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 Top Stories

Scientists build 'mechanically active' DNA material
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for UC Santa Barbara scientists Omar Saleh and Deborah Fygenson, the reality of it is not that far away. By blending their areas of expertise, the pair have created a dynamic gel made of DNA that mechanically responds to stimuli in much the same way that cells do. The results of their research were published online in the Proceedings of the National Academy of Sciences. More

Rabbit Monoclonals for Lymphoma, Prostate
Epitomics has over 150 EP Clones, available in 16 Disease Panels including Lymphoma, and Prostate markers. New antibodies for anatomic pathology include: Aldh1A1, CD30, LIN28, Myogenin PAX5, and S100P. Of particular interest is novel antibody, PAX5 and S100P, distinguished by its high quality FFPE staining. Find out more here.


More clinical pathology laboratories use middleware for business intelligence and lab-specific customer relationship management
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Within the clinical laboratory industry, there's an interesting conjunction of two fast-moving trends. One trend is the growing use of middleware by medical laboratories of all sizes. The second trend is the goal of converting any type of manual work process in the lab into an automated work process. These trends often intersect when clinical laboratories and pathology groups use middleware to automate manual processes. More

Placebo effect linked to dopamine-clearing enzyme
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Patients who carry one particular functional polymorphism of an enzyme responsible for clearing dopamine from the prefrontal cortex region of the brain are more likely to respond to placebo therapy than those with a different variant of the enzyme, as long as the placebo is administered in a caring, positive manner, researchers report. The polymorphism generates a less-active version of the enzyme catechol-O-methyltransferase, which is less efficient than the native enzyme at mopping up dopamine that has been released from nerve synapses. More

Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE


New blood-vessel-generating cell with therapeutic potential discovered
redOrbit    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the University of Helsinki, Finland, believe they have discovered stem cells that play a decisive role in new blood vessel growth. If researchers learn to isolate and efficiently produce these stem cells found in blood vessel walls, the cells offer new opportunities in the treatment of cardiovascular diseases, cancer and many other diseases. The study will be published in the PLOS Biology journal. More


 NSH News


NSH opens abstract submissions for the 2013 Symposium/Convention
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The purpose of the National Society for Histotechnology Symposium/Convention is to provide an interchange of ideas pertinent to histotechnology and to advance professional growth, standards, knowledge and performance in histotechnology through continuing and formal educational programs. The NSH Convention Committee is now accepting abstracts for the 39th Annual Symposium/Convention taking place Sept. 20-25 in Providence, R.I. The finished program will include 90-minute, three- and six-hour workshops covering both clinical, veterinary and research histology topics.

NSH partially funds the participation of presenters. Presenters flying domestically or from Canada receive round trip airfare, two nights in a convention hotel and two days per diem. NSH does not pay honorariums.

Click here for complete details and to submit an abstract for consideration.
Click here to get an idea of sessions taught last year.

Important dates:
Oct. 18: Online abstract submissions open
Jan. 4: Online abstract submission deadline
Feb. 22: Abstract acceptance/rejection notification emails sent
March 7: Revised abstracts due
April 1: Final program announced





 In the News


Putting the genome to work in breast cancer
OncLive    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Although breast cancer is among the best-characterized tumor types, continuing efforts to refine the sequencing of the human genome are opening the door to a new treatment paradigm in which oncologists will have swift access to a wealth of information that will enable more personalized therapy for patients at earlier stages of disease. More

Immune cells make flexible choices
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats is to randomly combine DNA segments for the production of receptors on lymphocytes — a type of white blood cell. The number of possible receptors that can be produced in this way is about 1000 times the number of stars in our galaxy — one followed by 15 zeroes. New research at the Weizmann Institute can help explain how the immune system maintains its complexity while giving preference to certain receptors. More


DIGITAL HOLOGRAPHY FOR CELL STUDY

NanoAndMore USA provides DHMs from Lyncée tec and Resolution Optics. They sense the change in the liquid content of cells and image in 3D.
MORE
Sensitive and specific 2-plex RNA-ISH assay

Affymetrix’ QuantiGene® ViewRNA Assays enable single-copy RNA sensitivity with exceptional specificity in FFPE tissue sections. From sequence to assay in 1 week. View recent publications.


