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Lab Storage Systems, Inc.
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Exakt Technologies
Method for anti-cancer drug development using tumor explants of surgical specimens
Journal of Visualized Experiments    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Researchers with the department of neurological surgery at Ohio State University Medical Center show how they used freshly-removed surgical specimen of malignant glioma for their experiments. They performed intratumoral injection of TMZ, followed by incubation and analysis on surgical specimens. More



Researchers find gene behind Elephant Man's disfigurement
Medical News Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have identified a gene variant in the rare tissue and bone overgrowth disorder Proteus syndrome that may confirm the cause of the severe disfigurement suffered by the "Elephant Man." Called AKT1, the gene may be a target for future therapies, bringing hope to patients and their families. In this study, the researchers found that a single "point mutation" in the DNA of the AKT1 gene activates the sporadic tissue growth that characterizes Proteus syndrome. A point mutation is the equivalent of spelling one word differently in a large volume of text. More

 NSH News


Journal of Histotechnology: Newest edition now available
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
The National Society for Histotechnology's newest edition of Journal of Histotechnology is now available. Some of the items in this edition include:
  • Immunohistochemical detection of Argonaute 2 in bovine and porcine tissues
  • Gastrointestinal biopsies: more action and less 'chatter'?
  • Loss of samples in the tissue microarray technique: Comparison between slides using adhesive tape and silanized slides
To read these articles and others from this edition, click here.


LSS: New Plastic Cassette Mailer
Lab Storage Systems' new plastic transport container is designed specifically for paraffin blocks. The attached cover snaps securely for transport, yet is easy to open and close. Transparent container allows for easy viewing. 6 block capacity. Fits all standard size tissue & biopsy cassettes. more


Histologist creates jewelry with lab stains
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
Mequita Praet, an NSH member and former board member, has combined histology and jewelry. On her blog, she showcases jewelry that she colors with items such as plasma stain and connective tissue stain. See some of her jewelry featured in her recent blog post. More


Medical Equipment
Source, LLC
- The Ultimate Buying Experience

High quality refurbished histology, pathology, and cytology equipment. Come see where we are going at booths #713 & #715 at the NSH Conference 2011. MORE
ScyTek Laboratories, Inc.
Manufacturer of reagents and kits for the histology laboratory including products for immunohistochemistry, routine & special stains, buffers, fixatives, and mounting media.  MORE




 In the News


Pathology lab concern: Labeling errors
SaferPath    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Hand labeling creates the potential for errors that can occur at a number of touch points in the pathology lab as a patient's tissue biopsy is processed. In some cases, these types of errors are caught and corrected within the pathology lab. In other cases, mislabeling errors can leave the lab unnoticed. For more information and to watch an accessioning process video, visit SaferPath.org.

Popular mammography tool not effective for finding invasive breast cancer
Health News Digest    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Computer-aided detection technology is ineffective in finding breast tumors and appears to increase a woman's risk of being called back needlessly for additional testing following mammography, a large University of California-Davis study has found. The analysis of 1.6 million mammograms in seven states has delivered the most definitive findings to date on whether the popular mammography tool is effective in helping find breast cancer. More



Divided appeals court rules on BRCA case
Association for Molecular Pathology via e Science News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A federal appeals court partially reversed a lower court's ruling in a case challenging patents on two human genes, BRCA1 and BRCA2, associated with hereditary breast and ovarian cancer. The court ruled that companies can obtain patents on the genes but cannot patent methods to compare those gene sequences. The lawsuit charged that the challenged patents are illegal and restrict both scientific research and patients' access to medical care, and that patents on human genes violate the First Amendment and patent law because genes are "products of nature." More

Fluorescent 'spinach' tracks workings of cellular RNA
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have developed a green fluorescent tool that can track the mysterious workings of the various forms of cellular RNA. The investigators report how they developed an RNA mimic of green fluorescent protein — which they dubbed spinach — and describe how it will help unlock the secrets of the complex ways that RNA sustains human life as well as contributes to disease. More



Boston University pathology professor earns innovator award for noninvasive lung cancer test
BU Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Technology that makes possible a new, noninvasive method for the early detection of lung cancer has earned Avrum Spira, an associate professor of medicine, pathology and laboratory medicine at Boston University, the 2011 Innovator of the Year award. "Professor Spira is an entrepreneurial scientist, whose practical approach to science has led to the formation of Allegro Diagnostics, a startup company intent on producing beneficial molecular diagnostics for detecting lung cancer," said Jean Morrison, BU provost and chief academic officer. More


