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Lab-on-a-chip detects periodontitis pathogens


A new mobile diagnostic platform developed by a team of German researchers can be used in a dental office to analyze DNA collected from teeth and identify the 11 most relevant periodontitis pathogens in less than 30 minutes. Scientists at the Fraunhofer Institute for Cell Therapy and Immunology collaborated with BECIT and ERT-Optik to develop ParoChip, a lab-on-a-chip module designed to allow dentists and medical labs to prepare samples quickly and then analyze the bacteria. All steps in the process — the duplication of DNA sequences and their detection — take place directly on the platform, which consists of a disk-shaped microfluidic card that measures about 6 centimeter in diameter. (May require free registration to view article.) more

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