Researchers mimic body's own healing potential to create personalized therapies for inflammation
Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School in Boston have found a way of mimicking the body's natural mechanism of fighting inflammation. During inflammation, cells release very small particles termed "microparticles" that retain features of their parent cell. The scientists discovered that certain microparticles were beneficial to health, and that these microparticles contained anti-inflammatory lipids, which help terminate inflammation and return the body to its normal balance. The discovery, featured online in the current edition of the Journal of Immunology, paves the way for new personalized treatments to target uncontrolled inflammation that need not rely on synthetic biomaterials, therefore reducing potential toxicity.
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