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PDS Preclinical Data Systems, Inc.
Scientists develop vaccine that successfully attacks breast cancer
Bioscience Technology    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at Mayo Clinic in Arizona and the University of Georgia have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases — including those that are resistant to common treatments. The vaccine, described in the journal Proceedings of the National Academy of Sciences, reveals a promising new strategy for treating cancers that share the same distinct carbohydrate signature, including ovarian and colorectal cancers. More



Most NBA players recover from meniscus tears
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A handful of players are sidelined by torn knee cartilage every season in the National Basketball Association, according to a new study, and most make a full recovery within a couple months. At least three NBA teams recently announced that one of their players would miss the first few weeks of a shortened season with a torn meniscus. The new study suggests that when those athletes do make it back on to the court, they'll be able to play at the same level as before they got injured. More

Study: Naked mole-rats reveal clues to treating arthritis
CNN    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Experiments on naked mole-rats may lead to better treatments with fewer side effects for humans suffering from painful inflammatory arthritis, according to a new study published in the journal Science. The partially blind, hairless, wrinkly, cold-blooded mammals were good candidates for the study because of their unique insensitivity to acid-induced pain. More


 NSH News


Troubleshooting stains 1-day forum
NSH    Share    Share on FacebookTwitterShare on LinkedinE-mail article
NSH has recruited two if its highest-rated speakers to bring you this one-day forum where attendees will learn good practices for both H&E and IHC staining. The morning provides an opportunity for you to learn if your "gold standard" H&E is living up to expectations. Then spend your afternoon learning how to optimize IHC regardless of the fixative, antibody or protocol used. More

Gene therapy helps hemophilia patients
Drug Discovery & Development    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An experimental gene therapy technique boosted the production of a vital blood clotting factor in six people with hemophilia B, according to new research supported by the National Institutes of Health. The therapy could give patients a long-term solution for preventing prolonged bleeding episodes and spontaneous bleeding. More

RNAscope: Visualize Single-Copy RNA
RNAscope FFPE Assay Kits make detecting single-copy RNA easy. RNAscope works for virtually any gene in any tissue!

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First-of-its-kind surgery helps cancer patient keep her voice
University of Michigan    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When Sherry Wittenberg was diagnosed with a rare cancer in the cricoid cartilage of her larynx, doctors told her the only way to treat the condition was to remove her voice box. Wittenberg sought a second opinion at the University of Michigan Health System, where she was offered a new procedure that, if successful, would allow her to keep her voice. The technique reconstructs a ring of cartilage in a patient's neck called the cricoid with a slice from the tip of one shoulder blade. More

Researchers find cartilage-stabilizing protein also drives cartilage growth
Health Canal    Share    Share on FacebookTwitterShare on LinkedinE-mail article
University of California-Davis researchers have discovered that the protein responsible for the structural integrity of cartilage has a major role in creating it as well. The protein, cartilage oligomeric matrix protein, binds to growth-promoting molecules and links them with the cellular framework that forms cartilage. The investigators also discovered that COMP increases the production of growth factors called transforming growth factor-beta, creating a supportive environment for the development of new cartilage. More


CAP/NSH HistoQIP Biopsy Series
Use the CAP's HistoQIP Biopsy Series (HQIPBX) to assess the preparation of H&E stained slides in your laboratory. MORE
Aperio Digital Pathology

Aperio’s outstanding digital slide scanners, data management and image analysis software, and digital pathology services lowers costs, increases efficiency, and manages workflow in pathology labs.
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Without autopsies, hospitals bury their mistakes
ProPublica    Share    Share on FacebookTwitterShare on LinkedinE-mail article
VideoBriefAutopsies once were an integral part of American healthcare, performed on roughly half of all patients who died in hospitals. Today, data from the Centers for Disease Control and Prevention show, they are conducted on about 5 percent of such patients. Hospitals are not required to offer or perform autopsies. Some facilities and doctors shy away from them, fearing they may reveal malpractice. What has not been appreciated, pathologists and public health officials say, are the far-reaching consequences for U.S. healthcare of minuscule autopsy rates. More



New drug stops Alzheimer's in mice
Psych Central    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at California's Salk Institute say they have developed a new drug that holds potential for halting the mental decline associated with Alzheimer's disease. In a study, the drug improved memory and prevented brain damage in mice. Although it is yet unknown whether the compound will prove safe and effective in humans, Salk researchers say their results suggest the drug is promising for treatment of people with Alzheimer's. More


