Preoperative chlorhexidine wash superior to povidone-iodine
from Medscape Medical News
Using chlorhexidine as a preoperative surgical wash cut the risk for a surgical site infection in half, compared with washing with 10 percent povidone-iodine, investigators from the Singapore General Hospital reported at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chlorhexidine and povidone-iodine, both used preoperatively to reduce SSIs, have similar spectra of bactericidal activity, but differences in their effectiveness in eradicating microbes have been reported. Investigators, led by pharmacist Yixin Liew, performed a meta-analysis to evaluate the effectiveness of a chlorhexidine bath in reducing the rate of SSIs.
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