hundreds to TB
from ABC News
Barely days old, hundreds of babies in Chicago may already have been exposed to tuberculosis. "We are investigating a situation in which a physician may have unknowingly exposed patients and hospital co-workers," Dr. Terry Mason of the Chicago Public Health Department said. Officials said the 26-year-old resident was on rotation at three different Chicago-area hospitals for the last 10 months, working with at least 150 children and infants at Children's Memorial Hospital; 100 patients, including 17 newborns at Northwestern Memorial Hospital; and an additional 80 babies at Evanston Hospital's Infant Special Care Unit. More    E-mail article

Stem Cells Spur New Eggs in Ovaries of Adult Mice
from Forbes
Researchers in China have demonstrated that female ovaries may be capable of producing new eggs in adulthood and subsequently producing offspring. That runs counter to the long-held belief that female mammals, including humans, are born with a finite number of the eggs or oocytes needed to produce offspring. More    E-mail article

Dried Umbilical Cords in the Retrospective Diagnosis of Congenital Cytomegalovirus Infection as a Cause of Developmental Delays
from Clinical Infectious Diseases
To clarify the impact of congenital cytomegalovirus (CMV) infection on developmental disabilities, 20 children with disabilities of unknown cause were analyzed. Five children were CMV positive and had no clinical manifestations at birth. Intracranial calcification was observed in 4 cases. Thus, congenital CMV infection is a significant cause of developmental disabilities. More    E-mail article

EPA to Recommend Green Claims for Disinfectants and Sanitizers
from Infection Control Today
Officials at the U.S. Environmental Protection Agency have stated they will recommend the adoption of a policy that allows suppliers to make valid claims of "environmental prefer ability" in relation to the marketing of disinfectants and sanitizers. This statement represents a significant departure from the EPA's well-entrenched policy that prohibits "green" claims to be made in conjunction with the promotion of any EPA-registered product, including antimicrobial pesticides. More    E-mail article

Equitech

Assessing Both Genetic Variation and Gene-environment Interactions May Lead to Personalized Gastric Cancer Prevention
from Medscape Today
Technological advances with next-generation DNA-sequencing and microarrays have revolutionized research on the human genome. Three more genomes, including the first one for a cancer patient, have been entirely sequenced and published in Nature. Could this rapid evolution in assessing human genetic variation be incorporated into cancer clinical practice and enable a true overall personalized medicine. Subscription required.    E-mail article

Intravenous Esomeprazole for Prevention of Recurrent Peptic Ulcer Bleeding
from Annals of Internal Medicine
Use of proton-pump inhibitors in the management of peptic ulcer bleeding is controversial because discrepant results have been reported in different ethnic groups. The objective of this clinical study was to determine whether intravenous esomeprazole prevents recurrent peptic ulcer bleeding better than placebo in a multiethnic patient sample. More    E-mail article

Gene Variant Tied to Schizophrenia
from U.S. News & World Report
U.S. researchers say they've spotted a gene variant that may raise the risk of schizophrenia in some people, a finding that may lead to new drug treatments. The study involved a genetic analysis of 24 Canadian families that had multiple members with schizophrenia. A functional DNA change that increases gene expression was found in a gene called NOS1AP, said Dr. Linda Brzustowicz, a professor of genetics at Rutgers University in New Jersey, and colleagues. More    E-mail article

Process by Which Cells 'Hide' Potentially Dangerous DNA Segments Explained
from Science Daily
The DNA in the 23 pairs of chromosomes in each of the billions of cells of the human body is so tightly packed that it would measure six feet in length if stretched end to end. A genome of this size can squeeze into a cell's tiny nucleus because it is compressed into highly condensed chromatin fibers by proteins called histones. More    E-mail article

Food Safety Revamp Urged
from Los Angeles Times
Food safety in the United States is no longer improving, highlighting the need to reevaluate the way an American meal makes its way from farm to table, the U.S. Centers for Disease Control and Prevention said. Rates of salmonella have shown the least improvement of several food-borne illnesses that the agency tracks, according to its annual report. The agency also announced that in response, it would increase capacity at its division overseeing incidents of food poisoning. More    E-mail article




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