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Despite remarkable improvements in short-term outcomes of kidney grafts over the last decade, long-term outcomes have not significantly changed. About one-third of all transplanted patients will lose their graft within 10...

source: Transplantation

Donor-specific antibodies (DSAs) contribute to renal allograft loss. However, biomarkers to guide clinical management of DSA posttransplant or detect humoral alloimmune responses before alloantibodies develop are not available.

source: American Journal of Transplantation

Anti-endothelial cell antibodies (AECAs) have been correlated with increased acute and chronic rejection across all organ types and early graft dysfunction in kidney and heart transplantation. Nevertheless, the lack of appropriate...

source: Human Immunology

Minimizing immunologic complications is critical for long-term patient survival in pediatric solid organ transplant recipients. Multiple factors distinguish pediatric from adult organ transplant recipients which may influence the...

source: Human Immunology

Antibodies against two G-protein coupled receptors (GPCRs), angiotensin II type 1 receptor (AT1R) and endothelin A receptor (ETAR) are among a growing number of autoantibodies that are found to be associated with allograft...

source: Human Immunology

2019 Shipment Schedule For those who may have missed earlier notices, please be aware that the new shipment date for the upcoming 2019 HT-2 survey is Tuesday, September 10th. Because the shipment date has changed, the HT-2 result submission deadline has also changed to Friday,...

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