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PARP inhibitor for triple-negative breast cancer

from Medscape Medical News

The investigational agent iniparib (Sanofi-Aventis) improved a number of clinical measures, including overall survival, in women with metastatic triple-negative breast cancer, according to final phase 2 study results. The results for iniparib, which inhibits PARP, or poly(adenosine-disposphate-ribose) polymerase, were presented earlier at the 2010 European Society for Medical Oncology Congress and have been published online in the New England Journal of Medicine. more

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