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 Top Stories

Owners of regional independent clinical pathology laboratory companies make plans to visit senators and representatives
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Recently, an intrepid group of clinical laboratory owners gathered in the nation's capital specifically to visit their senators and representatives. The goal was to educate these elected officials about the tenuous financial condition of independent medical laboratory companies. In particular, ongoing budget cuts to the Medicare Part B Clinical Laboratory Test Fee Schedule are undermining the ability of medical laboratories to deliver top-flight lab test services. More

Introducing New RabMAbs for Lymphoma
Introducing new rabbit monoclonal antibodies (RabMAbs®) from Epitomics. Epitomics now has over 170 EP Clones, available in 16 Disease Panels including Lymphoma markers to the following antibodies: CD4, CD10, IgD, MUM1. For more information about these antibodies and the advantages of Rabbit Monoclonal antibodies, click here.


Cancer resistance in blind mole rats may hold key to prevention in humans
Asbestos.com    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The blind mole rat may be unsightly, but this subterranean rodent has an extraordinary characteristic — it seems to be impervious to cancer. Biologists at the University of Rochester recently uncovered why, and the finding may lead to better treatments and prevention techniques for human cancer patients. More

Animal testing may be overtaken by 'organ-on-a-chip'
Medical News Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A U.S. study that successfully used a "lung-on-a-chip" to mimic a chemotherapy drug side effect brings closer the day when drug developers use "organ-on-a-chip" methods to replace more traditional approaches like animal testing and cell cultures, which are costly and time consuming. More

Human on Human Detection Kits

GBI Labs’s Klear Human Polymer Detection kits can detect human primary antibody on human tissue with no background. It is a biotin-free system. Special blocking buffer and human antibody enhancer are used to provide excellent sensitivity and high specificity. MORE


Researchers remove extra chromosome from Down's syndrome cells — Could a gene therapy be next?
io9    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists from the University of Washington have successfully removed an extra copy of chromosome 21 in cell cultures belonging to a person with Down's syndrome. While the breakthrough is unlikely to result in an outright treatment for the condition, it could pave the way for gene therapies in which many of the health conditions associated with the chromosomal disorder can be significantly alleviated. More


 In the News


Targeting protein could prevent metastasis of cancer cells
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at King's College London have uncovered a protein required by cancer cells to spread to other parts of the body, highlighting it as a potential target for future treatments to prevent secondary cancers. More



NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model
The Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a mouse model of multiple sclerosis, researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin — the insulating material that encases nerve fibers and facilitates electrical communication between brain cells. More


DIGITAL HOLOGRAPHY FOR CELL STUDY

NanoAndMore USA provides DHMs from Lyncée tec and Resolution Optics. They sense the change in the liquid content of cells and image in 3D.
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Sensitive and specific 2-plex RNA-ISH assay

Affymetrix’ QuantiGene® ViewRNA Assays enable single-copy RNA sensitivity with exceptional specificity in FFPE tissue sections. From sequence to assay in 1 week. View recent publications.


3-D printed biorobot will enter your gut to track and destroy toxins
ExtremeTech    Share    Share on FacebookTwitterShare on LinkedinE-mail article
VideoBriefWhen researchers boast rather casually that making new variations of their invention is as simple as editing a CAD file, we might assume they are talking about a new sort of coffee mug, or perhaps a revolutionary spool for garden hose. Certainly such a simple and cost-effective design process could never give rise to something as complex as a biorobot, a chimera of industrial gel and living tissue designed work inside the human body. However, after researchers at the University of Illinois set themselves the task of creating just such a robot, that's precisely what they did. More



Origin matters for brain tumors
redOrbit    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Brain tumors arising from different cell types might require different — and more personalized — treatment approaches. Cancers arise when a normal cell acquires a mutation in a gene that regulates cellular growth or survival. But the particular cell this mutation happens in — the cell of origin — can have an enormous impact on the behavior of the tumor and on the strategies used to treat it. Dr. Robert Wechsler-Reya, professor and director of the Tumor Development Program in Sanford-Burnham's NCI-designated Cancer Center, and his team study medulloblastoma, the most common malignant brain cancer in children. A few years ago, they made an important discovery. More