New IHC
Triple Staining Kits

GBI, Labs is a leading company who supplies high quality polymer HRP and AP IHC detection kits for mouse, rabbit, goat, rat, Armenia hamster, sheep, guinea pig and chicken primary antibodies. It is the only supplier who has more than 50 products for IHC double and triple staining for human and mouse (or other animal) tissues. MORE
New Microtome Blades from Sturkey!
C.L. Sturkey proudly introduces, Select microtome blades. Select is an ideal all-purpose blade that cuts any tissue (hard or soft, large or small) with precision to 3 microns. Proudly Made in the USA and backed by our Unconditional Guarantee. Support US manufacturing jobs and call today for free samples!
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Customizable Micro-Slide & Tissue Shelving System

Lab Storage Systems offers efficient, customizable storage for up to 60 of their popular Micro-Slide and/or Tissue Storage Units. System features an optional, retractable workshelf for easy filing and retrieval. Heavy-duty, rigid 11 gauge steel construction ensures stability. Add-on units available for continuous shelving options.


Wound-treating jelly regenerates fresh, scar-free skin
Popular Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Tissue engineering and tissue healing have a common complication — it's difficult to build new blood vessels throughout the rebuilt skin, but vasculature is required to keep the skin alive. This is especially problematic for victims of severe burns. A new customized sugary gel substance can work wonders to re-grow skin and the associated blood vessels, according to researchers at Johns Hopkins University. More



Bone marrow transplant best for boosting blood cells
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Bone marrow transplants may beat stem-cell injections as a way of increasing the production of blood cells when tissue is from an unrelated donor. A potential problem of either treatment — used for diseases like sickle cell anemia — is graft-versus-host disease. This potentially fatal condition occurs when donated blood cells launch an immune attack on the host. More


HEMO-DE®

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Epitomics MSH6 Rabbit Monoclonal Antibodies
In a recent comparison study, Epitomics MSH6 antibody (EP49) had the highest quality performance in a panel of 15 vendors. See the comparisons here. MORE


Red raspberry extract may help arthritis
EmaxHealth    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study suggests red raspberries are not just another great-tasting fruit. Researchers at the University of Rhode Island report that red raspberry extract reduced inflammation, cartilage damage, and bone resorption and thus may prove helpful in modulating the development and severity of arthritis. Berries as a whole are power houses of antioxidants that also boast anti-inflammatory properties. More



Blood test predicts effectiveness of antidepressants
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Loyola University Medical Center researchers report what could become the first reliable method to predict whether an antidepressant will work on a depressed patient. A Loyola study found that among depressed patients who had higher than normal blood levels of protein vascular endothelial growth factor, more than 85 percent experienced partial or complete relief from depression after taking escitalopram. To compare, fewer than 10 percent of depressed patients who had low levels of VEGF responded to the drug. More


DIGITAL HOLOGRAPHY FOR CELL STUDY

NanoAndMore USA provides DHMs from Lyncée tec and Resolution Optics. They sense the change in the liquid content of cells and image in 3D.
MORE
Milestone
Milestone was founded in 1988 as a company specializing in advanced microwave instrumentation for analytical and organic chemistry labs. MORE


Aspirin may reduce risk of repeat blood clots
WebMd    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A low dose of daily aspirin, taken after completing six to 12 months of anti-clotting drug treatment, may help prevent the recurrence of deadly blood clots, a new study shows. One doctor went so far as to call the preliminary study a potential "game changer." The clots, known as venous thromboembolism, often occur in the legs. They can travel to the lungs and sometimes be fatal. More

Fake 'intestine' may help kids feel better
Futurity    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Children with short bowel syndrome are unable to absorb food properly and need to have nutrients administered directly into their veins. The majority of children with the condition require an intestine transplant — which is limited by a lack of suitable donors and complications from immunosuppressive therapy. Professors from Cornell University and the University of Pittsburgh are collaborating to turn a research tool into an artificial intestine to be transplanted into children with SBS. More


Tissue imaging in any mode
From fast and flexible Pannoramic™ whole slide imaging systems to powerful and affordable multi-label microscopy imaging and analysis systems, we help you get the best brightfield and fluorescence images and data possible. TRIO™ makes multi-label imaging easy, Nuance™ merges power and flexibility, and inForm™ software automates quantitative image analysis.
Tailored solutions for the lab
At Cardinal Health, we’re committed to providing you with cost-effective solutions for the management of your day-to-day business operations. From state-of-the-art laboratory products and customized distribution solutions to services that eliminate error and waste. For more information, contact your Cardinal Health sales representative or call 800.964.5227 or visit cardinalhealth.com.
Paperless Histology Tracking from PDS
Efficient paperless histology tracking for preclinical studies is here! See how the PathData System can bring smart, flexible solutions to your lab. Click PDS eTissueBase.
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Under the Microscope
Colby Horton, Vice President of Publishing, 469.420.2601
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Christine Kraly, Content Editor, 469.420.2685   
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