Cut Difficult Tissue with Ease!
Say goodbye to brittle and torn samples with Block Softening and Decalcification products from Polysciences! Try Histoheme, Soft Block and Soft Nail for difficult to cut blocks, and our De-Calcify and Deli-Cal Block Solution to salvage problem blocks right at your cutting station. Ready to use, no mixing required. www.polysciences.com
New Microtome Blades from Sturkey!
C.L. Sturkey proudly introduces, Select microtome blades. Select is an ideal all-purpose blade that cuts any tissue (hard or soft, large or small) with precision to 3 microns. Proudly Made in the USA and backed by our Unconditional Guarantee. Support US manufacturing jobs and call today for free samples!
www.sturkey.com
Superb Histology Products
Anatech Ltd develops and manufactures chemical reagents for the histopathology lab. Our complete line of fixing, processing and staining reagents produce high quality, cost effective histology preparations for diagnostic pathology.


Point/counterpoint: Is Mohs surgery being overutilized?
Skin & Allergy News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Dr. David S. Becker, a Mohs surgeon in private practice in New York, writes that the practice of Mohs micrographic surgery is being overutilized. Becker contends that patients, referring dermatologists, dermatopathologists and Mohs surgeons may play a role. Gary Monheit, Mohs surgeon in private practice in Birmingham, Ala., disagrees. Monheit writes that doctors have recognized that Mohs is the best technique for treatment. More

The EXAKT Cutting/Grinding System
EXAKT Technologies, Inc. began importing the EXAKT Cutting/Grinding System in 1988. Since then the EXAKT System has become the gold standard for the preparation of out-of-the-ordinary samples in many types of industries. And at the NSH in September we’ll be adding something new. Until then visit us at www.exaktusa.com.


Convergence in head and neck cancer
Broad Institute of MIT and Harvard via e Science News    Share    Share on FacebookTwitterShare on LinkedinE-mail
article
In back-to-back papers published in Science, researchers have confirmed genetic abnormalities previously suspected in head and neck cancer, including defects in the tumor suppressor gene known as p53. But the two teams also found mutations in the NOTCH family of genes, suggesting their role as regulators of an important stage in cell development may be impaired. More

Development of one-step SYBR Green real-time RT-PCR
Virology Journal via 7th Space Interactive    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This study aims to develop a quantitative one-step RT-PCR assay to detect bovine viral diarrhea virus type-1 in cell culture. One-step quantitative SYBR Green I RT-PCR was developed by amplifying cDNA template from viral RNA and using in vitro transcribed BVDV RNA to establish a standard curve. This one-step SYBR Green I RT-PCR strategy may be further optimized as a reliable assay for diagnosing and monitoring BVDV infection in animals. It may also be applied to evaluate candidate agents against HCV using BVDV cell culture model. More


Open the door to personalized purchasing!

Your Leica Direct online shop is now open! Created specifically for you, Leica Direct is a total solution for purchasing all your histology consumables and general laboratory supplies.
MORE
Epitomics -
the Rabbit Monoclonal Leader

Epitomics, Inc.: the primary source for rabbit monoclonal antibodies (RabMAb®). Find out how our EP Clones and IHC kits meet your anatomical pathology needs. MORE


Dense breasts hike risk of aggressive cancer
MedPage Today (free registration required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Increasing breast density conferred a progressively greater risk of breast cancer with aggressive characteristics in postmenopausal women, according to a study. Women with at least 50 percent breast density on mammographic study had triple the risk of breast cancer compared with women who had less than 10 percent density. Density did not influence tumor histology, lymph node involvement, HER2 status or progesterone receptor status, investigators reported. More



Quantitative analysis of images by visual walk-in of simulations
Science 2.0    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Many imaging techniques like microscopy only allow lab technicians to see the flat projection of what is actually three dimensional. It can be impossible to derive crucial information about relative locations. According to Sascha Vongehr at the University of Nanjing, a novel computer program and its user essentially collaborate to create what Vongehr calls a visual walk-in of simulations. More

Waived testing: A prescription for safety
ADVANCE for Medical Laboratory Professionals    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Clinical Laboratory Improvement Amendments remains the most sweeping federal law affecting the laboratory industry. Its purpose is to safeguard the "accuracy, reliability and timeliness" of patient test results. To accomplish that objective, CLIA broadened the regulatory reach of existing law to include all U.S. facilities, including physician operated laboratories, not previously subject to CMS oversight. More
 
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