New SOX-11 (MRQ-58) for MCL!
SOX-11 expression is specific for the identification of cyclin D1 negative mantle cell lymphoma. SOX-11 is useful due to its high expression in cyclin D1 positive and negative MCL. Many B-cell lymphomas can mimic MCL; therefore, it’s important to have additional antibodies to detect cyclin D1 negative MCL. Learn More.
Slimsette™ Recessed Cover Tissue Cassettes
Available in slotted, biopsy and four compartment versions, the Slimsette™ recessed cover allows for use with lids attached during labeling in cassette printers. Part of the full line of cassettes from LabStorage Systems, Slimsette™ comes in convenient dispenser boxes or preloaded in plastic sleeves for automatic printers. MORE
StatClick™ Specimen Transport Vials
We’ve added a click and removed the leak. Turn the lid until it clicks. Ship with confidence that your samples and your reputation will stay perfectly preserved. To learn more, please visit us at: www.statlab.com/statclick or contact us at 800-442-3573.


Diabetes targeted by new 'hormone hybrids'
WebProNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team of scientists may have achieved a major milestone in the treatment of diabetes and obesity. The researchers engineered a method to deliver hormones to specific tissues in the body, while keeping them away from others. The team, led by Dr. Matthias Tschöp, from the Technical University of Munich and the Helmholtz Center, and Richard DiMarchi, a chemist at Indiana University, was able to engineer natural gut peptides to carry small steroids known to act at the cell nucleus. Their hope was to deliver the steroid only inside cells. More



Human umbilical cord blood cell co-culture supports embryonic stem cell expansion
PhysOrg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers in Taiwan have developed a "safe, feasible and robust co-culture system" supplied by human umbilical cord mensenchymal stem cells to feed the sustained culture used for human embryonic stem cell expansion prior to cell transplantation. The co-culture, said the researchers, "appears to eliminate the most feared characteristic of transplanted hESCs," which is their propensity to form tumors. More


Digital Pathology Tools for Biomarker Research
PerkinElmer offers a range of solutions including streamlined TMA & whole slide scanners, patented multispectral imaging and analysis and automated quantitation of biomarkers in tissue. www.perkinelmer.com/tissueimaging
Earn CE with CAP/NSH HistoQIP
Join more than 1,000 laboratories using the CAP’s HistoQIP (HQIP) to make a good laboratory even better. Submit slides to assess your histologists’ technique.


Skin cell reveal DNA's genetic mosaic
R&D Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening, according to Yale University School of Medicine researchers. Published online in Nature, the study paves the way for assessing the extent of gene variation and for better understanding human development and disease. More

Avantik Pre-Filled Formalin Containers

These convenient pre-filled formalin containers are designed with a proprietary patented closure… 100% Leak-proof…guaranteed! 95 kPa compliant. Each container is half filled with 10% neutral buffered formalin. Available in the following sizes: 20, 40, 60, 90, 120mL. Call for your free sample. Volume discounts available.


Study: Body may be able to 'coach' transplanted stem cells to differentiate appropriately
HealthCanal.com    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pluripotent stem cells are nature's double-edged sword. Because they can develop into a dizzying variety of cell types and tissues, they are a potentially invaluable therapeutic resource. However, that same developmental flexibility can lead to dangerous tumors called teratomas if the stem cells begin to differentiate out of control in the body. More


Get your histology CE from MediaLab

Explore our online interactive histology courses, and discover the latest secrets for creating flawless IHC, FISH, special, and routine stains. Complete your annual safety and compliance training hassle free. Document training and get P.A.C.E credits with the included Learning Management System. Get it all with our unlimited annual subscription, available for both individuals and institutions.
Spring Bioscience - BRAF V600E

Spring Bioscience is leading the research industry by pioneering novel, next generation antibodies that can differentiate mutant and normal protein, enabling pathologists to see relevant mutations within their cellular context. Having already released Exon19 and EGFR L858R for exclusive use by Ventana Medical Systems, Spring Bioscience has launched BRAF V600E.
Click here to find out more.
EndNote X6
EndNote® enables you to move seamlessly through your research process with flexible tools for searching, organizing and sharing your research, creating your bibliography and writing your paper. New in X6: Access your research from anywhere and manage your EndNote library from multiple computers with the new EndNoteSync.
 

Under the Microscope
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