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NSH NEWS

Registration for the Carolina Symposium is NOW OPEN
NSH
NSH has partnered with the South Carolina Society of Histotechnology and the North Carolina Society for Histotechnology to bring you the second Carolina Symposium! This year the two-day event will take place in the beautiful Greenville, S.C., April 4-5. The symposium offers many great educational opportunities including four general sessions, eight workshops to choose from, an HT readiness course, and an exhibit hall filled with new and improved products/services. This is a great way for you to earn your continuing education credits while enjoying time spent with other histology professionals. For more information regarding registration fees, a full agenda and hotel arrangements, click here. Last year was a great success and we are looking forward to another wonderful experience, click here to view photos from last year's event. See you in Greenville!
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TOP STORIES


Researchers turn adult cells back into stem cells
USA Today
In a step that has implications for stem cell research, human biology and the treatment of disease, researchers in Japan and at Harvard University have managed to turn adult cells back into flexible stem cells without changing their DNA.
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Artificial bone marrow could be used to treat leukemia
Live Science
For decades, doctors have been treating leukemia patients by transplanting stem cells from people with healthy bone marrow. But even though transplants can be a fairly effective treatment, there aren't enough tissue donors to treat every leukemia patient. Now, researchers are taking the first steps toward making bone marrow in a lab: They are growing stem cells in a setting that mimics the natural environment of bone marrow.
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SPONSORED CONTENT


New prostate cancer drugs may not be targeting root cause of disease, scientists warn
Medical Xpress
New drugs being developed for the treatment of prostate cancer may not be targeting the root cause of the disease, according to research published Jan. 24 in Cell Death & Differentiation. Scientists at the University of York have discovered that a process called "methylation," previously thought to drive the development of cancer, occurs in cells that are already cancerous. The findings mean therapies aimed at reversing this process might not be effective against cancer stem cells, allowing the cancer to return.
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Animal model demonstrates role for metabolic enzyme in acute myeloid leukemia
redOrbit.com
In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias. As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia. Now a scientific team at Beth Israel Deaconess Medical Center has generated a transgenic mouse model of the most common IDH2 mutation in human AML, and, in the process, answered a central question of whether these mutant IDH proteins are required for leukemia initiation and maintenance in a living organism.
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PRODUCT SHOWCASE
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NIH scientists map genetic changes that drive tumors in a common pediatric soft-tissue cancer
National Institutes of Health
Scientists have mapped the genetic changes that drive tumors in rhabdomyosarcoma, a pediatric soft-tissue cancer, and found that the disease is characterized by two distinct genotypes. The genetic alterations identified in this malignancy could be useful in developing targeted diagnostic tools and treatments for children with the disease. The study, by researchers at the National Cancer Institute, part of the National Institutes of Health, and their colleagues, appeared in the Jan. 23 issue of the journal Cancer Discovery.
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Researchers open door to new HIV therapy
UC Berkeley
People infected with the Human Immunodeficiency Virus can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos. Researchers at the University of California, Berkeley, and the National Institutes of Health have instead focused on a fourth protein, Nef, that hijacks host proteins and is essential to HIV's lethality.
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Looking for similar articles? Search here, keyword HIV.


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IN THE NEWS


Advanced radiation therapy for head and neck cancers may be better than traditional radiation
Virtual Medical Centre
Patients with head and neck cancer who are treated with an advanced form of radiation therapy may experience fewer side effects and be less likely to die from their disease than patients who receive standard radiation therapy. That is the finding of an analysis published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The study establishes so-called intensity-modulated radiation therapy as both a safe and beneficial treatment for patients with head and neck cancer.
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Study provides clearer picture of cancer risk
Medical Xpress
A University of Vermont researcher has helped to develop a more accurate way of studying genetic changes to identify people at high risk for colon and other cancers. The findings are published in Nature Genetics. Marc Greenblatt, M.D., an associate professor of medicine and oncologist at the University of Vermont and Fletcher Allen Health Care and a faculty member at the Vermont Cancer Center's Familial Cancer Program, co-led a collaborative global effort to interpret genetic data related to hereditary colon cancer. The team's findings will both allow doctors to access publicly available data to more effectively interpret risks and give patients a more accurate picture of familial risk for colon and other cancers.
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Long-living breast stem cells give clues to cancer cells of origin
Medical News Today
Researchers in Australia have found that breast stem cells and their "daughters" have a longer life than previously believed. This newly discovered longer lifespan suggests that these cells could carry damage or genetic defects earlier in life that eventually lead to cancer decades later. The researchers, from Melbourne's Walter and Eliza Hall Institute, have published their results in the journal Nature, and they say their discovery could help with the development of treatments and diagnostics for breast cancer.
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Snapshots of life: Nanotechnology meets cell biology
Nanowerk News
Many of the most exciting frontiers in biomedical research sound like the stuff of science fiction, but here's some work that even looks like it's straight from the set of Star Trek! This scanning electron micrograph captures the pivotal moment when nanospheres — a futuristic approach to drug delivery — are swallowed up by a human fibroblast cell.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Doctors' clothing can spread infectious disease (WNYT-TV)
Fever treatments may cause more flu deaths (LiveScience)
Quality control of mitochondria could be defense against disease (EMBO via Bioscience Technology)
Gene therapy leads to robust improvements in animal model
of fatal muscle disease
(University of Washington)
Brain development: Researchers identify key protein (HealthCanal)

Don't be left behind. Click here to see what else you missed.
 

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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