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Children's hearing loss from cisplatin chemotherapy associated with gene variants

from Medscape Medical News

Scientists at the University of British Columbia, Vancouver, Canada, have identified genetic variants associated with ototoxicity that occur in more than half of children treated with cisplatin. The report, published in Nature Genetics, raises the possibilities that individuals at higher genetic risk for ototoxicity could receive lower cisplatin doses, alternative drug treatments, or be chosen for otoprotectant studies. more

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