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New Antibodies from Spring Bioscience

Rabbit monoclonal antibodies engineered for IHC


PD-1 (SP269)
Programmed cell death protein 1 (PD1), also known as CD279, is a member of CD28/CTLA-4 family of T cell regulators. It is expressed on the surface of activated T cells as a negative regulator for immune responses. The binding of PD1 with its ligands PD-L1 and PD-L2 on antigen-presenting cells and tumor cells can trigger inhibition of T-cell function.
SOX-10 (SP267)
SOX-10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX-10 is predominantly found in oligodendrocytes, peripheral glial cells, melanocytes and adult neural crest stem cell populations. SOX-10 is up-regulated in melanoma, glioma, schwannoma, neurofibroma, pheochromocytoma, and lung carcinoid tumor.

For additional product information: email Spring.tech@ventana.roche.com, or call (925) 474-8479
To place an order: email Spring.orders@ventana.roche.com, or call (925) 474-8440

About Spring Bioscience:
Spring Bioscience develops rabbit monoclonal antibodies engineered for use in immunohistochemistry (IHC). Founded by scientists with a primary focus on IHC, Spring has developed a proprietary menu of highly-sensitive Spring Proprietary (“SP”) antibody clones that yield exceptional specificity and consistency in research. Spring Bioscience was acquired by Ventana Medical Systems, Inc., a member of the Roche Group, in 2007 and serves as an antibody center of excellence for Roche with strong pharmaceutical partnerships across the industry.

7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063