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Study: Late-life depression may be associated with MCI and dementia

from Archives of Neurology

Archives of Neurology News Release (Dec. 31): Older people with depression may be more likely to experience mild mental impairment or dementia than their peers, Dutch researchers report. In a study of nearly 2,200 Medicare recipients aged 65 and older, researchers led by Dr. Edo Richard of the University of Amsterdam in the Netherlands examined the association between late-life depression and dementia and thinking/memory difficulties known as mild cognitive impairment (MCI). The study, published online Dec. 31 in the journal Archives of Neurology, found that people with depression were 40 percent more likely to have mild mental impairment and more than twice as likely to have full-blown dementia. Although depression also was linked to greater risk for incident dementia, it was not associated with incident problems with thinking and memory. The study authors said those with both mild cognitive impairment and depression were at increased risk for developing dementia, particularly vascular dementia. They noted, however, that these patients were not at greater risk for Alzheimer's disease, the most common form of dementia. more


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