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Enzymes possible targets for new anti-malaria drugs

from Medical Xpress

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source. They have validated that two of these parasite enzymes called peptidases are potential anti-malarial drug targets. The research appeared in an early online edition of the Proceedings of the National Academy Sciences. more


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