World's most advanced mirror for giant telescope completed
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at the University of Arizona and in California have completed the most challenging large astronomical mirror ever made. For the past several years, a group of optical scientists and engineers working at the UA Steward Observatory Mirror Laboratory underneath the UA's football stadium have been polishing a 27.5-foot diameter mirror with an unusual, highly asymmetric shape. By the standards used by optical scientists, the "degree of difficulty" for this mirror is 10 times that of any previous large telescope mirror. More



10 tips for successful in vivo optical imaging
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In vivo optical imaging is a powerful methodology allowing users to monitor molecular and functional events noninvasively in a broad array of applications from cancer biology to microbiology using either bioluminescent or fluorescent reporters. The ultimate success and reproducibility of your imaging experiments can be greatly enhanced by following these simple tips. More


New SOX-11 (MRQ-58) for MCL!
SOX-11 expression is specific for the identification of cyclin D1 negative mantle cell lymphoma. SOX-11 is useful due to its high expression in cyclin D1 positive and negative MCL. Many B-cell lymphomas can mimic MCL; therefore, it’s important to have additional antibodies to detect cyclin D1 negative MCL. Learn More.
DispoCut™ Disposable Dissecting Boards

Lab Storage Systems is proud to offer the DispoCut™ disposable dissecting board. This dissecting board is strong enough to reuse, yet inexpensive enough to throw away. Conveniently printed on both sides in inches and metric measurements. Available in 3 sizes. MORE
StatClick™ Specimen Transport Vials
We’ve added a click and removed the leak. Turn the lid until it clicks. Ship with confidence that your samples and your reputation will stay perfectly preserved. To learn more, please visit us at: www.statlab.com/statclick or contact us at 800-442-3573.


Research sheds light on important role of autophagy, or self-eating cells, in developing new anti-inflammatory therapies
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Research just carried out in the Immunology Research Center, led by Dr. James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy regulates the production of inflammatory molecules and may therefore represent an effective target for the development of new anti-inflammatory therapeutics. The findings have been recently published online in the Journal of Immunology. More



Scientists: 1st milk of vaccinated cows protects against HIV
Sci-News.com    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The team, led by Dr. Marit Kramski of the University of Melbourne's Department of Microbiology and Immunology, vaccinated pregnant cows with an HIV protein and studied the first milk that cows produced after giving birth. The first milk, called the bovine colostrum, is naturally packed with antibodies to protect the newborn calf from infections. The vaccinated cows produced milk that contains antibodies that defend against HIV. More


Digital Pathology Tools for Biomarker Research
PerkinElmer offers a range of solutions including streamlined TMA & whole slide scanners, patented multispectral imaging and analysis and automated quantitation of biomarkers in tissue. www.perkinelmer.com/tissueimaging
CAP's Histology Competency Assessment
Learn more about the histology competency assessments through the CAP’s Competency Assessment Program. Also see the self-paced, interactive histology Pro Courses. All courses offer CE.


Tips from the journals of the American Society for Microbiology
Science Codex    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Patients newly diagnosed with pediatric Crohn's disease had significantly different levels of certain types of bacteria in their intestinal tracts than age-matched controls, according to a paper in the October Journal of Clinical Microbiology. The work may ultimately lead to treatment involving manipulation of the intestinal bacteria. More

Stem cell bodyguards
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood-forming stem cells can proliferate and differentiate into billions of mature blood immune cells to help the body cope with infection, for example, or extra red blood cells for low oxygen levels at high altitudes. Even in emergencies, however, the body keeps to a long-term plan: It maintains a reserve of undifferentiated stem cells for future needs and crises. More


Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
Get your histology CE from MediaLab

Explore our online interactive histology courses, and discover the latest secrets for creating flawless IHC, FISH, special, and routine stains. Complete your annual safety and compliance training hassle free. Document training and get P.A.C.E credits with the included Learning Management System. Get it all with our unlimited annual subscription, available for both individuals and institutions.
Avantik Pre-Filled Formalin Containers
These convenient pre-filled formalin containers are designed with a proprietary patented closure… 100% Leak-proof…guaranteed! 95 kPa compliant. Each container is half filled with 10% neutral buffered formalin. Available in the following sizes: 20, 40, 60, 90, 120mL. Call for your free sample. Volume discounts available.
 

Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Ashley Whipple, Content Editor, 469.420.2642   
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